PMID- 33086950
OWN - NLM
STAT- MEDLINE
DCOM- 20210825
LR  - 20210825
IS  - 2472-5625 (Electronic)
IS  - 2472-5625 (Linking)
VI  - 4
IP  - 1
DP  - 2020 Jan
TI  - Autoimmune haemolytic anaemia caused by anti-M antibody in a patient with 
      Kawasaki disease.
PG  - 99-101
LID - 10.1080/24725625.2019.1681654 [doi]
AB  - Intravenous immunoglobulin (IVIG) is a standard therapy for Kawasaki disease 
      (KD), because it prevents formation of coronary artery aneurysm, a major 
      complication of KD. Herein, we report a 3-year-old boy with KD complicated by 
      haemolytic anaemia (HA) which developed following two courses of IVIG. Although 
      both direct and indirect antiglobulin tests and anti-M antibodies were positive 
      in his blood obtained after the onset of HA, indirect antiglobulin tests and 
      anti-M antibodies were negative either in the blood sample before the treatment 
      or the same lot of IVIG products as those used for the therapy, suggesting 
      autoimmune mechanism. This is, to our knowledge, the first report of autoimmune 
      HA caused by anti-M autoantibodies after IVIG therapy in KD.
FAU - Shimomura, Masaki
AU  - Shimomura M
AUID- ORCID: 0000-0002-6569-2381
AD  - Center for Pediatric Allergy and Rheumatology, KKR Sapporo Medical Center, 
      Sapporo, Japan.
FAU - Okura, Yuka
AU  - Okura Y
AUID- ORCID: 0000-0003-1050-2103
AD  - Center for Pediatric Allergy and Rheumatology, KKR Sapporo Medical Center, 
      Sapporo, Japan.
FAU - Ohta, Osamu
AU  - Ohta O
AD  - Center for Pediatric Allergy and Rheumatology, KKR Sapporo Medical Center, 
      Sapporo, Japan.
FAU - Takahashi, Yutaka
AU  - Takahashi Y
AD  - Center for Pediatric Allergy and Rheumatology, KKR Sapporo Medical Center, 
      Sapporo, Japan.
FAU - Kobayashi, Ichiro
AU  - Kobayashi I
AUID- ORCID: 0000-0003-4956-4010
AD  - Center for Pediatric Allergy and Rheumatology, KKR Sapporo Medical Center, 
      Sapporo, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20191105
PL  - England
TA  - Mod Rheumatol Case Rep
JT  - Modern rheumatology case reports
JID - 101761026
RN  - 0 (Autoantibodies)
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Anemia, Hemolytic, Autoimmune/diagnosis/*etiology/therapy
MH  - Autoantibodies/*immunology
MH  - Autoimmunity
MH  - Child, Preschool
MH  - Coombs Test
MH  - Humans
MH  - Immunoglobulins, Intravenous/administration & dosage
MH  - Male
MH  - Mucocutaneous Lymph Node Syndrome/*complications/*immunology
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Anti-M antibody
OT  - Kawasaki disease
OT  - haemolytic anaemia
OT  - intravenous immunoglobulin
EDAT- 2020/10/23 06:00
MHDA- 2021/08/26 06:00
CRDT- 2020/10/22 05:25
PHST- 2020/10/22 05:25 [entrez]
PHST- 2020/10/23 06:00 [pubmed]
PHST- 2021/08/26 06:00 [medline]
AID - 10.1080/24725625.2019.1681654 [doi]
PST - ppublish
SO  - Mod Rheumatol Case Rep. 2020 Jan;4(1):99-101. doi: 10.1080/24725625.2019.1681654. 
      Epub 2019 Nov 5.