PMID- 32999239
OWN - NLM
STAT- MEDLINE
DCOM- 20210414
LR  - 20240331
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Print)
IS  - 0918-2918 (Linking)
VI  - 60
IP  - 5
DP  - 2021 Mar 1
TI  - Anti-glomerular Basement Membrane Glomerulonephritis During the First Trimester 
      of Pregnancy.
PG  - 765-770
LID - 10.2169/internalmedicine.5722-20 [doi]
AB  - A 28-year-old woman was admitted during the eighth week of her pregnancy because 
      her clinical course was consistent with rapid progressive glomerulonephritis 
      (RPGN). Anti-glomerular basement membrane antibody (anti-GBM Ab) and 
      myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) were positive, 
      and the anti-GBM Ab titer being extremely high. She was treated with 
      hemodialysis, plasma exchange and prednisolone. She survived the illness; 
      however, neither the fetus nor her kidney function could be rescued. She had 
      human leukocyte antigen (HLA)-DRB1*1502:01, which differs from the DRB1*1501 
      associated with anti-GBM GN. When patients have particular symptoms, we should 
      check the urine and serum creatinine to exclude RPGN, even in cases of pregnancy.
FAU - Kai, Hirayasu
AU  - Kai H
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Usui, Joichi
AU  - Usui J
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Tawara, Takashi
AU  - Tawara T
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Takahashi-Kobayashi, Mayumi
AU  - Takahashi-Kobayashi M
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Ishii, Ryota
AU  - Ishii R
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Tsunoda, Ryoya
AU  - Tsunoda R
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Fujita, Akiko
AU  - Fujita A
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Nagai, Kei
AU  - Nagai K
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Kaneko, Shuzo
AU  - Kaneko S
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Morito, Naoki
AU  - Morito N
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Saito, Chie
AU  - Saito C
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
FAU - Hamada, Hiromi
AU  - Hamada H
AD  - Division of Clinical Medicine, Department of Obstetrics & Gynecology, Faculty of 
      Medicine, University of Tsukuba, Japan.
FAU - Yamagata, Kunihiro
AU  - Yamagata K
AD  - Division of Clinical Medicine, Department of Nephrology, Faculty of Medicine, 
      University of Tsukuba, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20200930
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (Antibodies, Antineutrophil Cytoplasmic)
RN  - 0 (Autoantibodies)
RN  - EC 1.11.1.7 (Peroxidase)
SB  - IM
MH  - Adult
MH  - Antibodies, Antineutrophil Cytoplasmic
MH  - Autoantibodies
MH  - Female
MH  - *Glomerulonephritis/diagnosis
MH  - Humans
MH  - Kidney Glomerulus
MH  - *Peroxidase
MH  - Pregnancy
MH  - Pregnancy Trimester, First
PMC - PMC7990629
OTO - NOTNLM
OT  - 1st trimester of pregnancy
OT  - HLA-DRB1*1502:01
OT  - anti-glomerular basement membrane glomerulonephritis (anti-GBM GN)
OT  - plasma exchange (PE)
OT  - rapid progressive glomerulonephritis (RPGN)
COIS- The authors state that they have no Conflict of Interest (COI).
EDAT- 2020/10/02 06:00
MHDA- 2021/04/15 06:00
PMCR- 2021/03/01
CRDT- 2020/10/01 05:31
PHST- 2020/10/02 06:00 [pubmed]
PHST- 2021/04/15 06:00 [medline]
PHST- 2020/10/01 05:31 [entrez]
PHST- 2021/03/01 00:00 [pmc-release]
AID - 10.2169/internalmedicine.5722-20 [doi]
PST - ppublish
SO  - Intern Med. 2021 Mar 1;60(5):765-770. doi: 10.2169/internalmedicine.5722-20. Epub 
      2020 Sep 30.