PMID- 33012917
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210507
IS  - 0165-8107 (Print)
IS  - 1744-506X (Electronic)
IS  - 0165-8107 (Linking)
VI  - 44
IP  - 5
DP  - 2020
TI  - The Relationship between Intraocular Pressure and Optic Nerve Structural and 
      Functional Damage in Patients with Optic Nerve Head Drusen.
PG  - 290-293
LID - 10.1080/01658107.2019.1691242 [doi]
AB  - The aim of this retrospective study was to evaluate if, in ocular normotensive 
      patients, at the time of diagnosis of optic nerve head drusen (ONHD), perimetric 
      mean deviation (PMD) on visual field (VF) examination and retinal nerve fibre 
      layer (RNFL) thickness on optical coherence tomography correlated with 
      intraocular pressure (IOP). There was a significant association between IOP and 
      PMD (Spearman's rho = -0.863, p < .01) and between IOP and RNFL thickness 
      (Spearman's rho = -0.630, p < .01). A higher IOP was associated with a greater 
      functional loss in the VF and a reduction in the RNFL thickness. These results 
      suggest that a clinical trial of IOP reduction should be considered in patients 
      with ONHD to decrease the progression of optic nerve damage over time.
CI  - (c) 2019 Taylor & Francis Group, LLC.
FAU - Oliveira-Ferreira, Claudia
AU  - Oliveira-Ferreira C
AUID- ORCID: 0000-0002-9446-7140
AD  - Ophthalmology Department, Centro Hospitalar Sao Joao, Oporto, Portugal.
FAU - Leuzinger-Dias, Mariana
AU  - Leuzinger-Dias M
AD  - Ophthalmology Department, Centro Hospitalar Sao Joao, Oporto, Portugal.
FAU - Tavares-Ferreira, Joao
AU  - Tavares-Ferreira J
AUID- ORCID: 0000-0002-5283-2939
AD  - Ophthalmology Department, Centro Hospitalar Sao Joao, Oporto, Portugal.
FAU - Faria, Olinda
AU  - Faria O
AD  - Ophthalmology Department, Centro Hospitalar Sao Joao, Oporto, Portugal.
AD  - Surgery and Physiology Department, Faculty of Medicine, Porto University, Oporto, 
      Portugal.
FAU - Falcao-Reis, F
AU  - Falcao-Reis F
AD  - Ophthalmology Department, Centro Hospitalar Sao Joao, Oporto, Portugal.
AD  - Surgery and Physiology Department, Faculty of Medicine, Porto University, Oporto, 
      Portugal.
LA  - eng
PT  - Journal Article
DEP - 20191212
PL  - England
TA  - Neuroophthalmology
JT  - Neuro-ophthalmology (Aeolus Press)
JID - 8408966
PMC - PMC7518321
OTO - NOTNLM
OT  - Optic nerve head drusen
OT  - intraocular pressure
OT  - retinal nerve fibre layer
OT  - visual field
EDAT- 2020/10/06 06:00
MHDA- 2020/10/06 06:01
PMCR- 2020/12/12
CRDT- 2020/10/05 06:12
PHST- 2020/10/05 06:12 [entrez]
PHST- 2020/10/06 06:00 [pubmed]
PHST- 2020/10/06 06:01 [medline]
PHST- 2020/12/12 00:00 [pmc-release]
AID - 1691242 [pii]
AID - 10.1080/01658107.2019.1691242 [doi]
PST - epublish
SO  - Neuroophthalmology. 2019 Dec 12;44(5):290-293. doi: 
      10.1080/01658107.2019.1691242. eCollection 2020.