PMID- 33076214
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201103
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 9
IP  - 10
DP  - 2020 Oct 15
TI  - Estimating Minimal Clinically Important Differences for Knee Range of Motion 
      after Stroke.
LID - 10.3390/jcm9103305 [doi]
LID - 3305
AB  - The importance of knee sagittal kinematic parameters, as a predictor of walking 
      performance in post-stroke gait has been emphasised by numerous researchers. 
      However, no studies so far were designed to determine the minimal clinically 
      important differences (MCID), i.e., the smallest difference in the relevant score 
      for the kinematic gait parameters, which are perceived as beneficial for patients 
      with stroke. Studies focusing on clinically important difference are useful 
      because they can identify the clinical relevance of changes in the scores. The 
      purpose of the study was to estimate the MCID for knee range of motion (ROM) in 
      the sagittal plane for the affected and unaffected side at a chronic stage 
      post-stroke. Fifty individuals were identified in a database of a rehabilitation 
      clinic. We estimated MCID values using: an anchor-based method, 
      distribution-based method, linear regression analysis and specification of the 
      receiver operating characteristic (ROC) curve. In the anchor-based study, the 
      mean change in knee flexion/extension ROM for the affected/unaffected side in the 
      MCID group amounted to 8.48 degrees /6.81 degrees  (the first MCID estimate). In the 
      distribution-based study, the standard error of measurement for the no-change 
      group was 1.86 degrees /5.63 degrees  (the second MCID estimate). Method 3 analyses showed 
      7.71 degrees /4.66 degrees  change in the ROM corresponding to 1.85-point change in the Barthel 
      Index. The best cut-off point, determined with ROC curve, was the value 
      corresponding to 3.9 degrees /3.8 degrees  of change in the knee sagittal ROM for the 
      affected/unaffected side (the fourth MCID estimate). We have determined that, in 
      chronic stroke, MCID estimates of knee sagittal ROM for the affected side amount 
      to 8.48 degrees  and for the unaffected side to 6.81 degrees . These findings will assist 
      clinicians and researchers in interpreting the significance of changes observed 
      in kinematic sagittal plane parameters of the knee. The data are part of the 
      following clinical trial: Australian New Zealand Clinical Trials Registry: 
      ACTRN12617000436370.
FAU - Guzik, Agnieszka
AU  - Guzik A
AUID- ORCID: 0000-0002-4582-4383
AD  - Department of Physiotherapy, Institute of Health Sciences, Medical College, 
      University of Rzeszow, 35-959 Rzeszow, Poland.
FAU - Druzbicki, Mariusz
AU  - Druzbicki M
AUID- ORCID: 0000-0003-4511-8419
AD  - Department of Physiotherapy, Institute of Health Sciences, Medical College, 
      University of Rzeszow, 35-959 Rzeszow, Poland.
FAU - Wolan-Nieroda, Andzelina
AU  - Wolan-Nieroda A
AD  - Department of Physiotherapy, Institute of Health Sciences, Medical College, 
      University of Rzeszow, 35-959 Rzeszow, Poland.
FAU - Turolla, Andrea
AU  - Turolla A
AUID- ORCID: 0000-0002-1609-8060
AD  - Laboratory of Kinematics and Robotics IRCCS San Camillo Hospital, 30126 Venice, 
      Italy.
FAU - Kiper, Pawel
AU  - Kiper P
AD  - Azienda ULSS 3 Serenissima Physical Medicine and Rehabilitation Unit, 30126 
      Venice, Italy.
LA  - eng
PT  - Journal Article
DEP - 20201015
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC7602397
OTO - NOTNLM
OT  - gait
OT  - hemiplegia
OT  - minimal clinically important difference
OT  - stroke
COIS- The authors declare no conflict of interest.
EDAT- 2020/10/21 06:00
MHDA- 2020/10/21 06:01
PMCR- 2020/10/15
CRDT- 2020/10/20 01:02
PHST- 2020/09/14 00:00 [received]
PHST- 2020/09/30 00:00 [revised]
PHST- 2020/10/11 00:00 [accepted]
PHST- 2020/10/20 01:02 [entrez]
PHST- 2020/10/21 06:00 [pubmed]
PHST- 2020/10/21 06:01 [medline]
PHST- 2020/10/15 00:00 [pmc-release]
AID - jcm9103305 [pii]
AID - jcm-09-03305 [pii]
AID - 10.3390/jcm9103305 [doi]
PST - epublish
SO  - J Clin Med. 2020 Oct 15;9(10):3305. doi: 10.3390/jcm9103305.