PMID- 33006131
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201112
IS  - 1869-6953 (Print)
IS  - 1869-6961 (Electronic)
IS  - 1869-6961 (Linking)
VI  - 11
IP  - 12
DP  - 2020 Dec
TI  - Does Roux-en-Y Construction Really Bring Benefit of Type 2 Diabetes Mellitus 
      Remission After Gastrectomy in Patients with Gastric Cancer? A Systematic Review 
      and Meta-Analysis.
PG  - 2863-2872
LID - 10.1007/s13300-020-00934-7 [doi]
AB  - INTRODUCTION: To evaluate whether the extent of gastrectomy or the reconstruction 
      method brings benefit of type 2 diabetes mellitus (T2DM) remission after 
      gastrectomy in patients with gastric cancer. METHODS: PUBMED, EMBASE, the 
      Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library 
      were searched to find eligible studies published from inception to July 31, 2020. 
      RESULTS: A total of nine studies (1424 patients) were included. At the first year 
      and the end of follow-up time after gastrectomy, the total gastrectomy group had 
      better T2DM remission than the subtotal gastrectomy group, and the Roux-en-Y 
      reconstruction (R-Y) group had better T2DM remission compared with the non-R-Y 
      group. There was no difference between R-Y and non-R-Y in terms of subtotal 
      gastrectomy (OR 1.08, 95% CI 0.63-1.84, P = 0.78). However, total gastrectomy 
      with R-Y had better T2DM remission than subtotal gastrectomy with R-Y (OR 2.75, 
      95% CI 1.19-6.35, P = 0.02). CONCLUSION: Total gastrectomy with R-Y had better 
      T2DM remission. The extent of gastrectomy rather than the reconstruction method 
      might play an important role in T2DM remission after gastrectomy in patients with 
      gastric cancer.
FAU - Peng, Dong
AU  - Peng D
AD  - Department of Gastrointestinal Surgery, The First Affiliated Hospital of 
      Chongqing Medical University, Chongqing, China.
FAU - Cheng, Yu-Xi
AU  - Cheng YX
AD  - Department of Gastrointestinal Surgery, The First Affiliated Hospital of 
      Chongqing Medical University, Chongqing, China.
FAU - Zhang, Wei
AU  - Zhang W
AUID- ORCID: 0000-0002-5822-9970
AD  - Department of Gastrointestinal Surgery, The First Affiliated Hospital of 
      Chongqing Medical University, Chongqing, China. cyzhangwei@hotmail.com.
LA  - eng
PT  - Journal Article
DEP - 20201001
PL  - United States
TA  - Diabetes Ther
JT  - Diabetes therapy : research, treatment and education of diabetes and related 
      disorders
JID - 101539025
PMC - PMC7644734
OTO - NOTNLM
OT  - Gastrectomy
OT  - Gastric cancer
OT  - Remission
OT  - Roux-en-Y reconstruction
OT  - Type 2 diabetes mellitus
EDAT- 2020/10/03 06:00
MHDA- 2020/10/03 06:01
PMCR- 2020/10/01
CRDT- 2020/10/02 05:48
PHST- 2020/08/14 00:00 [received]
PHST- 2020/09/16 00:00 [accepted]
PHST- 2020/10/03 06:00 [pubmed]
PHST- 2020/10/03 06:01 [medline]
PHST- 2020/10/02 05:48 [entrez]
PHST- 2020/10/01 00:00 [pmc-release]
AID - 10.1007/s13300-020-00934-7 [pii]
AID - 934 [pii]
AID - 10.1007/s13300-020-00934-7 [doi]
PST - ppublish
SO  - Diabetes Ther. 2020 Dec;11(12):2863-2872. doi: 10.1007/s13300-020-00934-7. Epub 
      2020 Oct 1.