PMID- 33015331
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201006
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 8
IP  - 10
DP  - 2020 Oct
TI  - Endoscopic submucosal dissection and tunneling procedures using a novel 
      all-in-one bipolar device.
PG  - E1302-E1307
LID - 10.1055/a-1220-6562 [doi]
AB  - Background and study aims  Recent innovations in devices and techniques have 
      revolutionized the field of endoscopic resection procedures. In this study, we 
      evaluated the safety and feasibility of endoscopic submucosal dissection and 
      tunneling procedures with a novel, multipurpose bipolar device. Patients and 
      methods  Data from consecutive patients who underwent per-oral endoscopic myotomy 
      (POEM), submucosal tunneling endoscopic resection (STER), and endoscopic 
      submucosal dissection (ESD) using a novel bipolar device (December 2019 to 
      February 2020) were analyzed retrospectively. Procedure duration, technical 
      success, and adverse events (AEs) were recorded. Results  A total of 10 
      procedures were performed using the novel bipolar device during the study period. 
      The procedures included POEM (n = 7), STER for esophageal sub-epithelial tumor 
      (n = 1), ESD for rectal polyp (n = 1), and gastric neuroendocrine tumor (n = 1). 
      POEM was successfully completed in all patients. In patients who underwent STER 
      and ESD, en-bloc resection was achieved in all. Mean procedure time for 
      submucosal tunneling procedures (POEM and STER) was 59.12 +/- 31.12 minutes. The 
      procedures were completed without the requirement for exchange of accessories in 
      eight cases (80 %). There were no major AEs. Mild and moderate AEs occurred 
      during POEM and included capno-peritoneum (n = 1), retroperitoneal CO (2) 
      (n = 1), and empyema (n = 1). Conclusion  ESD and tunneling procedures can be 
      safely performed without the need for exchange of accessories using a novel 
      bipolar device. Randomized comparison with conventional knives isrequired to 
      confirm the utility of this device.
CI  - The Author(s). This is an open access article published by Thieme under the terms 
      of the Creative Commons Attribution-NonDerivative-NonCommercial License, 
      permitting copying and reproduction so long as the original work is given 
      appropriate credit. Contents may not be used for commecial purposes, or adapted, 
      remixed, transformed or built upon. 
      (https://creativecommons.org/licenses/by-nc-nd/4.0/).
FAU - Nabi, Zaheer
AU  - Nabi Z
AD  - Asian Institute of Gastroenterology - Medical Gastroenterology, Hyderabad, India.
FAU - Chavan, Radhika
AU  - Chavan R
AD  - Asian Institute of Gastroenterology - Gastroenterology, Hyderabad, India.
FAU - Ramchandani, Mohan
AU  - Ramchandani M
AD  - Asian Institute of Gastroenterology - Gastroenterology, Hyderabad, India.
FAU - Tsiamoulos, Zacharias
AU  - Tsiamoulos Z
AD  - St. Mark's Hospital - Gastroenterology, Harrow, UK.
FAU - Basha, Jahanqeer
AU  - Basha J
AD  - PGIMER - Gastroenterology, Chandigarh, India.
FAU - Goud, Rajesh
AU  - Goud R
AD  - Asian Institute of Gastroenterology - Gastroenterology, Hyderabad, India.
FAU - Darisetty, Santosh
AU  - Darisetty S
AD  - Asian Institute of Gastroenterology - Gastroenterology, Hyderabad, India.
AD  - Asian Institute of Gastroenterology - Anesthesia, Hyderabad, India.
FAU - Reddy, Nageshwar
AU  - Reddy N
AD  - Asian Institute of Gastroenterology - Gastroenterology, Hyderabad, India.
LA  - eng
PT  - Journal Article
DEP - 20200922
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC7511265
COIS- Competing interests Dr. Tsiamoulos is a consultant agreement for Creo Medical and 
      has received educational grants from Norgine and loan equipment from Olympus and 
      Pentax.
EDAT- 2020/10/06 06:00
MHDA- 2020/10/06 06:01
PMCR- 2020/10/01
CRDT- 2020/10/05 06:22
PHST- 2020/04/09 00:00 [received]
PHST- 2020/05/22 00:00 [accepted]
PHST- 2020/10/05 06:22 [entrez]
PHST- 2020/10/06 06:00 [pubmed]
PHST- 2020/10/06 06:01 [medline]
PHST- 2020/10/01 00:00 [pmc-release]
AID - 10.1055/a-1220-6562 [doi]
PST - ppublish
SO  - Endosc Int Open. 2020 Oct;8(10):E1302-E1307. doi: 10.1055/a-1220-6562. Epub 2020 
      Sep 22.