PMID- 33049602
OWN - NLM
STAT- MEDLINE
DCOM- 20210616
LR  - 20210616
IS  - 1872-6968 (Electronic)
IS  - 0303-8467 (Linking)
VI  - 199
DP  - 2020 Dec
TI  - Nomogram for predicting kyphotic deformity after laminoplasty in cervical 
      spondylotic myelopathy patients without preoperative kyphotic alignment.
PG  - 106284
LID - S0303-8467(20)30627-2 [pii]
LID - 10.1016/j.clineuro.2020.106284 [doi]
AB  - BACKGROUND: Kyphotic deformity occurrence after cervical laminoplasty is not 
      rare. Several studies have emphasized the development of postoperative kyphotic 
      deformity (PKD) will impair the functional outcome of cervical laminoplasty. We 
      established and validated a nomogram prediction model for kyphotic deformity 
      after laminoplasty in cervical spondylotic myelopathy patients (CSM) without 
      preoperative kyphotic alignment. METHODS: Preoperative and 1-year postoperative 
      data of 369 patients who underwent single-door cervical laminoplasty (SDCL) at 
      the author's hospital between July 2010 and February 2018 were collected. Using 
      the least absolute shrinkage and selection operator (LASSO) method, significant 
      parameters were selected to develop a nomogram prediction model. The prognostic 
      performance of the model was evaluated using concordance index (C-index) and 
      calibration curve. The discriminatory ability of the prediction model was 
      evaluated by the area under (receiver operating characteristic) curve (AUC). 
      RESULTS: Of the 369 patients, 31 developed PKD in 1 year after the surgery. Using 
      the LASSO regression, six significant variables composed the final model: age, 
      C2-7 sagittal vertical axis, C7 slope, C2-7 angle, flexion range of motion and 
      operation level were selected. The AUC of the nomogram was 0.771. The C-index for 
      the prediction nomogram was 0.771 (95 % CI: 0.672-0.870). The calibration curve 
      also indicated good consistency. CONCLUSION: A nomogram for predicting PKD after 
      SDCL was established and validated. For patients evaluated by this model with 
      predictive high risk of developing postoperative kyphosis, an alternative 
      approach to the subaxial cervical spine such as anterior surgery should be 
      considered.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Chen, Guoliang
AU  - Chen G
AD  - Department of Spine Surgery, The First Affiliated Hospital of Wenzhou Medical 
      University, Wenzhou, China.
FAU - Jia, Mengxian
AU  - Jia M
AD  - Department of Spine Surgery, The First Affiliated Hospital of Wenzhou Medical 
      University, Wenzhou, China.
FAU - Connel, Raymond Kobina
AU  - Connel RK
AD  - Department of Spine Surgery, The First Affiliated Hospital of Wenzhou Medical 
      University, Wenzhou, China.
FAU - Sheng, Yadong
AU  - Sheng Y
AD  - Department of Spine Surgery, The First Affiliated Hospital of Wenzhou Medical 
      University, Wenzhou, China.
FAU - Lin, Chaowei
AU  - Lin C
AD  - Department of Spine Surgery, The First Affiliated Hospital of Wenzhou Medical 
      University, Wenzhou, China.
FAU - Huang, Kelun
AU  - Huang K
AD  - Department of Spine Surgery, The First Affiliated Hospital of Wenzhou Medical 
      University, Wenzhou, China.
FAU - Ying, Jinwei
AU  - Ying J
AD  - Department of Spine Surgery, The First Affiliated Hospital of Wenzhou Medical 
      University, Wenzhou, China.
FAU - Teng, Honglin
AU  - Teng H
AD  - Department of Spine Surgery, The First Affiliated Hospital of Wenzhou Medical 
      University, Wenzhou, China. Electronic address: 907173102@qq.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20201007
PL  - Netherlands
TA  - Clin Neurol Neurosurg
JT  - Clinical neurology and neurosurgery
JID - 7502039
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cervical Vertebrae/*diagnostic imaging/surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Kyphosis/*diagnostic imaging/etiology
MH  - Laminoplasty/adverse effects/*trends
MH  - Male
MH  - Middle Aged
MH  - *Nomograms
MH  - Postoperative Complications/diagnostic imaging/etiology
MH  - Predictive Value of Tests
MH  - Preoperative Care/trends
MH  - Spinal Cord Diseases/*diagnostic imaging/surgery
MH  - Spondylosis/*diagnostic imaging/surgery
OTO - NOTNLM
OT  - Kyphotic deformity
OT  - Nomogram
OT  - Prediction model
OT  - Risk factors
OT  - Single-door cervical laminoplasty
EDAT- 2020/10/14 06:00
MHDA- 2021/06/17 06:00
CRDT- 2020/10/13 20:15
PHST- 2020/08/29 00:00 [received]
PHST- 2020/10/04 00:00 [revised]
PHST- 2020/10/04 00:00 [accepted]
PHST- 2020/10/14 06:00 [pubmed]
PHST- 2021/06/17 06:00 [medline]
PHST- 2020/10/13 20:15 [entrez]
AID - S0303-8467(20)30627-2 [pii]
AID - 10.1016/j.clineuro.2020.106284 [doi]
PST - ppublish
SO  - Clin Neurol Neurosurg. 2020 Dec;199:106284. doi: 10.1016/j.clineuro.2020.106284. 
      Epub 2020 Oct 7.