PMID- 33061187
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220417
IS  - 0973-7723 (Electronic)
IS  - 0970-9134 (Print)
IS  - 0970-9134 (Linking)
VI  - 36
IP  - Suppl 1
DP  - 2020 Jan
TI  - Long-term experience with valve-sparing root reimplantation surgery in tricuspid 
      aortic valve.
PG  - 71-80
LID - 10.1007/s12055-019-00842-x [doi]
AB  - OBJECTIVE: To analyze our long-term experience with valve-sparing reimplantation 
      technique in treating aortic root aneurysm, aortic regurgitation, and aortic 
      dissection in patients with tricuspid aortic valve. METHODS: Between March 1998 
      and October 2018, 303 consecutive patients underwent valve-sparing reimplantation 
      in our institution. The mean age of this cohort was 52.9 +/- 15 years. Time to 
      event analysis was performed with the Kaplan-Meier method. Risk of death, 
      reoperation, and aortic regurgitation (AR) recurrence were analyzed using the 
      cox-regression method. RESULTS: In-hospital mortality was 1% (n = 3) of which two 
      were admitted for acute aortic dissection. Median follow-up was 5.81 years 
      ([IQR]: 2.8-10 years). Thirty-nine patients (14.4%) died during follow-up. At 5 
      and 10 years, overall survival was 92 +/- 2%and 75 +/- 4.9%, respectively. Seventeen 
      patients required late aortic valve reoperation. Freedom from valve reoperation 
      was 95 +/- 2% and 90 +/- 3%. Freedom from AR > 2+ and AR > 1+ at 10 years was 91 +/- 4% 
      and 71.5 +/- 4.6%, respectively. Significant multivariate predictors of death 
      included age, New York Heart Association dyspnea class (NYHA), type A acute 
      dissection (TAAD), and preoperative left ventricular end-diastolic diameter 
      (LVEDD). Significant multivariate predictors of AR recurrence included indication 
      for surgery, previous cardiac surgery, and presence of preoperative AR. Freedom 
      from events like major bleeding, thromboembolic events, and infective 
      endocarditis at 10 years were 97%, 98%, and 96%, respectively. CONCLUSIONS: 
      Aortic valve-sparing with the reimplantation technique has been performed for 
      over two decades in our institution, and the results in patients with tricuspid 
      aortic valve (TAV) are excellent in terms of survival and freedom from 
      valve-related adverse outcomes including valve reoperation. These results 
      continue supporting the use of valve sparing root replacement using the 
      reimplantation technique (VSRR) in patients with aortic aneurysm, irrespective of 
      whether they have preoperative AR or not. VSRR is safe, durable, and 
      reproducible, but further follow-up, well into the second decade is still 
      necessary.
CI  - (c) Indian Association of Cardiovascular-Thoracic Surgeons 2019.
FAU - Tamer, Saadallah
AU  - Tamer S
AUID- ORCID: 0000-0001-8256-3656
AD  - Pole de Recherche Cardiovasculaire, Institut de Recherche Experimentale et 
      Clinique (IREC), Universite Catholique de Louvain and Division of Cardiothoracic 
      and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium. 
      GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
FAU - Mastrobuoni, Stefano
AU  - Mastrobuoni S
AD  - Pole de Recherche Cardiovasculaire, Institut de Recherche Experimentale et 
      Clinique (IREC), Universite Catholique de Louvain and Division of Cardiothoracic 
      and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium. 
      GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
FAU - Momeni, Mona
AU  - Momeni M
AD  - Division of Anesthesiologyy, Cliniques Universitaires Saint-Luc, Brussels, 
      Belgium. GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
FAU - Aphram, Gaby
AU  - Aphram G
AD  - Pole de Recherche Cardiovasculaire, Institut de Recherche Experimentale et 
      Clinique (IREC), Universite Catholique de Louvain and Division of Cardiothoracic 
      and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium. 
      GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
FAU - Navarra, Emiliano
AU  - Navarra E
AD  - Pole de Recherche Cardiovasculaire, Institut de Recherche Experimentale et 
      Clinique (IREC), Universite Catholique de Louvain and Division of Cardiothoracic 
      and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium. 
      GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
FAU - Poncelet, Alain
AU  - Poncelet A
AD  - Pole de Recherche Cardiovasculaire, Institut de Recherche Experimentale et 
      Clinique (IREC), Universite Catholique de Louvain and Division of Cardiothoracic 
      and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium. 
      GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
FAU - Noirhomme, Philippe
AU  - Noirhomme P
AD  - Pole de Recherche Cardiovasculaire, Institut de Recherche Experimentale et 
      Clinique (IREC), Universite Catholique de Louvain and Division of Cardiothoracic 
      and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium. 
      GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
FAU - Astarci, Parla
AU  - Astarci P
AD  - Pole de Recherche Cardiovasculaire, Institut de Recherche Experimentale et 
      Clinique (IREC), Universite Catholique de Louvain and Division of Cardiothoracic 
      and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium. 
      GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
FAU - El Khoury, Gebrine
AU  - El Khoury G
AD  - Pole de Recherche Cardiovasculaire, Institut de Recherche Experimentale et 
      Clinique (IREC), Universite Catholique de Louvain and Division of Cardiothoracic 
      and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium. 
      GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
FAU - de Kerchove, Laurent
AU  - de Kerchove L
AD  - Pole de Recherche Cardiovasculaire, Institut de Recherche Experimentale et 
      Clinique (IREC), Universite Catholique de Louvain and Division of Cardiothoracic 
      and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium. 
      GRID: grid.48769.34. ISNI: 0000 0004 0461 6320
LA  - eng
PT  - Journal Article
DEP - 20190809
PL  - India
TA  - Indian J Thorac Cardiovasc Surg
JT  - Indian journal of thoracic and cardiovascular surgery
JID - 8700105
PMC - PMC7525735
OTO - NOTNLM
OT  - Aortic valve repair
OT  - Aortic valve-sparing surgery
OT  - Tricuspid aortic valve
COIS- Conflict of interestnone declared for any of the authors.
EDAT- 2020/10/17 06:00
MHDA- 2020/10/17 06:01
PMCR- 2021/01/01
CRDT- 2020/10/16 05:50
PHST- 2019/03/19 00:00 [received]
PHST- 2019/05/26 00:00 [revised]
PHST- 2019/05/30 00:00 [accepted]
PHST- 2020/10/16 05:50 [entrez]
PHST- 2020/10/17 06:00 [pubmed]
PHST- 2020/10/17 06:01 [medline]
PHST- 2021/01/01 00:00 [pmc-release]
AID - 842 [pii]
AID - 10.1007/s12055-019-00842-x [doi]
PST - ppublish
SO  - Indian J Thorac Cardiovasc Surg. 2020 Jan;36(Suppl 1):71-80. doi: 
      10.1007/s12055-019-00842-x. Epub 2019 Aug 9.