PMID- 33046165
OWN - NLM
STAT- MEDLINE
DCOM- 20210907
LR  - 20210907
IS  - 1435-8115 (Electronic)
IS  - 1431-9276 (Linking)
VI  - 26
IP  - 6
DP  - 2020 Dec
TI  - Histological and Ultrastructural Studies of the Unique Hemopoietic-Endocrine 
      Organ of the Grass Carp, Ctenopharyngodon idella (Valenciennes, 1844).
PG  - 1264-1273
LID - 10.1017/S1431927620024575 [doi]
AB  - Specific features of the immunohistochemical and ultrastructural organization of 
      the hemopoietic head-kidney (HK) in adult Ctenopharyngodon idella (Valenciennes, 
      1844) were investigated using light and transmission electron microscopy. The HK 
      of grass carp possessed all developmental stages of leucocytes and erythrocytes, 
      as well as dendritic cells and epithelial reticular cells. The rodlet cells were 
      expressed alpha-smooth muscle actin (SMA). In addition, macrophages were the most 
      numerous cells in the HK, which aggregated into structures called 
      melanomacrophage centers (MMCs). On contrary, the chromaffin and interrenal cells 
      (ICs) were mixed and organized into large anastomosing cords, which lined the 
      posterior cardinal veins of the HK, and associated with many blood capillaries. 
      The ICs displayed the characteristic features of steroid-producing cells. Three 
      types of chromaffin cells: adrenaline, noradrenaline, and small 
      granule-containing cells were observed in the HK. Glial fibrillary acidic protein 
      (GFAP)-positive sustentacular cells were marked among the chromaffin cells. 
      Hemopoietic cells, immune cells, MMCs, rodlet cells, in addition to three types 
      of chromaffin cells and one type of interrenal cells in the HK were correlated 
      with the functional significance of the fish concerned.
FAU - Mokhtar, Doaa M
AU  - Mokhtar DM
AUID- ORCID: 0000-0001-7975-3926
AD  - Department of Anatomy and Histology, Faculty of Veterinary Medicine, Assiut 
      University, Assiut71526, Egypt.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Microsc Microanal
JT  - Microscopy and microanalysis : the official journal of Microscopy Society of 
      America, Microbeam Analysis Society, Microscopical Society of Canada
JID - 9712707
SB  - IM
MH  - Animals
MH  - *Carps
MH  - *Chromaffin Cells
MH  - Head Kidney
MH  - Macrophages
MH  - Microscopy, Electron, Transmission
OTO - NOTNLM
OT  - TEM
OT  - hemopoietic cells
OT  - immune cells
OT  - immunohistochemistry
OT  - interrenal cells
OT  - melanomacrophage
EDAT- 2020/10/14 06:00
MHDA- 2021/09/08 06:00
CRDT- 2020/10/13 05:28
PHST- 2020/10/14 06:00 [pubmed]
PHST- 2021/09/08 06:00 [medline]
PHST- 2020/10/13 05:28 [entrez]
AID - S1431927620024575 [pii]
AID - 10.1017/S1431927620024575 [doi]
PST - ppublish
SO  - Microsc Microanal. 2020 Dec;26(6):1264-1273. doi: 10.1017/S1431927620024575.