PMID- 33016204 OWN - NLM STAT- MEDLINE DCOM- 20211115 LR - 20211115 IS - 1552-6844 (Electronic) IS - 1545-9683 (Linking) VI - 34 IP - 11 DP - 2020 Nov TI - Improvement of the Upper Extremity at the Subacute Stage Poststroke: Does Hand Dominance Play a Role? PG - 1030-1037 LID - 10.1177/1545968320962502 [doi] AB - BACKGROUND: The impact of hand dominance on the expected (motor and functional ability and daily use) improvement of the affected upper extremity (UE) in subacute stroke has not yet been investigated. OBJECTIVES: To compare between the affected dominant and affected nondominant UE (1) on rehabilitation admission (T1) for motor and sensory abilities, functional ability, and daily use and (2) 6 weeks poststroke onset (T2) and the UE recovery between T1 and T2 regarding percent change, improvement effect size, and percent of participants achieving minimal clinical important difference (MCID). METHODS: Multicenter longitudinal study. RESULTS: Thirty-eight participants with affected dominant and 51 participants with affected nondominant UE were recruited. On T1 and T2, between-group differences were not seen for all UE variables. Significant improvement in the motor and functional ability, daily use, and perceived recovery between T1 and T2 were seen for the affected dominant (z = -3.01 to -4.13, P < .01) and nondominant UEs (z = -4.59 to -5.32, P < .01). Effect size improvement values were moderate and large in the affected dominant and nondominant UE (respectively). In addition, 14% to 40% of the participants in both UEs achieved MCID. CONCLUSIONS: Significant and similar clinical meaningfulness in UE improvement can be expected during subacute rehabilitation; however, improvement magnitude and percent improvement is different for the UE domains of the affected dominant and the affected nondominant UEs. These findings highlight the distinct roles of the dominant and nondominant hands during bimanual daily activities, which can guide clinicians during stroke rehabilitation. FAU - Hmaied Assadi, Samar AU - Hmaied Assadi S AD - Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel. FAU - Feige Gross-Nevo, Revital AU - Feige Gross-Nevo R AD - Beit Rivka Geriatric Rehabilitation Center, Petach Tikva, Israel. FAU - Dudkiewicz, Israel AU - Dudkiewicz I AUID- ORCID: 0000-0003-1578-930X AD - Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel. AD - Sheba Medical Center, Tel Hashomer, Israel. FAU - Barel, Haim AU - Barel H AD - Bayit Balev Rehabilitation Center, Maccabi Health Care Services Group, Bat-Yam, Israel. FAU - Rand, Debbie AU - Rand D AUID- ORCID: 0000-0001-6410-2389 AD - Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel. LA - eng PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't DEP - 20201005 PL - United States TA - Neurorehabil Neural Repair JT - Neurorehabilitation and neural repair JID - 100892086 SB - IM MH - Aged MH - Aged, 80 and over MH - Female MH - *Functional Laterality MH - Hand MH - Humans MH - Longitudinal Studies MH - Male MH - Stroke/*physiopathology MH - *Stroke Rehabilitation MH - Treatment Outcome MH - Upper Extremity/*physiopathology OTO - NOTNLM OT - daily use OT - hand function OT - handedness OT - rehabilitation OT - stroke EDAT- 2020/10/06 06:00 MHDA- 2021/11/16 06:00 CRDT- 2020/10/05 08:41 PHST- 2020/10/06 06:00 [pubmed] PHST- 2021/11/16 06:00 [medline] PHST- 2020/10/05 08:41 [entrez] AID - 10.1177/1545968320962502 [doi] PST - ppublish SO - Neurorehabil Neural Repair. 2020 Nov;34(11):1030-1037. doi: 10.1177/1545968320962502. Epub 2020 Oct 5.