PMID- 33076080
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20220531
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 221
DP  - 2021 Jan 1
TI  - Preparation of bovine serum albumin restricted access 
      octadecyl/phenyl-mixed-functionalized magnetic silica nanoparticles for magnetic 
      solid phase extraction of antidepressants in aquatic products followed by 
      UHPLC-MS/MS.
PG  - 121458
LID - S0039-9140(20)30749-9 [pii]
LID - 10.1016/j.talanta.2020.121458 [doi]
AB  - Pharmaceuticals are widespread in aquatic ecosystem, which may pose a potential 
      threat to fish and human. In the study, a robust and reliable magnetic 
      solid-phase extraction (MSPE) based on bovine serum albumin (BSA) restricted 
      access octadecyl/phenyl-mixed-functionalized magnetic silica nanoparticles 
      (BSA-C18/Ph-Fe(3)O(4)@SiO(2) NPs) as sorbent was developed for the extraction of 
      venlafaxine, paroxetine, fluoxetine, norfluoxetine, sertraline and 
      diphenhydramine from the muscle extracts of aquatic products followed by 
      ultra-high performance liquid chromatography-tandem mass spectrometry 
      (UHPLC-MS/MS) detection. The homemade sorbent showed appropriate compatibility in 
      aqueous solution and good performance in reducing matrix interference of 
      snakehead muscle tissue extracts with absolute matrix effect ranging in 
      95.4%-105.5%. The protocol was validated in analyte-free snakehead muscle with 
      favorable recoveries ranging in 91.6%-103.6% and relative standard deviations 
      (RSDs) less than 9.5%. Limits of detection (LODs) of the drugs were lower than 
      0.018 mug kg(-1). Short-term drug-exposure experiments at low and high doses were 
      conducted on snakeheads, and the measured contents of analytes were in the range 
      0.029-9.58 mug kg(-1) with appropriate recoveries (90.0%-114.0%). The approach was 
      extensively applied for the analysis of twelve species of market-sale aquatic 
      products (total 37 samples), and up to 1.868 and 0.521 mug kg(-1) of 
      diphenhydramine and venlafaxine were measured, respectively. The approach shows 
      remarkable potential in biological complex samples.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Li, Dan
AU  - Li D
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
FAU - Xiong, Xiang
AU  - Xiong X
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
FAU - Zhuang, Simin
AU  - Zhuang S
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
FAU - Du, Zhifeng
AU  - Du Z
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
FAU - Xiong, Chaomei
AU  - Xiong C
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China. Electronic 
      address: cmxiong2002@hust.edu.cn.
FAU - Jiang, Hongliang
AU  - Jiang H
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
LA  - eng
PT  - Journal Article
DEP - 20200730
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
RN  - 0 (Antidepressive Agents)
RN  - 0 (Magnetite Nanoparticles)
RN  - 27432CM55Q (Serum Albumin, Bovine)
RN  - 7631-86-9 (Silicon Dioxide)
SB  - IM
MH  - Animals
MH  - Antidepressive Agents/*analysis
MH  - Chromatography, High Pressure Liquid
MH  - Ecosystem
MH  - Food Contamination/*analysis
MH  - Limit of Detection
MH  - Magnetic Phenomena
MH  - *Magnetite Nanoparticles
MH  - Seafood/*analysis
MH  - Serum Albumin, Bovine
MH  - *Silicon Dioxide
MH  - Solid Phase Extraction
MH  - Tandem Mass Spectrometry
OTO - NOTNLM
OT  - Antidepressants
OT  - Aquatic products
OT  - Bovine serum albumin (BSA) restricted access 
      octadecyl/phenyl-mixed-functionalized magnetic silica nanoparticles 
      (BSA-C18/Ph-Fe(3)O(4)@SiO(2) NPs)
OT  - Magnetic solid-phase extraction (MSPE)
OT  - UHPLC-MS/MS
EDAT- 2020/10/21 06:00
MHDA- 2021/05/15 06:00
CRDT- 2020/10/20 01:01
PHST- 2020/04/22 00:00 [received]
PHST- 2020/07/19 00:00 [revised]
PHST- 2020/07/23 00:00 [accepted]
PHST- 2020/10/20 01:01 [entrez]
PHST- 2020/10/21 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
AID - S0039-9140(20)30749-9 [pii]
AID - 10.1016/j.talanta.2020.121458 [doi]
PST - ppublish
SO  - Talanta. 2021 Jan 1;221:121458. doi: 10.1016/j.talanta.2020.121458. Epub 2020 Jul 
      30.