PMID- 32981643 OWN - NLM STAT- MEDLINE DCOM- 20211011 LR - 20211204 IS - 1558-3163 (Electronic) IS - 0889-857X (Linking) VI - 46 IP - 4 DP - 2020 Nov TI - Disparities in Childhood-Onset Lupus. PG - 661-672 LID - S0889-857X(20)30079-X [pii] LID - 10.1016/j.rdc.2020.07.007 [doi] AB - Disparities in prevalence, disease severity, physical and mental morbidity, and mortality exist in childhood-onset systemic lupus (cSLE) that lead to worse outcomes in children with systemic lupus erythematosus from socially disadvantaged backgrounds. Important gaps exist in knowledge regarding many individual race/ethnicities across the globe, the interaction between race/ethnicity and poverty, and drivers for identified disparities. Large cSLE registries will facilitate investigating disparities in groups of patients that have yet to be identified. Social-ecological models can inform approaches to investigate, monitor, and address disparities in cSLE. CI - Copyright (c) 2020 Elsevier Inc. All rights reserved. FAU - Rubinstein, Tamar B AU - Rubinstein TB AD - Department of Pediatrics, Division of Pediatric Rheumatology, Children's Hospital at Montefiore/Albert Einstein College of Medicine, 3415 Bainbridge Avenue, Bronx, NY 10467, USA. Electronic address: trubinst@montefiore.org. FAU - Knight, Andrea M AU - Knight AM AD - Division of Rheumatology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20200909 PL - United States TA - Rheum Dis Clin North Am JT - Rheumatic diseases clinics of North America JID - 8708093 SB - IM MH - Age of Onset MH - Child MH - *Health Status Disparities MH - Humans MH - *Lupus Erythematosus, Systemic/epidemiology/ethnology MH - Poverty MH - Racial Groups MH - *Vulnerable Populations/ethnology OTO - NOTNLM OT - Access OT - Disparities OT - Ethnicity OT - Geographic OT - Lupus OT - Pediatric OT - Race OT - Socioeconomic COIS- Disclosure Funder: The Hospital for Sick Children, Ontario, Canada. EDAT- 2020/09/29 06:00 MHDA- 2021/10/12 06:00 CRDT- 2020/09/28 05:32 PHST- 2020/09/28 05:32 [entrez] PHST- 2020/09/29 06:00 [pubmed] PHST- 2021/10/12 06:00 [medline] AID - S0889-857X(20)30079-X [pii] AID - 10.1016/j.rdc.2020.07.007 [doi] PST - ppublish SO - Rheum Dis Clin North Am. 2020 Nov;46(4):661-672. doi: 10.1016/j.rdc.2020.07.007. Epub 2020 Sep 9.