PMID- 33031180
OWN - NLM
STAT- MEDLINE
DCOM- 20211015
LR  - 20211015
IS  - 1473-5598 (Electronic)
IS  - 0263-6352 (Linking)
VI  - 39
IP  - 3
DP  - 2021 Mar 1
TI  - Isolated diastolic hypertension as defined by the 2017 American College of 
      Cardiology/American Heart Association blood pressure guideline and incident 
      cardiovascular events in Chinese.
PG  - 519-525
LID - 10.1097/HJH.0000000000002659 [doi]
AB  - OBJECTIVE: The new arterial hypertension guidelines by the 2017 American College 
      of Cardiology (ACC)/American Heart Association (AHA) changed the definition of 
      isolated diastolic hypertension (IDH). We assessed and compared in a Chinese 
      population the IDH prevalence, newly defined by the 2017 ACC/AHA guidelines 
      versus the former definition by the Joint National Committee 7 (JNC7) criteria, 
      and examined longitudinal associations of IDH with cardiovascular disease (CVD) 
      outcomes. METHODS: The prospective community-based Kailuan Study included 
      participants aged 18-98 years who underwent a detailed medical examination at 
      baseline in 2006/2007 and who were biennially re-examined till 2017. History of 
      antihypertensive medication at baseline was an exclusion criterion. RESULTS: The 
      study population consisted of 87 346 individuals (mean age: 50.9 years; range: 
      18-98 years). Prevalence of IDH was 7.79% [95% confidence interval (CI): 7.62, 
      7.97] by JNC7 guidelines and 24.72% (95% CI: 24.43, 25.01) by 2017 ACC/AHA 
      criteria [difference: 19.93% (95% CI: 16.81, 17.04)]. Applying the 2017 ACC/AHA 
      guidelines, the prevalence of IDH-recommended antihypertensive therapy was 7.73% 
      (95% CI: 7.55, 7.90). In multivariable analysis, IDH by JNC7 criteria was 
      significantly associated with incident myocardial infarction [n = 93 events; 
      hazard ratio: 1.30 (95 CI: 1.02, 1.66)], cerebral hemorrhage [n = 73 events; 
      hazard ratio: 1.79 (95% CI: 1.35, 2.38)], and total CVD [n = 373 events; hazard 
      ratio: 1.15 (95% CI: 1.02, 1.30)], when compared with normotension. IDH based on 
      2017 ACC/AHA guidelines was associated with incident cerebral hemorrhage [n = 129 
      events; hazard ratio: 1.47 (95% CI: 1.12, 1.94)] and total CVD [n = 828 events; 
      hazard ratio: 1.13 (95% CI: 1.02, 1.26)]. CONCLUSION: In this adult Chinese 
      community, 2017 ACC/AHA-defined IDH was associated with the incidence of cerebral 
      hemorrhage and total CVD, and as compared with JNC7-defined IDH, it was more 
      prevalent.
CI  - Copyright (c) 2020 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Wu, Shouling
AU  - Wu S
AD  - Department of Cardiology, Kailuan General Hospital, North China University of 
      Science and Technology, Tangshan, China.
FAU - Ji, Chunpeng
AU  - Ji C
AD  - Department of Cardiology, Kailuan General Hospital, North China University of 
      Science and Technology, Tangshan, China.
FAU - Shi, Jihong
AU  - Shi J
AD  - Department of Cardiology, Kailuan General Hospital, North China University of 
      Science and Technology, Tangshan, China.
FAU - Chen, Shuohua
AU  - Chen S
AD  - Department of Cardiology, Kailuan General Hospital, North China University of 
      Science and Technology, Tangshan, China.
FAU - Huang, Zhe
AU  - Huang Z
AD  - Department of Cardiology, Kailuan General Hospital, North China University of 
      Science and Technology, Tangshan, China.
FAU - Jonas, Jost B
AU  - Jonas JB
AD  - Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, 
      Mannheim, Germany.
AD  - Institute of Molecular and Clinical Ophthalmology, Basel, Switzerland.
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - J Hypertens
JT  - Journal of hypertension
JID - 8306882
SB  - IM
MH  - Adult
MH  - American Heart Association
MH  - Blood Pressure
MH  - *Cardiology
MH  - China/epidemiology
MH  - Humans
MH  - *Hypertension/diagnosis/drug therapy/epidemiology
MH  - Middle Aged
MH  - Prevalence
MH  - Prospective Studies
MH  - Risk Factors
MH  - United States/epidemiology
EDAT- 2020/10/09 06:00
MHDA- 2021/10/16 06:00
CRDT- 2020/10/08 17:12
PHST- 2020/10/09 06:00 [pubmed]
PHST- 2021/10/16 06:00 [medline]
PHST- 2020/10/08 17:12 [entrez]
AID - 00004872-202103000-00019 [pii]
AID - 10.1097/HJH.0000000000002659 [doi]
PST - ppublish
SO  - J Hypertens. 2021 Mar 1;39(3):519-525. doi: 10.1097/HJH.0000000000002659.