PMID- 33033816 OWN - NLM STAT- MEDLINE DCOM- 20210517 LR - 20210517 IS - 1364-548X (Electronic) IS - 1359-7345 (Linking) VI - 56 IP - 80 DP - 2020 Oct 14 TI - One-pot synthesis of template-free hollow anisotropic CaCO(3) structures: towards inorganic shape-mimicking drug delivery systems. PG - 11969-11972 LID - 10.1039/d0cc05502f [doi] AB - A major obstacle in the introduction of nanoformulated drugs has been the fact that the shape of the drug delivery systems (DDSs) - the most important parameter driven by the nature of viruses and bacteria - remains almost out-of-scope in artificial systems. Here we propose a potential solution for this problem by developing a template-free approach for the formulation of hollow bacteria-like CaCO(3)-based pH-sensitive DDSs with controllable anisotropy and click-release behavior. FAU - Serov, Nikita AU - Serov N AD - International Institute "Solution Chemistry of Advanced Materials and Technologies" (SCAMT), 9, Lomonosova str., Saint-Petersburg, 191002, Russian Federation. vinogradov@scamt-itmo.ru. FAU - Darmoroz, Darina AU - Darmoroz D FAU - Lokteva, Alina AU - Lokteva A FAU - Chernyshov, Ivan AU - Chernyshov I FAU - Koshel, Elena AU - Koshel E FAU - Vinogradov, Vladimir AU - Vinogradov V LA - eng PT - Journal Article DEP - 20200907 PL - England TA - Chem Commun (Camb) JT - Chemical communications (Cambridge, England) JID - 9610838 RN - 0 (Drug Carriers) RN - 0 (Fluorescent Dyes) RN - H0G9379FGK (Calcium Carbonate) RN - I38ZP9992A (Magnesium) RN - TPY09G7XIR (Fluorescein) SB - IM MH - Anisotropy MH - Biomimetic Materials/*chemistry MH - Calcium Carbonate/*chemistry MH - Click Chemistry MH - Drug Carriers/*chemistry MH - Drug Compounding MH - Drug Liberation MH - Escherichia coli/chemistry MH - Fluorescein/chemistry MH - Fluorescent Dyes/chemistry MH - Hydrogen-Ion Concentration MH - Magnesium/chemistry MH - Microspheres MH - Porosity EDAT- 2020/10/10 06:00 MHDA- 2021/05/18 06:00 CRDT- 2020/10/09 05:39 PHST- 2020/10/10 06:00 [pubmed] PHST- 2021/05/18 06:00 [medline] PHST- 2020/10/09 05:39 [entrez] AID - 10.1039/d0cc05502f [doi] PST - ppublish SO - Chem Commun (Camb). 2020 Oct 14;56(80):11969-11972. doi: 10.1039/d0cc05502f. Epub 2020 Sep 7.