PMID- 33065349 OWN - NLM STAT- MEDLINE DCOM- 20210603 LR - 20210603 IS - 1878-8769 (Electronic) IS - 1878-8750 (Linking) VI - 145 DP - 2021 Jan TI - Clinical Results and Complications of Endoscopic Lumbar Interbody Fusion for Lumbar Degenerative Disease: A Meta-Analysis. PG - 396-404 LID - S1878-8750(20)32225-7 [pii] LID - 10.1016/j.wneu.2020.10.033 [doi] AB - BACKGROUND: Although endoscopic transforaminal lumbar interbody fusion (TLIF) may combine the advantages of minimally invasive fusion and endoscopic spine surgery, little evidence exists on endoscopic TLIF. This meta-analysis investigated the clinical results of endoscopic TLIF. METHODS: We performed a systematic search of Web-based electronic databases to identify articles on endoscopic lumbar interbody fusion. Only studies of water-based endoscopic TLIF with pedicle screw fixation were included. We analyzed preoperative and postoperative scores for the Oswestry Disability Index (ODI) and visual analog scales (VASs) for back and leg pain to evaluate clinical efficacy. The minimal clinically important difference (MCID) of VAS and ODI was analyzed. We calculated differences in means and 95% confidence intervals and investigated indications for endoscopic TLIF, surgical approaches for endoscopic TLIF, the endoscopic systems that were used, and procedure-related complications. RESULTS: Thirteen articles were included in this meta-analysis. Uniportal and biportal endoscopic systems were used. Six articles used the posterolateral approach and 7 used the trans-Kambin approach. Preoperative ODI and VAS scores for leg and back pain significantly improved after endoscopic TLIF with percutaneous pedicle screw fixation (P = 0.00). The ODI significantly improved by twice as much as the MCID. The mean change in the VAS for back and leg pain showed significant improvements over the MCID. The perioperative complications were usually minor. CONCLUSIONS: The early clinical results of endoscopic TLIF with percutaneous pedicle screw fixation are favorable. However, long-term outcomes should be investigated and randomized controlled trials should be conducted. CI - Copyright (c) 2020. Published by Elsevier Inc. FAU - Heo, Dong Hwa AU - Heo DH AD - Department of Neurosurgery and Orthopedics, Endoscopic Spine Surgery Center, Seoul Bumin Hospital, Seoul, South Korea. FAU - Lee, Dong Chan AU - Lee DC AD - Department of Neurosurgery, The Leon Wiltse Memorial Hospital, Anyang, South Korea. Electronic address: surgicel@hanmail.net. FAU - Kim, Hyeun Sung AU - Kim HS AD - Department of Neurosurgery, Gangnam Nanoori Hospital, Seoul, South Korea. FAU - Park, Choon Keun AU - Park CK AD - Department of Neurosurgery, The Leon Wiltse Memorial Hospital, Anyang, South Korea. FAU - Chung, Hungtae AU - Chung H AD - Department of Neurosurgery and Orthopedics, Endoscopic Spine Surgery Center, Seoul Bumin Hospital, Seoul, South Korea. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review DEP - 20201013 PL - United States TA - World Neurosurg JT - World neurosurgery JID - 101528275 SB - IM MH - Endoscopy/*methods MH - Humans MH - Intervertebral Disc Degeneration/*surgery MH - Lumbar Vertebrae/surgery MH - Minimally Invasive Surgical Procedures/methods MH - Spinal Fusion/*methods OTO - NOTNLM OT - Endoscopy OT - Fusion OT - Lumbar OT - Lumbar degenerative disease OT - Minimally invasive surgery OT - Transforaminal EDAT- 2020/10/17 06:00 MHDA- 2021/06/04 06:00 CRDT- 2020/10/16 20:11 PHST- 2020/08/17 00:00 [received] PHST- 2020/10/04 00:00 [revised] PHST- 2020/10/05 00:00 [accepted] PHST- 2020/10/17 06:00 [pubmed] PHST- 2021/06/04 06:00 [medline] PHST- 2020/10/16 20:11 [entrez] AID - S1878-8750(20)32225-7 [pii] AID - 10.1016/j.wneu.2020.10.033 [doi] PST - ppublish SO - World Neurosurg. 2021 Jan;145:396-404. doi: 10.1016/j.wneu.2020.10.033. Epub 2020 Oct 13.