PMID- 33028670
OWN - NLM
STAT- MEDLINE
DCOM- 20210629
LR  - 20210629
IS  - 1468-201X (Electronic)
IS  - 1355-6037 (Linking)
VI  - 106
IP  - 24
DP  - 2020 Dec
TI  - Novel bradycardia pacing strategies.
PG  - 1883-1889
LID - 10.1136/heartjnl-2020-316849 [doi]
AB  - The adverse effects of ventricular dyssynchrony induced by right ventricular (RV) 
      pacing has led to alternative pacing strategies, such as biventricular, His 
      bundle (HBP), LV septal (LVSP) and left bundle branch pacing (LBBP). Given the 
      overlap, LVSP and LBBP are also collectively referred to as left bundle branch 
      area pacing (LBBAP). Although among these alternative pacing sites HBP is 
      theoretically the ideal strategy as it maintains a physiological ventricular 
      activation, its application requires more skills and is associated with the most 
      complications. LBBAP, where the ventricular pacing lead is advanced through the 
      interventricular septum to its left side, creates ventricular activation that is 
      only slightly more dyssynchronous. Preliminary studies have shown that LBBAP is 
      feasible, safe and encounters less limitations than HBP. Further studies are 
      needed to differentiate between LVSP and LBBP with regard to acute functional and 
      long-term clinical outcome.
CI  - (c) Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Heckman, Luuk
AU  - Heckman L
AD  - Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), 
      Maastricht University, The Netherlands.
FAU - Vijayaraman, Pugazhendhi
AU  - Vijayaraman P
AUID- ORCID: 0000-0003-2230-100X
AD  - Geisinger Heart Institute, Geisinger Commonwealth School of Medicine, Wilkes 
      Barre, Pennsylvania, USA.
FAU - Luermans, Justin
AU  - Luermans J
AD  - Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), 
      Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
AD  - Department of Cardiology, Radboud University Medical Centre (Radboudumc), 
      Nijmegen, The Netherlands.
FAU - Stipdonk, Antonius M W
AU  - Stipdonk AMW
AD  - Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), 
      Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
FAU - Salden, Floor
AU  - Salden F
AD  - Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), 
      Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
FAU - Maass, Alexander H
AU  - Maass AH
AUID- ORCID: 0000-0002-7936-360X
AD  - Department of Cardiology, University of Groningen, University Medical Centre 
      Groningen (UMCG), The Netherlands.
FAU - Prinzen, Frits W
AU  - Prinzen FW
AD  - Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), 
      Maastricht University, The Netherlands.
FAU - Vernooy, Kevin
AU  - Vernooy K
AUID- ORCID: 0000-0001-8539-3365
AD  - Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), 
      Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands 
      kevin.vernooy@mumc.nl.
AD  - Department of Cardiology, Radboud University Medical Centre (Radboudumc), 
      Nijmegen, The Netherlands.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20201007
PL  - England
TA  - Heart
JT  - Heart (British Cardiac Society)
JID - 9602087
SB  - IM
MH  - Bradycardia/physiopathology/*therapy
MH  - Bundle of His/*physiopathology
MH  - Cardiac Pacing, Artificial/*standards
MH  - Electrocardiography
MH  - Heart Rate/*physiology
MH  - Humans
MH  - *Practice Guidelines as Topic
OTO - NOTNLM
OT  - bradyarrhythmias
OT  - pacemakers
COIS- Competing interests: PV: fellowship support and research grant from Medtronic; 
      honorarium from Abbott, Biotronik, Boston Scientific and Medtronic. Patent 
      pending for His delivery tool. FWP: research grants from Medtronic, Abbott, 
      MicroPort CRM, Biotronik. KV: research grants from Medtronic, Abbott and 
      Biotronik, consultancy agreement with Medtronic. AHM: lecture fees from Abbott. 
      TvS: lecture fees from Abbott. JL: consultancy agreement Medtronic.
EDAT- 2020/10/09 06:00
MHDA- 2021/06/30 06:00
CRDT- 2020/10/08 05:27
PHST- 2020/06/17 00:00 [received]
PHST- 2020/08/08 00:00 [revised]
PHST- 2020/08/30 00:00 [accepted]
PHST- 2020/10/09 06:00 [pubmed]
PHST- 2021/06/30 06:00 [medline]
PHST- 2020/10/08 05:27 [entrez]
AID - heartjnl-2020-316849 [pii]
AID - 10.1136/heartjnl-2020-316849 [doi]
PST - ppublish
SO  - Heart. 2020 Dec;106(24):1883-1889. doi: 10.1136/heartjnl-2020-316849. Epub 2020 
      Oct 7.