PMID- 32989960 OWN - NLM STAT- MEDLINE DCOM- 20210910 LR - 20211207 IS - 2724-5772 (Electronic) IS - 2724-5683 (Linking) VI - 69 IP - 1 DP - 2021 Feb TI - Factors associated with recurrent postinfarction ventricular tachycardia following ablation. PG - 50-60 LID - 10.23736/S2724-5683.20.05128-2 [doi] AB - INTRODUCTION: Ablation of ventricular tachycardia is the main therapy for patients with drug-refractory ventricular tachycardia (VT). Although evidence suggests that VT ablation could lower the incidence of recurrent VT, many cases still develop VT in follow-up. In this study, we performed a systematic review and meta-analysis to examine risk factors for recurrent VT in patients with postinfarction VT who underwent VT ablation. EVIDENCE ACQUISITION: We comprehensively searched the databases of MEDLINE and EMBASE from inception to March 2020. Included studies were cohort studies, experimental trials, or randomized controlled trials that evaluate the risk of recurrent VT in postinfarction VT patients who underwent VT ablation. Data from each study were combined using random-effects. EVIDENCE SYNTHESIS: Thirteen studies involving 1803 postinfarction patients who underwent VT ablation were included. Inducibility after the procedure (pooled HR=1.71, P<0.001), lower baseline left ventricular ejection fraction (LVEF) (pooled HR=0.98, P<0.001) and higher baseline New York Heart Association (NYHA) classification (pooled HR=1.34, P=0.003) were significantly associated with VT recurrence during the follow-up. There was no significant association between age, gender or diabetes mellitus and VT recurrence. CONCLUSIONS: Our meta-analysis demonstrated that inducibility after the procedure, lower baseline LVEF and higher baseline NYHA classification were associated with an increased risk of VT recurrence in postinfarction VT patients who underwent VT ablation. FAU - Kewcharoen, Jakrin AU - Kewcharoen J AD - University of Hawaii Internal Medicine Residency Program, Honolulu, HI, USA - jakrin@hawaii.edu. FAU - Prasitlumkum, Narut AU - Prasitlumkum N AD - University of Hawaii Internal Medicine Residency Program, Honolulu, HI, USA. FAU - Titichoatrattana, Sittinop AU - Titichoatrattana S AD - Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. FAU - Wittayalikit, Chutikarn AU - Wittayalikit C AD - Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. FAU - Trongtorsak, Angkawipa AU - Trongtorsak A AD - Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. FAU - Kanitsoraphan, Chanavuth AU - Kanitsoraphan C AD - University of Hawaii Internal Medicine Residency Program, Honolulu, HI, USA. FAU - Putthapiban, Prapaipan AU - Putthapiban P AD - Department of Medicine, Einstein Medical Center, Philadelphia, PA, USA. FAU - Poonsombudlert, Kittika AU - Poonsombudlert K AD - University of Hawaii Internal Medicine Residency Program, Honolulu, HI, USA. FAU - Rattanawong, Pattara AU - Rattanawong P AD - Department of Cardiovascular Diseases, Mayo Clinic, Phoenix, AZ, USA. AD - Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. FAU - Chung, Eugene H AU - Chung EH AD - Department of Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review DEP - 20200929 PL - Italy TA - Minerva Cardiol Angiol JT - Minerva cardiology and angiology JID - 101776555 SB - IM MH - *Catheter Ablation MH - Humans MH - Recurrence MH - Stroke Volume MH - *Tachycardia, Ventricular/surgery MH - Ventricular Function, Left EDAT- 2020/09/30 06:00 MHDA- 2021/09/11 06:00 CRDT- 2020/09/29 05:49 PHST- 2020/09/30 06:00 [pubmed] PHST- 2021/09/11 06:00 [medline] PHST- 2020/09/29 05:49 [entrez] AID - S0026-4725.20.05128-2 [pii] AID - 10.23736/S2724-5683.20.05128-2 [doi] PST - ppublish SO - Minerva Cardiol Angiol. 2021 Feb;69(1):50-60. doi: 10.23736/S2724-5683.20.05128-2. Epub 2020 Sep 29.