PMID- 32976167
OWN - NLM
STAT- MEDLINE
DCOM- 20210120
LR  - 20210206
IS  - 1524-4725 (Electronic)
IS  - 1076-0512 (Linking)
VI  - 46 Suppl 1
DP  - 2020 Oct
TI  - Adverse Events Associated With Cryolipolysis: A Systematic Review of the 
      Literature.
PG  - S8-S13
LID - 10.1097/DSS.0000000000002524 [doi]
AB  - BACKGROUND: Cryolipolysis is a popular procedure for people seeking noninvasive 
      body contouring. As with any novel therapy, it is critical for providers to 
      familiarize themselves with related adverse events (AEs), to provide appropriate 
      information to patients before treatment. OBJECTIVE: To describe reported 
      complications and AEs associated with cryolipolysis. MATERIALS AND METHODS: A 
      systematic review was completed using the PubMed database and following search 
      terms: "cryolipolysis" or "lipocryolysis" or "CoolSculpting." Only randomized 
      clinical trials, prospective cohort studies, retrospective studies, case series, 
      and case reports describing AEs related to cryolipolysis as well as studies 
      written in English were included for review. RESULTS: Fifty-three articles were 
      included in this review. The most common AEs associated with cryolipolysis were 
      treatment site erythema, numbness/paresthesia, bruising, and edema. More serious 
      complications of cryolipolysis include severe/persistent pain, dysesthesia, skin 
      hyperpigmentation, motor neuropathy, and paradoxical adipose hyperplasia. 
      CONCLUSION: Cryolipolysis is a safe option for patients seeking noninvasive body 
      contouring. Most reported AEs are minimal and resolve quickly. It is important 
      that physicians are aware of serious, irreversible AEs and are prepared to 
      counsel patients appropriately before treatment.
FAU - Hedayati, Bobak
AU  - Hedayati B
AD  - School of Medicine, University of California, Irvine, California.
FAU - Juhasz, Margit
AU  - Juhasz M
AD  - Department of Dermatology, University of California, Irvine, California.
FAU - Chu, Sherman
AU  - Chu S
AD  - Western University of Health Sciences, College of Osteopathic Medicine of the 
      Pacific, Northwest, Lebanon, Oregon.
FAU - Mesinkovska, Natasha Atanaskova
AU  - Mesinkovska NA
AD  - Department of Dermatology, University of California, Irvine, California.
LA  - eng
PT  - Journal Article
PT  - Systematic Review
PL  - United States
TA  - Dermatol Surg
JT  - Dermatologic surgery : official publication for American Society for Dermatologic 
      Surgery [et al.]
JID - 9504371
SB  - IM
MH  - Cryosurgery/*adverse effects/methods
MH  - Humans
MH  - Lipectomy/*adverse effects/methods
MH  - Patient Satisfaction
MH  - Randomized Controlled Trials as Topic
MH  - Treatment Outcome
EDAT- 2020/09/26 06:00
MHDA- 2021/01/21 06:00
CRDT- 2020/09/25 17:10
PHST- 2020/09/25 17:10 [entrez]
PHST- 2020/09/26 06:00 [pubmed]
PHST- 2021/01/21 06:00 [medline]
AID - 00042728-202010001-00003 [pii]
AID - 10.1097/DSS.0000000000002524 [doi]
PST - ppublish
SO  - Dermatol Surg. 2020 Oct;46 Suppl 1:S8-S13. doi: 10.1097/DSS.0000000000002524.