PMID- 33075765
OWN - NLM
STAT- MEDLINE
DCOM- 20220307
LR  - 20220307
IS  - 1741-2552 (Electronic)
IS  - 1741-2552 (Linking)
VI  - 18
IP  - 3
DP  - 2021 Mar 8
TI  - Modulating and restoring inter-muscular coordination in stroke patients using 
      two-dimensional myoelectric computer interface: a cross-sectional and 
      longitudinal study.
LID - 10.1088/1741-2552/abc29a [doi]
AB  - Objective.Traditional training focuses on improving the motor function level of 
      the limbs or joint levels, while inter-muscular coordination plays an important 
      role in fine motor control and is often overlooked. The purpose of this study was 
      to investigate the changes in inter-muscular coordination induced by the 
      myoelectric-controlled interface (MCI) and the therapeutic effects of MCI-based 
      inter-muscular coordination training on stroke patients.Approach. Eleven stroke 
      patients, twenty young subjects and thirteen age-matched subjects were recruited 
      to determine the dimensionality effect of MCI on inter-muscular coordination in 
      the evaluation test. In addition, a stroke patient participated in a 20-day 
      training session to test the therapeutic effects as a case study analysis in the 
      training test. In these two tests, all subjects performed tracking tasks by 
      flexing/extending their elbows according to the biofeedback from one-dimensional 
      and two-dimensional (2D) MCI. Meanwhile, the electromyography and functional near 
      infrared spectroscopy signals were recorded simultaneously to reflect the muscle 
      and cortical activations.Main results. In all groups, as the MCI dimensionality 
      increased, the antagonist activation decreased significantly, while the 
      involvement in prefrontal cortex and primary motor cortex increased 
      significantly. A significant reduction in muscle activation and an increase in 
      cortical activation were found in the stroke patient, which might be due to a 
      progressive normalization of patient after the training.Significance. These 
      findings suggested that 2D MCI could be an effective tool to directly modulate 
      inter-muscular coordination for stroke patients. Inter-muscular coordination 
      training may restore the ability to coordinate agonist-antagonist muscle of 
      stroke patient and this improvement may be accompanied by cortical 
      reorganization.
CI  - (c) 2021 IOP Publishing Ltd.
FAU - Jian, Chuyao
AU  - Jian C
AD  - Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong 
      Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou 
      510275, People's Republic of China.
FAU - Deng, Linchuan
AU  - Deng L
AD  - Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong 
      Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou 
      510275, People's Republic of China.
FAU - Liu, Huihua
AU  - Liu H
AD  - Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, People's 
      Republic of China.
FAU - Yan, Tiebin
AU  - Yan T
AD  - Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, People's 
      Republic of China.
FAU - Wang, Xianyun
AU  - Wang X
AD  - Guangdong Work Injury Rehabilitation Center, Guangzhou 510440, People's Republic 
      of China.
FAU - Song, Rong
AU  - Song R
AUID- ORCID: 0000-0003-3662-116X
AD  - Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong 
      Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou 
      510275, People's Republic of China.
AD  - Shenzhen Research Institute of Sun Yat-sen University, Shenzhen 518057, People's 
      Republic of China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210308
PL  - England
TA  - J Neural Eng
JT  - Journal of neural engineering
JID - 101217933
SB  - IM
MH  - Computers
MH  - Cross-Sectional Studies
MH  - Electromyography
MH  - Humans
MH  - Longitudinal Studies
MH  - Muscle, Skeletal
MH  - *Stroke
MH  - *Stroke Rehabilitation/methods
OTO - NOTNLM
OT  - EMG
OT  - cortical reorganization
OT  - fNIRS
OT  - inter-muscular coordination
OT  - stroke rehabilitation
OT  - upper limb
EDAT- 2020/10/20 06:00
MHDA- 2022/03/08 06:00
CRDT- 2020/10/19 20:17
PHST- 2020/07/26 00:00 [received]
PHST- 2020/10/19 00:00 [accepted]
PHST- 2020/10/20 06:00 [pubmed]
PHST- 2022/03/08 06:00 [medline]
PHST- 2020/10/19 20:17 [entrez]
AID - 10.1088/1741-2552/abc29a [doi]
PST - epublish
SO  - J Neural Eng. 2021 Mar 8;18(3). doi: 10.1088/1741-2552/abc29a.