PMID- 33055459
OWN - NLM
STAT- MEDLINE
DCOM- 20211207
LR  - 20211214
IS  - 1347-4820 (Electronic)
IS  - 1346-9843 (Linking)
VI  - 84
IP  - 12
DP  - 2020 Nov 25
TI  - Pregnancy and Delivery in Patients With Repaired Congenital Heart Disease　- A 
      Retrospective Japanese Multicenter Study.
PG  - 2270-2274
LID - 10.1253/circj.CJ-19-1150 [doi]
AB  - BACKGROUND: Although advances in cardiac surgery have led to an increased number 
      of survivors with congenital heart disease (CHD), epidemiological data regarding 
      the pregnancies and deliveries of patients with repaired CHD are 
      scarce.Methods and Results:In this study, we retrospectively reviewed the 
      clinical outcomes of pregnancies and deliveries of women with repaired CHD. 
      Overall, 131 women with repaired CHD were enrolled and there were 269 gestations. 
      All patients were classified as New York Heart Association (NYHA) Class I or II. 
      The prevalence of cesarean sections was higher in patients with (CyCHD) than 
      without (AcyCHD) a past history of cyanosis (51% vs. 19%, respectively; P<0.01). 
      There were 228 offspring from 269 gestations and the most prevalent neonatal 
      complication was premature birth (10%), which was more frequent in the CyCHD than 
      AcyCHD group (15.7% vs. 5.6%, respectively; P<0.01). Five maternal cardiac 
      complications during delivery were observed only in the CyCHD group (8%); these 
      were classified as NYHA Class II and none was fatal. CONCLUSIONS: Delivery was 
      successful in most women with repaired CHD who were classified as NYHA Class I or 
      II, although some with CyCHD and NYHA Class II required more attention. Cesarean 
      sections were more common in the CyCHD than AcyCHD group, and CyCHD may be a 
      potential risk for preterm deliveries.
FAU - Takatsuki, Shinichi
AU  - Takatsuki S
AD  - Department of Pediatrics, Toho University Omori Medical Center.
FAU - Furutani, Yoshiyuki
AU  - Furutani Y
AD  - Pediatric Cardiology and Adult Congenital Cardiology, Tokyo Women's Medical 
      University.
FAU - Inai, Kei
AU  - Inai K
AD  - Pediatric Cardiology and Adult Congenital Cardiology, Tokyo Women's Medical 
      University.
FAU - Kobayashi, Tohru
AU  - Kobayashi T
AD  - Department of Development Strategy, Center for Clinical Research and Development, 
      National Center for Child Health and Development.
FAU - Inuzuka, Ryo
AU  - Inuzuka R
AD  - Department of Pediatrics, The University of Tokyo Hospital.
FAU - Uyeda, Tomomi
AU  - Uyeda T
AD  - Department of Pediatric Cardiology, Sakakibara Heart Institute.
FAU - Kamisago, Mitsuhiro
AU  - Kamisago M
AD  - Department of Pediatrics, Nippon Medical School Tama Nagayama Hospital.
FAU - Muneuchi, Jun
AU  - Muneuchi J
AD  - Department of Pediatric Cardiology, Japan Health Care Community Organization 
      Kyushu Hospital.
FAU - Kaneko, Masahide
AU  - Kaneko M
AD  - Department of Pediatric Cardiology, National Center for Child Health and 
      Development.
FAU - Misaki, Yasushi
AU  - Misaki Y
AD  - Department of Pediatric Cardiology, National Center for Child Health and 
      Development.
FAU - Ono, Hiroshi
AU  - Ono H
AD  - Department of Pediatric Cardiology, National Center for Child Health and 
      Development.
FAU - Kato, Hitoshi
AU  - Kato H
AD  - Department of Pediatric Cardiology, National Center for Child Health and 
      Development.
FAU - Shimada, Eriko
AU  - Shimada E
AD  - Pediatric Cardiology and Adult Congenital Cardiology, Tokyo Women's Medical 
      University.
FAU - Shinohara, Tokuko
AU  - Shinohara T
AD  - Pediatric Cardiology and Adult Congenital Cardiology, Tokyo Women's Medical 
      University.
FAU - Waki, Kenji
AU  - Waki K
AD  - Department of Pediatrics, Kurashiki Central Hospital.
FAU - Suda, Kenji
AU  - Suda K
AD  - Department of Pediatrics, Kurume University Hospital.
FAU - Hayabuchi, Yasunobu
AU  - Hayabuchi Y
AD  - Department of Pediatrics, Tokushima University Hospital.
FAU - Ohki, Hirotaka
AU  - Ohki H
AD  - Department of Cardiology, Tokyo Metropolitan Children's Medical Center.
FAU - Ishizaki, Reina
AU  - Ishizaki R
AD  - Department of Pediatrics, Keio University School of Medicine.
FAU - Maeda, Jun
AU  - Maeda J
AD  - Department of Cardiology, Tokyo Metropolitan Children's Medical Center.
AD  - Department of Pediatrics, Keio University School of Medicine.
FAU - Yamagishi, Hiroyuki
AU  - Yamagishi H
AD  - Department of Pediatrics, Keio University School of Medicine.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20201014
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
SB  - IM
MH  - Cesarean Section/statistics & numerical data
MH  - Female
MH  - *Heart Defects, Congenital/epidemiology/surgery
MH  - Humans
MH  - Japan/epidemiology
MH  - Pregnancy
MH  - *Pregnancy Complications, Cardiovascular/epidemiology
MH  - *Pregnancy Outcome
MH  - Premature Birth
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Adult congenital heart disease
OT  - Cesarean section
OT  - Premature
OT  - Tetralogy of Fallot
EDAT- 2020/10/16 06:00
MHDA- 2021/12/15 06:00
CRDT- 2020/10/15 17:22
PHST- 2020/10/16 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2020/10/15 17:22 [entrez]
AID - 10.1253/circj.CJ-19-1150 [doi]
PST - ppublish
SO  - Circ J. 2020 Nov 25;84(12):2270-2274. doi: 10.1253/circj.CJ-19-1150. Epub 2020 
      Oct 14.