PMID- 33029840
OWN - NLM
STAT- MEDLINE
DCOM- 20210825
LR  - 20210825
IS  - 1941-2452 (Electronic)
IS  - 0884-5336 (Linking)
VI  - 35
IP  - 6
DP  - 2020 Dec
TI  - The Association of Grip Strength, Body Mass Index, and Lung Function in Youth 
      with Cystic Fibrosis.
PG  - 1110-1118
LID - 10.1002/ncp.10583 [doi]
AB  - Compared with body mass index (BMI), lean body mass and fat-free mass are 
      strongly associated with lung function in children and adolescents with cystic 
      fibrosis (CF). Methods of measuring body composition in youth with CF are often 
      unreliable, expensive, or not clinically feasible. Grip strength (GS), a measure 
      of muscle function, is used as a surrogate for muscle mass and is an indicator of 
      nutrition status. This quality improvement project explored the feasibility of 
      measuring GS in medically stable youth with CF, aged 6-21 years. A total 361 GS 
      measurements were performed by using a digital hand dynamometer in youth from a 
      single CF center. Using reference tables that were created for this project by 
      merging data from the 2011-2012 and 2013-2014 National Health and Nutrition 
      Examination Surveys, youth with CF were found to be weaker than age- and 
      gender-matched peers, even when controlled for differences in size. A positive 
      association (P < .001) was found between GS percentile and lung function, as 
      measured by forced expiratory volume in 1 second percent predicted (FEV1pp). 
      Statistical analysis revealed that both BMI percentile and absolute GS (AGS) 
      percentile were positively associated with FEV1pp and with each other, primarily 
      at the lower levels of BMI percentile (<50%) and AGS percentile (<50%). GS may 
      provide a reliable, less expensive, and clinically feasible alternative to body 
      composition measurements in monitoring nutrition status in youth with CF, 
      especially in youth whose BMI is in the <50th percentile.
CI  - (c) 2020 American Society for Parenteral and Enteral Nutrition.
FAU - Bouma, Sandra F
AU  - Bouma SF
AUID- ORCID: 0000-0002-3573-7067
AD  - Division of Pediatric Pulmonology, Nutrition Services, Michigan Medicine, Ann 
      Arbor, Michigan, USA.
FAU - Iwanicki, Courtney
AU  - Iwanicki C
AD  - Division of Pediatric Pulmonology, Nutrition Services, Michigan Medicine, Ann 
      Arbor, Michigan, USA.
FAU - McCaffery, Harlan
AU  - McCaffery H
AD  - Center for Human Growth and Development, University of Michigan, Ann Arbor, 
      Michigan, USA.
FAU - Nasr, Samya Z
AU  - Nasr SZ
AD  - Department of Pediatrics, Division of Pediatric Pulmonology, Michigan Medicine, 
      Ann Arbor, Michigan, USA.
LA  - eng
PT  - Journal Article
DEP - 20201007
PL  - United States
TA  - Nutr Clin Pract
JT  - Nutrition in clinical practice : official publication of the American Society for 
      Parenteral and Enteral Nutrition
JID - 8606733
SB  - IM
MH  - Adolescent
MH  - Body Mass Index
MH  - Child
MH  - *Cystic Fibrosis/complications/diagnosis
MH  - Forced Expiratory Volume
MH  - *Hand Strength
MH  - Humans
MH  - *Lung/physiopathology
OTO - NOTNLM
OT  - body mass index
OT  - cystic fibrosis
OT  - grip strength
OT  - lung function
OT  - nutrition assessment
EDAT- 2020/10/09 06:00
MHDA- 2021/08/26 06:00
CRDT- 2020/10/08 05:36
PHST- 2020/05/19 00:00 [received]
PHST- 2020/09/13 00:00 [accepted]
PHST- 2020/10/09 06:00 [pubmed]
PHST- 2021/08/26 06:00 [medline]
PHST- 2020/10/08 05:36 [entrez]
AID - 10.1002/ncp.10583 [doi]
PST - ppublish
SO  - Nutr Clin Pract. 2020 Dec;35(6):1110-1118. doi: 10.1002/ncp.10583. Epub 2020 Oct 
      7.