PMID- 33059442
OWN - NLM
STAT- MEDLINE
DCOM- 20210322
LR  - 20210322
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 68
IP  - 43
DP  - 2020 Oct 28
TI  - Chromatographic Methods for Detection and Quantification of Carbendazim in Food.
PG  - 11880-11894
LID - 10.1021/acs.jafc.0c04225 [doi]
AB  - Carbendazim (CBZ), which is a fungicide widely used for the management of plant 
      diseases, has been detected in a number of food products. The negative effects of 
      CBZ to human health have stimulated the reduction of the maximum residue limits 
      (MRLs), and subsequently the development of reliable and sensitive detection 
      methods. Here, we are reviewing for the first time all reported chromatographic 
      methods for the detection and quantification of CBZ in food. Several techniques, 
      including liquid chromatography (LC), thin layer chromatography (TLC), micellar 
      electrokinetic chromatography (MEKC), and supercritical fluid chromatography 
      (SFC), were used for the separation and detection of CBZ, showing diverse 
      characteristics and sensitivity. Some methods allowed the specific determination 
      of CBZ, whereas other methods were successfully applied for the simultaneous 
      quantification of a huge number of pesticides. Most reported methods showed 
      limits of detection (LOD) and quantification (LOQ) lower than the MRLs. Relevant 
      efforts in the field have been directed toward the simplification and 
      optimization of the extraction steps prior to the chromatographic separation to 
      increase the recovery and reduce the matrix effects. In this Review, the 
      matrices, extraction procedures, and separation and detection parameters are 
      detailed and compared in order to provide new insights on the development of new 
      reliable methods for the detection of CBZ in food.
FAU - Wang, Su-Yan
AU  - Wang SY
AD  - School of Life Sciences, Nantong University, Nantong 226019, People's Republic of 
      China.
FAU - Shi, Xin-Chi
AU  - Shi XC
AD  - School of Life Sciences, Nantong University, Nantong 226019, People's Republic of 
      China.
FAU - Liu, Feng-Quan
AU  - Liu FQ
AUID- ORCID: 0000-0002-2029-0012
AD  - Jiangsu Key Laboratory for Food Quality and Safety, State Key Laboratory 
      Cultivation Base of Ministry of Science and Technology, Institute of Plant 
      Protection, Jiangsu Academy of Agricultural Sciences, Nanjing 226019, People's 
      Republic of China.
FAU - Laborda, Pedro
AU  - Laborda P
AUID- ORCID: 0000-0002-4251-4670
AD  - School of Life Sciences, Nantong University, Nantong 226019, People's Republic of 
      China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20201015
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Benzimidazoles)
RN  - 0 (Carbamates)
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Pesticide Residues)
RN  - H75J14AA89 (carbendazim)
SB  - IM
MH  - Animals
MH  - Benzimidazoles/*analysis
MH  - Carbamates/*analysis
MH  - Chromatography, Liquid/*methods
MH  - Food Contamination/*analysis
MH  - Fruit/chemistry
MH  - Fungicides, Industrial/*analysis
MH  - Humans
MH  - Meat/analysis
MH  - Pesticide Residues/*analysis
MH  - Vegetables/chemistry
OTO - NOTNLM
OT  - Carbendazim
OT  - chromatography
OT  - food contaminants
OT  - matrix effect
OT  - pesticide residues
EDAT- 2020/10/17 06:00
MHDA- 2021/03/23 06:00
CRDT- 2020/10/16 05:31
PHST- 2020/10/17 06:00 [pubmed]
PHST- 2021/03/23 06:00 [medline]
PHST- 2020/10/16 05:31 [entrez]
AID - 10.1021/acs.jafc.0c04225 [doi]
PST - ppublish
SO  - J Agric Food Chem. 2020 Oct 28;68(43):11880-11894. doi: 10.1021/acs.jafc.0c04225. 
      Epub 2020 Oct 15.