PMID- 3308456
OWN - NLM
STAT- MEDLINE
DCOM- 19871113
LR  - 20190828
IS  - 0301-5548 (Print)
IS  - 0301-5548 (Linking)
VI  - 56
IP  - 5
DP  - 1987
TI  - The effect of dietary carbohydrate intake on the metabolic response to prolonged 
      walking on consecutive days.
PG  - 583-91
AB  - Six healthy subjects walked 37 km per day for four consecutive days on two 
      occasions one month apart; on one walk, subjects consumed a high carbohydrate 
      (CHO) diet (85 +/- 1% CHO, Mean +/- SE) and on the other walk an isocaloric low 
      CHO diet (2 +/- 0% CHO) was consumed. Subjects were fasted each day until after 
      the completion of the walk. Blood samples were obtained at rest prior to exercise 
      and after completion of each of three laps of 12.3 km. Exercise intensity 
      corresponded to approximately 17% of VO2max. The first day of each walk 
      demonstrated that the pattern of substrate mobilisation in response to this type 
      of exercise is highly reproducible, there being no difference in any of the 
      parameters measured between the two walks. Circulating glucose, lactate, insulin 
      and triglyceride levels remained essentially unchanged; alanine fell 
      progressively and glycerol, free fatty acid (FFA) and 3-hydroxybutyrate (BHB) 
      rose progressively. After the first day there was a general tendency for the 
      blood glucose concentration to decline as exercise progressed; by the end of the 
      walk on Day 2, blood glucose was lower on the low CHO diet than on the high CHO 
      diet. On Day 4 plasma insulin was higher (p less than 0.05) on the high CHO diet 
      than on the low CHO diet and declined progressively on both diets. Blood lactate 
      and alanine concentrations were generally higher at rest on the high CHO diet, 
      but fell so that no differences existed by the end of exercise.(ABSTRACT 
      TRUNCATED AT 250 WORDS)
FAU - Maughan, R J
AU  - Maughan RJ
AD  - Department of Environmental and Occupational Medicine, University Medical School, 
      Aberdeen, Scotland.
FAU - Greenhaff, P L
AU  - Greenhaff PL
FAU - Gleeson, M
AU  - Gleeson M
FAU - Fenn, C E
AU  - Fenn CE
FAU - Leiper, J B
AU  - Leiper JB
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Eur J Appl Physiol Occup Physiol
JT  - European journal of applied physiology and occupational physiology
JID - 0410266
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Fatty Acids, Nonesterified)
RN  - 0 (Hydroxybutyrates)
RN  - 0 (Insulin)
RN  - 0 (Lactates)
RN  - 0 (Triglycerides)
RN  - OF5P57N2ZX (Alanine)
RN  - PDC6A3C0OX (Glycerol)
SB  - IM
MH  - Adult
MH  - Alanine/blood
MH  - Blood Glucose/metabolism
MH  - Dietary Carbohydrates/*pharmacology
MH  - Fatty Acids, Nonesterified/blood
MH  - Glycerol/blood
MH  - Humans
MH  - Hydroxybutyrates/blood
MH  - Insulin/blood
MH  - Lactates/blood
MH  - Male
MH  - *Physical Exertion
MH  - Time Factors
MH  - Triglycerides/blood
EDAT- 1987/01/01 00:00
MHDA- 1987/01/01 00:01
CRDT- 1987/01/01 00:00
PHST- 1987/01/01 00:00 [pubmed]
PHST- 1987/01/01 00:01 [medline]
PHST- 1987/01/01 00:00 [entrez]
AID - 10.1007/BF00635374 [doi]
PST - ppublish
SO  - Eur J Appl Physiol Occup Physiol. 1987;56(5):583-91. doi: 10.1007/BF00635374.