PMID- 33015337
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201006
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 8
IP  - 10
DP  - 2020 Oct
TI  - Suture pattern does not influence outcomes of endoscopic sleeve gastroplasty in 
      obese patients.
PG  - E1349-E1358
LID - 10.1055/a-1221-9835 [doi]
AB  - Background and study aims  ESG is an effective and safe medium-term procedure for 
      obesity treatment. A variety of suture patterns have been reported. We aimed to 
      compare whether there are differences in efficacy depending on suture pattern 
      used. Patients and methods  Retrospective and comparative review of 5 years of 
      prospectively collected data, including consecutive obese patients undergoing ESG 
      at two collaborative centers. Primary outcomes included weight loss (mainly % 
      total body weight loss [TBWL] and % exces weight loss [EWL]) at 12 months and 
      safety profile. We compared them according to three suture patterns (transverse 
      bilinear [TBp], longitudinal [Lp] and transverse monolinear [TMp]), and number of 
      sutures (4 - 7) and stitches (< 25, 25 to 30 and > 30) applied. Evolution of 
      major obesity-associated morbidities (hypertension, dyslipidemia, Type 2 diabetes 
      mellitus (T2DM), sleep obstructive apnea syndrome, and arthropathy) were also 
      described. Results  88 patients (mean age 46.1+/-12.3 years, 69.3 % female) 
      underwent ESG. Mean body mass index (BMI) at baseline was 39.40 +/- 4.69 kg/m(2). At 
      1 year, %TBWL was 17.36 +/- 6.09 % (%EWL 46.41+/-20.6 %) with TBWL > 10 % in 95.5 % 
      of patients (EWL > 25 % in 94.3 % of patients). According to pattern, there were 
      no differences in %TBWL but there were in %EWL (43.7 +/- 20.4 %, 59.8 +/- 18.9 % and 
      45.4 +/- 14.9 % in TBp, Lp and TMp patterns, respectively) ( P  = 0.034). No 
      differences were found related to number of sutures (mean 5.2 +/- 0.73, r = 4 - 7) 
      or stitches (mean 27.4 +/- 6.50, r = 18 - 50) applied. Forty-three of 72 (59.7 %) 
      major comorbidities were resolved. No serious adverse events were observed with 
      any pattern. Conclusions  ESG is an effective procedure at 12-month follow-up for 
      weight loss and comorbidity resolution. All three analyzed patterns are safe and 
      effective without differences in %TBWL, but there was a slight increase in %EWL 
      in Lp, regardless of the number of sutures or stitches applied.
CI  - The Author(s). This is an open access article published by Thieme under the terms 
      of the Creative Commons Attribution-NonDerivative-NonCommercial License, 
      permitting copying and reproduction so long as the original work is given 
      appropriate credit. Contents may not be used for commecial purposes, or adapted, 
      remixed, transformed or built upon. 
      (https://creativecommons.org/licenses/by-nc-nd/4.0/).
FAU - Espinet-Coll, E
AU  - Espinet-Coll E
AD  - Bariatric Endoscopy Unit. Dexeus University Hospital, Barcelona, Spain.
AD  - Bariatric Endoscopy Unit. Endosmedicina, Diagonal Clinic, Barcelona, Spain.
FAU - Nebreda-Duran, J
AU  - Nebreda-Duran J
AD  - Bariatric Endoscopy Unit. Endosmedicina, Diagonal Clinic, Barcelona, Spain.
FAU - Galvao-Neto, M
AU  - Galvao-Neto M
AD  - Endovitta, Sao Paolo, Brazil and Florida International University, Miami, United 
      States.
FAU - Bautista-Altamirano, C
AU  - Bautista-Altamirano C
AD  - Bariatric Endoscopy Unit. Avendano Clinic, Lima, Peru.
FAU - Diaz-Galan, P
AU  - Diaz-Galan P
AD  - Bariatric Endoscopy Unit. Dexeus University Hospital, Barcelona, Spain.
FAU - Gomez-Valero, J A
AU  - Gomez-Valero JA
AD  - Bariatric Endoscopy Unit. Dexeus University Hospital, Barcelona, Spain.
FAU - Vila-Lolo, C
AU  - Vila-Lolo C
AD  - Bariatric Endoscopy Unit. Dexeus University Hospital, Barcelona, Spain.
FAU - Guirola-Puche, M A
AU  - Guirola-Puche MA
AD  - Bariatric Endoscopy Unit. Endosmedicina, Diagonal Clinic, Barcelona, Spain.
FAU - Fernandez-Huelamo, A
AU  - Fernandez-Huelamo A
AD  - Bariatric Endoscopy Unit. Endosmedicina, Diagonal Clinic, Barcelona, Spain.
FAU - Bargallo-Carulla, D
AU  - Bargallo-Carulla D
AD  - Bariatric Endoscopy Unit. Endosmedicina, Diagonal Clinic, Barcelona, Spain.
FAU - Juan-Creix Comamala, A
AU  - Juan-Creix Comamala A
AD  - Bariatric Endoscopy Unit. Dexeus University Hospital, Barcelona, Spain.
LA  - eng
PT  - Journal Article
DEP - 20200922
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC7508658
COIS- Competing interests Dr. Espinet-Coll and Dr. Galvao-Neto are consultants and have 
      received grants and personal fees from Apollo Endosurgery. Dr. Galvao-Neto has 
      received grants and personal fees from Fractyl Labs, GI Dynamics, GI Windows, 
      Olympus, Medtronic, and M.I. Tech.
EDAT- 2020/10/06 06:00
MHDA- 2020/10/06 06:01
PMCR- 2020/10/01
CRDT- 2020/10/05 06:22
PHST- 2020/04/24 00:00 [received]
PHST- 2020/06/12 00:00 [accepted]
PHST- 2020/10/05 06:22 [entrez]
PHST- 2020/10/06 06:00 [pubmed]
PHST- 2020/10/06 06:01 [medline]
PHST- 2020/10/01 00:00 [pmc-release]
AID - 10.1055/a-1221-9835 [doi]
PST - ppublish
SO  - Endosc Int Open. 2020 Oct;8(10):E1349-E1358. doi: 10.1055/a-1221-9835. Epub 2020 
      Sep 22.