PMID- 33078020
OWN - NLM
STAT- MEDLINE
DCOM- 20211028
LR  - 20211028
IS  - 2038-2502 (Electronic)
IS  - 0035-6484 (Linking)
VI  - 55
IP  - 5
DP  - 2020 Sep-Oct
TI  - [Validation of the Italian version of the Koukopoulos Mixed Depression Rating 
      Scale (KMDRS) in an Italian sample of subjects with mood disorders].
PG  - 281-291
LID - 10.1708/3457.34460 [doi]
AB  - BACKGROUND: The construct of mixed depression (MxD), namely the simultaneous 
      presence of excitatory symptoms during a depressive episode, has gained increased 
      interest in the recent years. The Koukopoulos Mixed Depression Rating Scale 
      (KMDRS) has been recently validated for the diagnosis and assessment of MxD. The 
      aim of this study was to validate the Italian version of the KMDRS. METHODS: 
      Patients with a major depressive episode (MDE) (N=396, age, mean=44.73 years, 
      SD=15.93) were recruited at Lucio Bini Center, Rome, Italy. All participants were 
      administered the Italian version of the KMDRS, the Montgomery-Asberg Depression 
      Rating Scale (MADRS), the Young Mania Rating Scale (YMRS), the Clinical Global 
      Impressions (CGI), and the Global Assessment of Functioning (GAF). We calculated 
      predictive validity, and performed Receiver Operator Curve (ROC) analysis, 
      Cronbach's alpha, and inter-rater reliability. RESULTS: Predictive validity 
      (C-statistic= 0.80; IC 95%: 0.75, 0.85) and capacity [OR=1.25+/-.03 (SE); 95% CI: 
      1.18, 1.32; p<.001] were good, matching those of the original version, whereas 
      internal consistency (Cronbach's alpha = .70, IC 95%: 0.65, 0.75) and interrater 
      reliability (Cohen's kappa= 0.74) were adequate. CONCLUSIONS: The agreement of 
      results with those of the original version point to the validity of the Italian 
      version of KMDRS in assessing MxD.
FAU - Koukopoulos, Alexia Emilia
AU  - Koukopoulos AE
AD  - Centro Lucio Bini, Roma - Azienda Ospedaliera Universitaria Policlinico Umberto 
      I, Sapienza Universita di Roma.
FAU - Simonetti, Alessio
AU  - Simonetti A
AD  - Centro Lucio Bini, Roma - Menninger Department of Psychiatry and Behavioral 
      Sciences, Baylor College of Medicine, Houston, TX, USA - Dipartimento di 
      Neurologia e Psichiatria, Sapienza Universita di Roma.
FAU - Janiri, Delfina
AU  - Janiri D
AD  - Centro Lucio Bini, Roma - Dipartimento di Neurologia e Psichiatria, Sapienza 
      Universita di Roma.
FAU - De Chiara, Lavinia
AU  - De Chiara L
AD  - Centro Lucio Bini, Roma - Azienda Ospedaliera Universitaria Ospedale Sant'Andrea, 
      Dipartimento NESMOS, Sapienza Universita di Roma.
FAU - Kotzalidis, Georgios D
AU  - Kotzalidis GD
AD  - Centro Lucio Bini, Roma - Azienda Ospedaliera Universitaria Ospedale Sant'Andrea, 
      Dipartimento NESMOS, Sapienza Universita di Roma.
FAU - Sani, Gabriele
AU  - Sani G
LA  - ita
PT  - Journal Article
TT  - Validazione della versione italiana della Koukopoulos Mixed Depression Rating 
      Scale (KMDRS) in un campione di pazienti italiani affetti da disturbi dell'umore.
PL  - Italy
TA  - Riv Psichiatr
JT  - Rivista di psichiatria
JID - 0425672
SB  - IM
MH  - Adult
MH  - Depression
MH  - *Depressive Disorder, Major/diagnosis
MH  - Humans
MH  - Italy
MH  - Mood Disorders/diagnosis
MH  - Psychiatric Status Rating Scales
MH  - Psychometrics
MH  - Reproducibility of Results
EDAT- 2020/10/21 06:00
MHDA- 2021/10/29 06:00
CRDT- 2020/10/20 06:24
PHST- 2020/10/20 06:24 [entrez]
PHST- 2020/10/21 06:00 [pubmed]
PHST- 2021/10/29 06:00 [medline]
AID - 10.1708/3457.34460 [doi]
PST - ppublish
SO  - Riv Psichiatr. 2020 Sep-Oct;55(5):281-291. doi: 10.1708/3457.34460.