PMID- 33087684
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201022
IS  - 1884-7110 (Electronic)
IS  - 0021-5287 (Linking)
VI  - 110
IP  - 4
DP  - 2019
TI  - [A CASE REPORT OF Xp11.2 TRANSLOCATION RENAL CELL CARTINOMA SUSPECTED RENAL 
      PELVIC CARCINOMA].
PG  - 234-238
LID - 10.5980/jpnjurol.110.234 [doi]
AB  - The patient was a 33-year-old female who visited the Department of 
      Gastroenterology of this hospital after experiencing lower abdominal pain and 
      nausea. The patient was referred to this department after suspicions of right 
      kidney hemorrhage revealed by non-contrast computed tomography (CT). We also 
      identified hematuria macroscopically, and contrast-enhanced CT scans revealed 
      uneven deep staining in the upper right kidney during the early phase. 
      Furthermore, by the late phase, we identified a 29-mm solid tumor with no 
      staining. There was no clear pseudomembrane and no clear boundary with the kidney 
      parenchyma. Additionally, there was no metastasis to the lymph nodes and other 
      organs. Based on the above findings, we suspected renal parenchymal infiltration 
      of right renal cell carcinoma (RCC) or right renal pelvic carcinoma. Since the 
      patient was young, we considered the risk of the residual tumor and performed 
      total nephroureterectomy and lymph node dissection with an enlarged view. The 
      inside of the resected tumor specimen showed significant necrosis and hematoma 
      spread, which had infiltrated the renal pelvis. Based on the characteristic 
      histological findings and genetic results obtained using the fluorescence in situ 
      hybridization (FISH) approach, we diagnosed the patient with Xp11.2 translocation 
      RCC. No additional treatments were provided after surgery, and even now the 
      patient is being followed-up through outpatient visits, but there has been no 
      recurrence or new metastasis. There have only been a few reported cases of Xp11.2 
      translocation RCC; therefore, in many cases, treatments and follow-up duration 
      according to the disease stage and disease prognosis have not been determined. In 
      this study, we report a case of Xp11.2 translocation RCC experienced at our 
      hospital, with additional literature considerations.
FAU - Hoshina, Hayato
AU  - Hoshina H
AD  - Department of Urology, NTT Medical Center Tokyo.
FAU - Nishikimi, Reo
AU  - Nishikimi R
AD  - Department of Urology, NTT Medical Center Tokyo.
FAU - Yoneoka, Yusuke
AU  - Yoneoka Y
AD  - Department of Urology, NTT Medical Center Tokyo.
FAU - Saikawa, Shu
AU  - Saikawa S
AD  - Department of Urology, NTT Medical Center Tokyo.
FAU - Inoue, Yasushi
AU  - Inoue Y
AD  - Department of Urology, NTT Medical Center Tokyo.
FAU - Abe, Mitsuhiro
AU  - Abe M
AD  - Department of Urology, NTT Medical Center Tokyo.
FAU - Yoshimatsu, Tadashi
AU  - Yoshimatsu T
AD  - Department of Urology, NTT Medical Center Tokyo.
FAU - Kameyama, Shuji
AU  - Kameyama S
AD  - Department of Urology, NTT Medical Center Tokyo.
FAU - Shiga, Yoshiyuki
AU  - Shiga Y
AD  - Department of Urology, NTT Medical Center Tokyo.
FAU - Masuda, Yoshio
AU  - Masuda Y
AD  - Department of Diagnostic Pathology, NTT Medical Center Tokyo.
FAU - Morikawa, Teppei
AU  - Morikawa T
AD  - Department of Diagnostic Pathology, NTT Medical Center Tokyo.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nihon Hinyokika Gakkai Zasshi
JT  - Nihon Hinyokika Gakkai zasshi. The japanese journal of urology
JID - 2984841R
SB  - IM
OTO - NOTNLM
OT  - TFE3
OT  - Xp11.2 translocation renal cell carcinoma
OT  - renal cell carcinoma
EDAT- 2019/01/01 00:00
MHDA- 2019/01/01 00:01
CRDT- 2020/10/22 05:29
PHST- 2020/10/22 05:29 [entrez]
PHST- 2019/01/01 00:00 [pubmed]
PHST- 2019/01/01 00:01 [medline]
AID - 10.5980/jpnjurol.110.234 [doi]
PST - ppublish
SO  - Nihon Hinyokika Gakkai Zasshi. 2019;110(4):234-238. doi: 
      10.5980/jpnjurol.110.234.