PMID- 32999682
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220417
IS  - 1710-1484 (Print)
IS  - 1710-1492 (Electronic)
IS  - 1710-1484 (Linking)
VI  - 16
DP  - 2020
TI  - The association of asthma and its subgroups with osteoporosis: a cross-sectional 
      study using KoGES HEXA data.
PG  - 84
LID - 10.1186/s13223-020-00482-6 [doi]
LID - 84
AB  - BACKGROUND: A few studies have reported the association between asthma and 
      osteoporosis. We aimed to analyze the association of asthma and its subgroups 
      with osteoporosis in the Korean adult population. METHODS: We used the health 
      examinee (HEXA) data from the Korean Genome and Epidemiology Study (KoGES) 
      obtained between 2004 and 2016. We included 162,579 participants (n = 3,160 with 
      asthma; n = 159,419 controls) who reported their previous histories of asthma and 
      osteoporosis. The participants were categorized into 3 groups based on asthma 
      management: participants who did not need further treatment due to controlled 
      symptoms (well controlled); participants with ongoing treatment (being treated); 
      participants who were not treated even though they had symptoms (not being 
      treated). Multiple logistic regression analyses were used to calculate the 
      adjusted odds ratios (aORs) with 95% confidence intervals (CIs) for osteoporosis. 
      Subgroup analyses for age and sex were conducted. RESULTS: The prevalence of 
      osteoporosis was higher in patients with asthma (13.6%) than in controls (6.8%). 
      In the full-adjusted model, the aORs for osteoporosis were 1.74 (95% CI 
      1.55-1.94, P < 0.001) in patients with asthma compared to controls. There were 
      consistent findings across the age and sex subgroups. The aORs for osteoporosis 
      were 1.43 (95% CI 1.10-1.86, P = 0.008) in the well-controlled asthma group; 1.55 
      (95% CI 1.28-1.89, P < 0.001) in the being treated asthma group; and 1.96 (95% CI 
      1.66-2.31, P < 0.001) in the not being treated asthma group compared to the 
      control group. CONCLUSION: Asthma was associated with osteoporosis in the Korean 
      adult population. Patients with asthma not being treated showed the highest ORs 
      for osteoporosis.
CI  - (c) The Author(s) 2020.
FAU - Wee, Jee Hye
AU  - Wee JH
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Sacred 
      Heart Hospital, 22, Gwanpyeong-ro 170 beon-gil, Dongan-gu, Anyang, 14068 Republic 
      of Korea. GRID: grid.488421.3. ISNI: 0000000404154154
FAU - Min, Chanyang
AU  - Min C
AD  - Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang, 
      Korea. GRID: grid.256753.0. ISNI: 0000 0004 0470 5964
AD  - Graduate School of Public Health, Seoul National University, Seoul, South Korea. 
      GRID: grid.31501.36. ISNI: 0000 0004 0470 5905
FAU - Park, Min Woo
AU  - Park MW
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Kangdong Sacred Heart 
      Hospital, Seoul, South Korea. GRID: grid.488451.4. ISNI: 0000 0004 0570 3602
FAU - Byun, Soo Hwan
AU  - Byun SH
AD  - Department of Oral and Maxillofacial Surgery, Dentistry, Hallym University 
      College of Medicine, Anyang, South Korea. GRID: grid.256753.0. ISNI: 0000 0004 
      0470 5964
FAU - Lee, Hyo-Jeong
AU  - Lee HJ
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Sacred 
      Heart Hospital, 22, Gwanpyeong-ro 170 beon-gil, Dongan-gu, Anyang, 14068 Republic 
      of Korea. GRID: grid.488421.3. ISNI: 0000000404154154
FAU - Park, Bumjung
AU  - Park B
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Sacred 
      Heart Hospital, 22, Gwanpyeong-ro 170 beon-gil, Dongan-gu, Anyang, 14068 Republic 
      of Korea. GRID: grid.488421.3. ISNI: 0000000404154154
FAU - Choi, Hyo Geun
AU  - Choi HG
AUID- ORCID: 0000-0003-1655-9549
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Sacred 
      Heart Hospital, 22, Gwanpyeong-ro 170 beon-gil, Dongan-gu, Anyang, 14068 Republic 
      of Korea. GRID: grid.488421.3. ISNI: 0000000404154154
AD  - Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang, 
      Korea. GRID: grid.256753.0. ISNI: 0000 0004 0470 5964
LA  - eng
PT  - Journal Article
DEP - 20200925
PL  - England
TA  - Allergy Asthma Clin Immunol
JT  - Allergy, asthma, and clinical immunology : official journal of the Canadian 
      Society of Allergy and Clinical Immunology
JID - 101244313
PMC - PMC7519551
OTO - NOTNLM
OT  - Asthma
OT  - Chronic disease
OT  - Epidemiology
OT  - Osteoporosis
COIS- Competing interestsThe authors declare no conflict of interest.
EDAT- 2020/10/02 06:00
MHDA- 2020/10/02 06:01
PMCR- 2020/09/25
CRDT- 2020/10/01 05:37
PHST- 2020/06/15 00:00 [received]
PHST- 2020/09/15 00:00 [accepted]
PHST- 2020/10/01 05:37 [entrez]
PHST- 2020/10/02 06:00 [pubmed]
PHST- 2020/10/02 06:01 [medline]
PHST- 2020/09/25 00:00 [pmc-release]
AID - 482 [pii]
AID - 10.1186/s13223-020-00482-6 [doi]
PST - epublish
SO  - Allergy Asthma Clin Immunol. 2020 Sep 25;16:84. doi: 10.1186/s13223-020-00482-6. 
      eCollection 2020.