PMID- 32971774
OWN - NLM
STAT- MEDLINE
DCOM- 20210325
LR  - 20210325
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 12
IP  - 9
DP  - 2020 Sep 22
TI  - Pre-Sleep Low Glycemic Index Modified Starch Does Not Improve Next-Morning Fuel 
      Selection or Running Performance in Male and Female Endurance Athletes.
LID - 10.3390/nu12092888 [doi]
LID - 2888
AB  - To determine the effects of pre-sleep supplementation with a novel low glycemic 
      index (LGI) carbohydrate (CHO) on next-morning substrate utilization, 
      gastrointestinal distress (GID), and endurance running performance (5-km 
      time-trial, TT). Using a double-blind, randomized, placebo (PLA) controlled, 
      crossover design, trained participants (n = 14; 28 +/- 9 years, 8/6 male/female, 55 
      +/- 7 mL/kg/min) consumed a LGI, high glycemic index (HGI), or 0 kcal PLA 
      supplement >/= 2 h after their last meal and <30 min prior to sleep. Upon arrival, 
      resting energy expenditure (REE), substrate utilization, blood glucose, satiety, 
      and GID were assessed. An incremental exercise test (IET) was performed at 55, 
      65, and 75% peak volume of oxygen consumption (VO(2peak)) with GID, rating of 
      perceived exertion (RPE) and substrate utilization recorded each stage. Finally, 
      participants completed the 5-km TT. There were no differences in any baseline 
      measure. During IET, CHO utilization tended to be greater with LGI (PLA, 56 +/- 11; 
      HGI, 60 +/- 14; LGI, 63 +/- 14%, p = 0.16, eta(2) = 0.14). GID was unaffected by 
      supplementation at any point (p > 0.05). Performance was also unaffected by 
      supplement (PLA, 21.6 +/- 9.5; HGI, 23.0 +/- 7.8; LGI, 24.1 +/- 4.5 min, p = 0.94, eta(2) 
      = 0.01). Pre-sleep CHO supplementation did not affect next-morning resting 
      metabolism, BG, GID, or 5-km TT performance. The trend towards higher CHO 
      utilization during IET after pre-sleep LGI, suggests that such supplementation 
      increases morning CHO availability.
FAU - Dudar, Monique D
AU  - Dudar MD
AD  - Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, NY 
      12866, USA.
FAU - Bode, Emilie D
AU  - Bode ED
AD  - Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, NY 
      12866, USA.
FAU - Fishkin, Karly R
AU  - Fishkin KR
AD  - Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, NY 
      12866, USA.
FAU - Brown, Rochelle A
AU  - Brown RA
AD  - Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, NY 
      12866, USA.
FAU - Carre, Madeleine M
AU  - Carre MM
AD  - Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, NY 
      12866, USA.
FAU - Mills, Noa R
AU  - Mills NR
AD  - Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, NY 
      12866, USA.
FAU - Ormsbee, Michael J
AU  - Ormsbee MJ
AUID- ORCID: 0000-0002-1939-7656
AD  - Department of Nutrition, Food, and Exercise Sciences, Institute of Sport Sciences 
      and Medicine, Florida State University, Tallahassee, FL 32306, USA.
AD  - Department of Biokinetics, Exercise and Leisure Sciences, School of Health 
      Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.
FAU - Ives, Stephen J
AU  - Ives SJ
AUID- ORCID: 0000-0002-7722-8818
AD  - Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, NY 
      12866, USA.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20200922
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Placebos)
RN  - 9005-25-8 (Starch)
SB  - IM
MH  - Adult
MH  - *Athletes
MH  - Athletic Performance/*physiology
MH  - Blood Glucose/analysis
MH  - Cross-Over Studies
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Double-Blind Method
MH  - Energy Metabolism/drug effects
MH  - Female
MH  - *Glycemic Index
MH  - Humans
MH  - Male
MH  - Oxygen Consumption
MH  - Physical Endurance/drug effects
MH  - Placebos
MH  - Running/*physiology
MH  - Satiation
MH  - Sleep
MH  - Starch/*administration & dosage
PMC - PMC7551949
OTO - NOTNLM
OT  - carbohydrates
OT  - exercise
OT  - fat oxidation
OT  - fatigue
OT  - gastrointestinal distress
OT  - satiety
OT  - substrate utilization
OT  - time trial
COIS- The authors declare no conflict of interest.
EDAT- 2020/09/26 06:00
MHDA- 2021/03/26 06:00
PMCR- 2020/09/01
CRDT- 2020/09/25 01:00
PHST- 2020/08/30 00:00 [received]
PHST- 2020/09/16 00:00 [revised]
PHST- 2020/09/17 00:00 [accepted]
PHST- 2020/09/25 01:00 [entrez]
PHST- 2020/09/26 06:00 [pubmed]
PHST- 2021/03/26 06:00 [medline]
PHST- 2020/09/01 00:00 [pmc-release]
AID - nu12092888 [pii]
AID - nutrients-12-02888 [pii]
AID - 10.3390/nu12092888 [doi]
PST - epublish
SO  - Nutrients. 2020 Sep 22;12(9):2888. doi: 10.3390/nu12092888.