PMID- 33081476 OWN - NLM STAT- MEDLINE DCOM- 20210514 LR - 20210514 IS - 2224-5839 (Electronic) IS - 2224-5820 (Linking) VI - 10 IP - 2 DP - 2021 Feb TI - Efficacy of modified rubber band ligation in the treatment of grade III internal hemorrhoids. PG - 1191-1197 LID - 10.21037/apm-19-657 [doi] AB - BACKGROUND: Traditional rubber band ligation can improve the symptoms of hemorrhoids, the techniques used vary among centers and the degree of hemorrhoids may also affect the therapeutic efficacy and postoperative outcome, especially for patients with grade III hemorrhoids (hemorrhoid prolapses). This study aimed to investigate the clinical efficacy of modified rubber band ligation (MRBL) in the treatment of grade III internal hemorrhoids. METHODS: A total of 120 patients with grade III internal hemorrhoids were randomly assigned to receive MRBL or Milligan-Morgan haemorrhoidectomy (MMH) (n=60 per group). The post-operative pain, bleeding, urine retention and feeling of anal distension were recorded, and the resting anal pressure (RAP) and post-operative recurrence rate were compared between two groups. RESULTS: The post-operative pain, bleeding and urine retention in the MRBL group were improved significantly as compared with the MMH group (P<0.05), but the feeling of anal distension was similar between them (P>0.05). The RAP remained unchanged after MRBL, but the RAP at 1 month after surgery in the MMH group increased markedly (P<0.01) as compared with that before surgery and was significantly higher than that in the MRBL group (P<0.01). The post-operative recurrence rate was comparable between two groups (P>0.05). CONCLUSIONS: As compared with traditional MMH, MRBL is effective to attenuate the post-operative pain and other discomforts and stabilize the RA. Thus, MRBL is an ideal choice for the treatment of grade III internal hemorrhoids. FAU - Jin, Lei AU - Jin L AD - Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. FAU - Yang, Haojie AU - Yang H AD - Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. FAU - Qin, Kaijian AU - Qin K AD - Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. FAU - Li, Ying AU - Li Y AD - Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. FAU - Cui, Can AU - Cui C AD - Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. FAU - Wu, Renjie AU - Wu R AD - Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. FAU - Wang, Zhenyi AU - Wang Z AD - Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. drxinhuo@163.com. FAU - Wu, Jiong AU - Wu J AD - Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. tcmoctober9@163.com. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20201012 PL - China TA - Ann Palliat Med JT - Annals of palliative medicine JID - 101585484 SB - IM MH - *Digestive System Surgical Procedures MH - *Hemorrhoids/surgery MH - Humans MH - Ligation MH - Pain, Postoperative MH - Treatment Outcome OTO - NOTNLM OT - Milligan-Morgan haemorrhoidectomy OT - Rubber band ligation OT - grade III internal hemorrhoids OT - modified technique EDAT- 2020/10/22 06:00 MHDA- 2021/05/15 06:00 CRDT- 2020/10/21 05:36 PHST- 2019/12/24 00:00 [received] PHST- 2020/09/02 00:00 [accepted] PHST- 2020/10/22 06:00 [pubmed] PHST- 2021/05/15 06:00 [medline] PHST- 2020/10/21 05:36 [entrez] AID - apm-19-657 [pii] AID - 10.21037/apm-19-657 [doi] PST - ppublish SO - Ann Palliat Med. 2021 Feb;10(2):1191-1197. doi: 10.21037/apm-19-657. Epub 2020 Oct 12.