PMID- 33046261 OWN - NLM STAT- MEDLINE DCOM- 20210806 LR - 20210806 IS - 0035-3787 (Print) IS - 0035-3787 (Linking) VI - 177 IP - 1-2 DP - 2021 Jan-Feb TI - MRI characteristics of MOG-Ab associated disease in adults: An update. PG - 39-50 LID - S0035-3787(20)30679-2 [pii] LID - 10.1016/j.neurol.2020.06.016 [doi] AB - Our knowledge of the radiological spectrum of myelin oligodendrocyte glycoprotein antibody associated disease (MOGAD) is growing rapidly. An update on the radiological features of the disease, and its evolution is thus necessary. Magnetic resonance imaging (MRI) has an increasingly important role in the differential diagnosis of MOGAD particularly from aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-NMOSD), and multiple sclerosis (MS). Differentiating these conditions is of prime importance because the management is different between the three inflammatory diseases, and thus could prevent further attack-related disability. Therefore, identifying the MRI features suggestive of MOGAD has diagnostic and prognostic implications. We herein review optic nerve, spinal cord and the brain MRI findings from MOGAD adult patients, and compare them to AQP4-NMOSD and MS. CI - Copyright (c) 2020 Elsevier Masson SAS. All rights reserved. FAU - Shor, N AU - Shor N AD - Department of Neuroradiology, Pitie Salpetriere Hospital, APHP, 47-83, boulevard de l'Hopital, 75013 Paris, France. Electronic address: natalia.shor@aphp.fr. FAU - Deschamps, R AU - Deschamps R AD - Department of Neurology, Hopital Fondation Adolphe de Rothschild Paris Paris, France. FAU - Cobo Calvo, A AU - Cobo Calvo A AD - Centre de reference des maladies inflammatoires rares du cerveau et de la moelle (MIRCEM)- Service de neurologie, sclerose en plaques, pathologies de la myeline et neuro-inflammation-Hopital Neurologique Pierre Wertheimer Hospices Civils de Lyon, 6977 Lyon, France. FAU - Maillart, E AU - Maillart E AD - Department of Neurology, Pitie-Salpetriere Hospital, APHP, Paris, France. FAU - Zephir, H AU - Zephir H AD - Department of Neurology, U 1172,CRC-SEP, University Hospital of Lille, Lille, France. FAU - Ciron, J AU - Ciron J AD - Department of Neurology, University Hospital of Purpan, Toulouse, France. FAU - Papeix, C AU - Papeix C AD - Department of Neurology, Pitie-Salpetriere Hospital, APHP, Paris, France. FAU - Durand-Dubief, F AU - Durand-Dubief F AD - Centre de reference des maladies inflammatoires rares du cerveau et de la moelle (MIRCEM)- Service de neurologie, sclerose en plaques, pathologies de la myeline et neuro-inflammation-Hopital Neurologique Pierre Wertheimer Hospices Civils de Lyon, 6977 Lyon, France. FAU - Ruet, A AU - Ruet A AD - Department of Neurology, Bordeaux University Hospital, Bordeaux, France. FAU - Ayrignac, X AU - Ayrignac X AD - Department of Neurology, Montpellier University Hospital, Montpellier, France. FAU - Cohen, M AU - Cohen M AD - Service de Neurologie, Universite Cote d'Azur, Hopital Pasteur 2, Nice University Hospital, Nice, France. FAU - Deiva, K AU - Deiva K AD - National Referral Center for Neuro-Inflammatory Diseases and Pediatric Neurology Department, Kremlin-Bicetre Hospital, Kremlin-Bicetre, France. FAU - Laplaud, D AU - Laplaud D AD - Department of Neurology, Nantes University Hospital, Nantes, France. FAU - Bourre, B AU - Bourre B AD - Department of Neurology, Rouen University Hospital, Rouen, France. FAU - Audoin, B AU - Audoin B AD - Department of Neurology, Pole de Neurosciences Cliniques, APHM, Aix Marseille University, Timone Hospital, Marseille, France. FAU - Collongues, N AU - Collongues N AD - Department of Neurology and Clinical Investigation Center, Strasbourg University Hospital, Strasbourg, France. FAU - Vukusic, S AU - Vukusic S AD - Centre de reference des maladies inflammatoires rares du cerveau et de la moelle (MIRCEM)- Service de neurologie, sclerose en plaques, pathologies de la myeline et neuro-inflammation-Hopital Neurologique Pierre Wertheimer Hospices Civils de Lyon, 6977 Lyon, France. FAU - Cotton, F AU - Cotton F AD - Department of Radiology, Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, 69310 Pierre-Benite, France. FAU - Marignier, R AU - Marignier R AD - Centre de reference des maladies inflammatoires rares du cerveau et de la moelle (MIRCEM)- Service de neurologie, sclerose en plaques, pathologies de la myeline et neuro-inflammation-Hopital Neurologique Pierre Wertheimer Hospices Civils de Lyon, 6977 Lyon, France. CN - NOMADMUS study group LA - eng PT - Journal Article PT - Review DEP - 20201010 PL - France TA - Rev Neurol (Paris) JT - Revue neurologique JID - 2984779R RN - 0 (Aquaporin 4) RN - 0 (Autoantibodies) RN - 0 (Myelin-Oligodendrocyte Glycoprotein) SB - IM MH - Adult MH - Aquaporin 4 MH - Autoantibodies MH - Humans MH - *Magnetic Resonance Imaging MH - Myelin-Oligodendrocyte Glycoprotein MH - Neuromyelitis Optica/diagnostic imaging OTO - NOTNLM OT - Aquaporin-4 OT - Imaging OT - Myelin Oligodendrocyte Glycoprotein OT - Myelitis OT - Neuromyelitis Optica OT - Optic neuritis EDAT- 2020/10/14 06:00 MHDA- 2021/08/07 06:00 CRDT- 2020/10/13 05:31 PHST- 2020/05/12 00:00 [received] PHST- 2020/06/20 00:00 [revised] PHST- 2020/06/23 00:00 [accepted] PHST- 2020/10/14 06:00 [pubmed] PHST- 2021/08/07 06:00 [medline] PHST- 2020/10/13 05:31 [entrez] AID - S0035-3787(20)30679-2 [pii] AID - 10.1016/j.neurol.2020.06.016 [doi] PST - ppublish SO - Rev Neurol (Paris). 2021 Jan-Feb;177(1-2):39-50. doi: 10.1016/j.neurol.2020.06.016. Epub 2020 Oct 10.