PMID- 33087585
OWN - NLM
STAT- MEDLINE
DCOM- 20210823
LR  - 20210823
IS  - 1557-2501 (Electronic)
IS  - 1042-3931 (Linking)
VI  - 32
IP  - 12
DP  - 2020 Dec
TI  - Caval Valve Implantation for Tricuspid Regurgitation: Insights From the United 
      States Caval Valve Registry.
PG  - 470-475
LID - JIC20201022-2 [pii]
AB  - BACKGROUND: We sought to describe the outcomes of patients who underwent caval 
      valve implantation (CAVI) for treatment of severe tricuspid regurgitation (TR) in 
      the United States. Previous studies on CAVI have used a variety of techniques and 
      transcatheter valves. We present our findings from CAVI with inferior vena cava 
      (IVC) implant only using a single valve. METHODS: Patients who were determined to 
      be poor candidates for tricuspid valve surgery and underwent CAVI in the United 
      States from March 1, 2013 through March 1, 2018 were included in this study. Data 
      during hospitalizations and interim outpatient follow-up from each individual 
      site were collected and entered into a central password-protected database. 
      RESULTS: A total of 24 patients were treated. The median age was 79.5 years, 63% 
      were women, and 96% were white. Twenty-three of 24 patients underwent valve 
      implantation with a 29 mm Sapien 3 valve (Edwards Lifesciences). There was a 100% 
      rate of successful valve implantation. There were no cases requiring emergency 
      surgery. Thirty-day mortality rate was 25%. The median survival as of last 
      follow-up of all patients was 350 days. Pre- and postprocedure New York Heart 
      Association (NYHA) class data were available in 11 of 24 patients; of these 11 
      patients, 72.7% improved at least 1 NYHA class from baseline. CONCLUSION: CAVI 
      may be performed safely in a high surgical risk population with severe tricuspid 
      regurgitation. Dedicated studies with longer-term follow-up are needed.
FAU - O'Neill, Brian P
AU  - O'Neill BP
AD  - Henry Ford Hospital, Clara Ford Pavilion #440, 2799 W. Grand Blvd, Detroit, MI 
      48202 USA. boneil3@hfhs.org.
FAU - Negrotto, Sara
AU  - Negrotto S
FAU - Yu, Daohai
AU  - Yu D
FAU - Lakhter, Vladimir
AU  - Lakhter V
FAU - Depta, Jeremiah
AU  - Depta J
FAU - McCabe, James M
AU  - McCabe JM
FAU - Dube, Sandeep
AU  - Dube S
FAU - Vaikom, Mahadevan
AU  - Vaikom M
FAU - Wang, Dee Dee
AU  - Wang DD
FAU - Patil, Pravin
AU  - Patil P
FAU - Lindman, Brian
AU  - Lindman B
FAU - Iglessis-Azuaje, Ignacio
AU  - Iglessis-Azuaje I
FAU - Fredi, Joseph
AU  - Fredi J
FAU - Lu, Xiaoning
AU  - Lu X
FAU - O'Neill, William W
AU  - O'Neill WW
LA  - eng
PT  - Journal Article
DEP - 20201022
PL  - United States
TA  - J Invasive Cardiol
JT  - The Journal of invasive cardiology
JID - 8917477
SB  - IM
MH  - Aged
MH  - Cardiac Catheterization
MH  - Female
MH  - *Heart Valve Prosthesis
MH  - *Heart Valve Prosthesis Implantation
MH  - Humans
MH  - Male
MH  - Prosthesis Design
MH  - Registries
MH  - Severity of Illness Index
MH  - Treatment Outcome
MH  - Tricuspid Valve/diagnostic imaging/surgery
MH  - *Tricuspid Valve Insufficiency/diagnosis/epidemiology/surgery
MH  - United States/epidemiology
OTO - NOTNLM
OT  - caval valve implantation
OT  - transcatheter aortic valve
OT  - tricuspid regurgitation
OT  - tricuspid valve surgery
EDAT- 2020/10/23 06:00
MHDA- 2021/08/24 06:00
CRDT- 2020/10/22 05:29
PHST- 2020/10/23 06:00 [pubmed]
PHST- 2021/08/24 06:00 [medline]
PHST- 2020/10/22 05:29 [entrez]
AID - JIC20201022-2 [pii]
PST - ppublish
SO  - J Invasive Cardiol. 2020 Dec;32(12):470-475. Epub 2020 Oct 22.