PMID- 33050555 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201103 IS - 2076-2615 (Print) IS - 2076-2615 (Electronic) IS - 2076-2615 (Linking) VI - 10 IP - 10 DP - 2020 Oct 11 TI - Effects of Optimal Carbohydrase Mixtures on Nutrient Digestibility and Digestible Energy of Corn- and Wheat-Based Diets in Growing Pigs. LID - 10.3390/ani10101846 [doi] LID - 1846 AB - This study aimed to evaluate the effects of optimal carbohydrase mixture (OCM) on macronutrients and amino acid digestibility and the digestible energy (DE) in growing pigs fed the corn-soybean meal-based diet (CSM) and the wheat-soybean meal-based diet (WSM). A total of 36 ileal-cannulated pigs (50.9 +/- 4.9 kg initial body weight) were allotted to four dietary treatments randomly, which included CSM and WSM diets, and two diets supplied with corresponding OCM. These OCMs were screened using an in vitro method from our previous study. After the five day adaptation period, fecal samples were collected from d six to seven, and ileal digesta samples were collected on d 8 and 10. Chromic oxide was added as an indigestible marker. The results show that the addition of OCM improved the apparent ileal digestibility (AID) of dry matter (DM), ash, carbohydrate (CHO), neutral detergent fiber, and gross energy (GE) and the apparent total tract digestibility (ATTD) of DM, CHO, and GE in CSM diet (p < 0.05), but reduced the apparent hindgut disappearance (AHD) of DM in CSM diet (p < 0.05). The ATTD of DM, crude protein (CP), ether extract (EE), ash, and GE and the AHD of DM, CP, EE, ash, CHO, and GE in WSM diet were improved by the OCM addition (p < 0.05), whereas the AID of DM, CP, ash, CHO, and GE were decreased (p < 0.05). The respective DE contents in CSM and WSM diets were increased from 15.45 to 15.74 MJ/kg and 15.03 to 15.49 MJ/kg under the effects of OCM (p < 0.05). Similar to the trend of AID of CP, the OCM addition increased the AID and standardized ileal digestibility (SID) of Ile, Thr, and Cys in CSM diet, but decreased the AID and SID of Ile, Phe, Thr, Val, Ala, Pro, Ser, and Tyr in WSM diet. In conclusion, the OCMs screened by an in vitro method could improve the total tract nutrient digestibility and DE for pigs fed corn-based diet or wheat-based diet but had inconsistent effects on the ileal digestibility of nutrients and energy. FAU - Zhang, Shunfen AU - Zhang S AUID- ORCID: 0000-0003-4895-9299 AD - State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China. FAU - Zhong, Ruqing AU - Zhong R AUID- ORCID: 0000-0003-0494-6699 AD - State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China. FAU - Gao, Lixiang AU - Gao L AD - State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China. FAU - Liu, Zhengqun AU - Liu Z AUID- ORCID: 0000-0002-5846-5498 AD - State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China. FAU - Chen, Liang AU - Chen L AD - State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China. FAU - Zhang, Hongfu AU - Zhang H AD - State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China. LA - eng GR - 2016-nybrc-03/Agricultural Research Outstanding Talents and Innovation Team/ GR - 2017ywf-zd-18/23/Fundamental Research Funds for Chinese Academy of Agricultural Sciences/ GR - ASTIP-IAS07/Agricultural Science and Technology Innovation Program/ PT - Journal Article DEP - 20201011 PL - Switzerland TA - Animals (Basel) JT - Animals : an open access journal from MDPI JID - 101635614 PMC - PMC7601035 OTO - NOTNLM OT - NSP component OT - carbohydrase OT - corn-soybean meal diet OT - digestibility OT - in vitro method OT - pig OT - wheat-soybean meal diet COIS- The authors declare no conflict of interest. EDAT- 2020/10/15 06:00 MHDA- 2020/10/15 06:01 PMCR- 2020/10/11 CRDT- 2020/10/14 01:04 PHST- 2020/08/24 00:00 [received] PHST- 2020/10/05 00:00 [revised] PHST- 2020/10/07 00:00 [accepted] PHST- 2020/10/14 01:04 [entrez] PHST- 2020/10/15 06:00 [pubmed] PHST- 2020/10/15 06:01 [medline] PHST- 2020/10/11 00:00 [pmc-release] AID - ani10101846 [pii] AID - animals-10-01846 [pii] AID - 10.3390/ani10101846 [doi] PST - epublish SO - Animals (Basel). 2020 Oct 11;10(10):1846. doi: 10.3390/ani10101846.