PMID- 33027626 OWN - NLM STAT- MEDLINE DCOM- 20210419 LR - 20210419 IS - 1096-0953 (Electronic) IS - 0013-9351 (Linking) VI - 192 DP - 2021 Jan TI - Greenness surrounding schools and adiposity in children and adolescents: Findings from a national population-based study in China. PG - 110289 LID - S0013-9351(20)31186-5 [pii] LID - 10.1016/j.envres.2020.110289 [doi] AB - BACKGROUND: Previous studies have indicated that exposure to green space may benefit human health. However, the available evidence concerning the effects of greenness, especially school-based greenness, on pediatric obesity is scarce. OBJECTIVE: To explore the association between school-based greenness and adiposity in children and adolescents in China. METHOD: We conducted a nationwide cross-sectional study of 56,620 children and adolescents (aged 6-18 years) in seven provinces/municipalities across China. School-based greenness was assessed using satellite-derived Normalized Difference Vegetation Index (NDVI) and Soil Adjusted Vegetation Index (SAVI) within 100-, 500-, and 1000-m circular buffers around each school's address. Generalized linear mixed regression models were used to estimate associations of greenness with BMI z-scores (zBMI), waist circumference, and prevalent overweight/obesity. We also explored the potential mediating role of ambient air pollution and physical activity in the greenness-adiposity associations. RESULT: In the adjusted model, an IQR increase in NDVI(-1000m) was associated with lower zBMI (beta: -0.11, 95% confidence interval[CI]: -0.13,-0.09) and waist circumference (beta: -0.64, 95%CI: -0.78,-0.50). Consistently, an IQR increase in NDVI(-100m), NDVI(-500m), NDVI(-1000m) was associated with 7-20% lower odds of overweight/obesity in the adjusted models. Air pollutants mediated 6.5-29.1% of the association between greenness and zBMI. No significant mediation effect was observed for physical activity. CONCLUSION: Higher school-based greenness levels were associated with lower zBMI, waist circumference, and lower odds of overweight and obesity in children and adolescents. Ambient air pollutants may partially mediate the greenness-adiposity associations. CI - Copyright (c) 2020 Elsevier Inc. All rights reserved. FAU - Bao, Wen-Wen AU - Bao WW AD - Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China. FAU - Yang, Bo-Yi AU - Yang BY AD - Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Guangdong Provincial Engineering Technology Research Center of Environmental and Health Risk Assessment, Department of Preventive Medicine, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China. FAU - Zou, Zhi-Yong AU - Zou ZY AD - Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, 100191, China. FAU - Ma, Jun AU - Ma J AD - Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, 100191, China. FAU - Jing, Jin AU - Jing J AD - Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China. FAU - Wang, Hai-Jun AU - Wang HJ AD - Department of Maternal and Child Health, School of Public Health, Peking University, Beijing, 100191, China. FAU - Luo, Jia-You AU - Luo JY AD - Department of Maternal and Child Health, School of Public Health, Central South University, Changsha, 410078, China. FAU - Zhang, Xin AU - Zhang X AD - School of Public Health, Tianjin Medical University, Tianjin, 300070, China. FAU - Luo, Chun-Yan AU - Luo CY AD - Shanghai Municipal Center for Disease Control and Prevention, Shanghai Institute of Preventive Medicine, Shanghai, 200336, China. FAU - Wang, Hong AU - Wang H AD - Department of Maternal and Child Health, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China. FAU - Zhao, Hai-Ping AU - Zhao HP AD - School of Public Health and Management, Ningxia Medical University, Ningxia, 750004, China. FAU - Pan, De-Hong AU - Pan DH AD - Liaoning Health Supervision Bureau, Shenyang, 110005, China. FAU - Gui, Zhao-Huan AU - Gui ZH AD - Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China. FAU - Zhang, Jing-Shu AU - Zhang JS AD - Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China. FAU - Guo, Yu-Ming AU - Guo YM AD - Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, 3004, Australia. FAU - Ma, Ying-Hua AU - Ma YH AD - Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, 100191, China. Electronic address: yinghuama@bjmu.edu.cn. FAU - Dong, Guang-Hui AU - Dong GH AD - Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Guangdong Provincial Engineering Technology Research Center of Environmental and Health Risk Assessment, Department of Preventive Medicine, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China. Electronic address: donggh5@mail.sysu.edu.cn. FAU - Chen, Ya-Jun AU - Chen YJ AD - Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China. Electronic address: chenyj68@mail.sysu.edu.cn. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20201004 PL - Netherlands TA - Environ Res JT - Environmental research JID - 0147621 SB - IM MH - *Adiposity MH - Adolescent MH - Child MH - China/epidemiology MH - Cities MH - Cross-Sectional Studies MH - Humans MH - *Pediatric Obesity/epidemiology MH - Schools OTO - NOTNLM OT - Cross-sectional study OT - Green space OT - Mediating effect OT - Obesity OT - Overweight EDAT- 2020/10/08 06:00 MHDA- 2021/04/20 06:00 CRDT- 2020/10/07 20:05 PHST- 2020/07/07 00:00 [received] PHST- 2020/09/23 00:00 [revised] PHST- 2020/09/28 00:00 [accepted] PHST- 2020/10/08 06:00 [pubmed] PHST- 2021/04/20 06:00 [medline] PHST- 2020/10/07 20:05 [entrez] AID - S0013-9351(20)31186-5 [pii] AID - 10.1016/j.envres.2020.110289 [doi] PST - ppublish SO - Environ Res. 2021 Jan;192:110289. doi: 10.1016/j.envres.2020.110289. Epub 2020 Oct 4.