PMID- 33076900
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20231112
IS  - 1471-2474 (Electronic)
IS  - 1471-2474 (Linking)
VI  - 21
IP  - 1
DP  - 2020 Oct 19
TI  - Evaluation of the standard procedure for the treatment of periprosthetic joint 
      infections (PJI) in Germany - results of a survey within the EndoCert initiative.
PG  - 694
LID - 10.1186/s12891-020-03670-y [doi]
LID - 694
AB  - BACKGROUND: The periprosthetic joint infection (PJI) is a severe complication in 
      the field of arthroplasty. Despite the rising number of primary joint 
      replacements, no unified therapeutic standard has been established for the 
      treatment of PJI yet. METHODS: A survey on the principles of treatment of PJI in 
      Germany was conducted. A total of 515 EndoProthetikZentren (EPZ) were included, 
      resulting in a response rate of 100%. RESULTS: For early infections 97.6% of the 
      centers use prosthesis-preserving procedures (DAIR). A one-stage exchange was 
      implemented by less than 50% of the centers. If implemented, this treatment 
      entails a prior selection of patients for a successful treatment. The two-stage 
      exchange is performed in all centers, and most centers proceed with the 
      implantation of a cemented spacer between stages. 75% of the centers proceed with 
      a center-based concept for the treatment of PJI. CONCLUSION: The aim of a uniform 
      PJI standard at the centers has not yet been fully achieved. Further improvements 
      within the certification were initiated. The most relevant treatment options in 
      Germany are displayed. The two-stage revision with a cemented spacer is the most 
      widely implemented treatment. This exposition of principles could help for the 
      further development of standardized treatment guidelines and definitions.
FAU - Rimke, Christina
AU  - Rimke C
AD  - Orthopadische Klinik und Poliklinik, Universitatsmedizin Rostock, Doberaner 
      Strasse 142, 18059, Rostock, Germany.
FAU - Enz, Andreas
AU  - Enz A
AUID- ORCID: 0000-0002-9258-487X
AD  - Orthopadische Klinik und Poliklinik, Universitatsmedizin Rostock, Doberaner 
      Strasse 142, 18059, Rostock, Germany. andreas.enz@med.uni-rostock.de.
FAU - Bail, Hermann Josef
AU  - Bail HJ
AD  - Klinik fur Orthopadie und Unfallchirurgie, Klinikum Nurnberg Sud, 
      Universitatsklinik der Paracelsus Medizinischen Privatuniversitat Nurnberg, 
      Breslauer Strasse 201, 90471, Nuremberg, Germany.
FAU - Heppt, Peter
AU  - Heppt P
AD  - OCE Orthopadie Centrum Erlangen, Nagelsbachstrasse 49A, 91052, Erlangen, Germany.
FAU - Kladny, Bernd
AU  - Kladny B
AD  - M&I Fachklinik Herzogenaurach, In der Reuth 1, 91074, Herzogenaurach, Germany.
FAU - von Lewinski, Gabriela
AU  - von Lewinski G
AD  - Klinik fur Unfallchirurgie, Orthopadie und Plastische Chirurgie, 
      Universitatsmedizin Gottingen, Robert-Koch-Strasse 40, 37075, Goettingen, Germany.
FAU - Lohmann, Christoph H
AU  - Lohmann CH
AD  - Orthopadische Universitatsklinik, Otto-von-Guericke Universitat Magdeburg, 
      Leipziger Str. 44, 39120, Magdeburg, Germany.
FAU - Osmanski-Zenk, Katrin
AU  - Osmanski-Zenk K
AD  - Orthopadische Klinik und Poliklinik, Universitatsmedizin Rostock, Doberaner 
      Strasse 142, 18059, Rostock, Germany.
FAU - Haas, Holger
AU  - Haas H
AD  - Allgemeine Orthopadie, Unfallchirurgie und Sportmedizin, Gemeinschaftskrankenhaus 
      St Elisabeth St Petrus St Johannes gGmbH, Haus St. Petrus / Bonner Talweg 4-6, 
      53113, Bonn, Germany.
FAU - Mittelmeier, Wolfram
AU  - Mittelmeier W
AD  - Orthopadische Klinik und Poliklinik, Universitatsmedizin Rostock, Doberaner 
      Strasse 142, 18059, Rostock, Germany.
LA  - eng
PT  - Journal Article
DEP - 20201019
PL  - England
TA  - BMC Musculoskelet Disord
JT  - BMC musculoskeletal disorders
JID - 100968565
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Debridement
MH  - Germany/epidemiology
MH  - Humans
MH  - *Prosthesis-Related Infections/diagnosis/epidemiology/therapy
MH  - Reoperation
MH  - Retrospective Studies
PMC - PMC7574524
OTO - NOTNLM
OT  - Certification
OT  - Incident reporting
OT  - Periprosthetic joint infection
OT  - Revision arthroplasty
OT  - Surveys
OT  - Two-stage revision
COIS- H. J. Bail, P. Heppt, B. Kladny, G. v. Lewinski, C. H. Lohmann, H. Haas and W. 
      Mittelmeier are voluntary members of the certification commission board of the 
      EndoCert. K. Osmanski-Zenk is funded fulltime via a third party-funded project of 
      EndoCert, which is the fully owned subsidiary of the German Society for 
      Orthopaedics and Orthopaedic Surgery. Ch. Rimke and A. Enz declare that there is 
      no conflict of interest.
EDAT- 2020/10/21 06:00
MHDA- 2021/05/15 06:00
PMCR- 2020/10/19
CRDT- 2020/10/20 05:39
PHST- 2020/06/19 00:00 [received]
PHST- 2020/09/24 00:00 [accepted]
PHST- 2020/10/20 05:39 [entrez]
PHST- 2020/10/21 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
PHST- 2020/10/19 00:00 [pmc-release]
AID - 10.1186/s12891-020-03670-y [pii]
AID - 3670 [pii]
AID - 10.1186/s12891-020-03670-y [doi]
PST - epublish
SO  - BMC Musculoskelet Disord. 2020 Oct 19;21(1):694. doi: 10.1186/s12891-020-03670-y.