PMID- 33091580
OWN - NLM
STAT- MEDLINE
DCOM- 20210617
LR  - 20210617
IS  - 1096-1208 (Electronic)
IS  - 0882-4010 (Linking)
VI  - 149
DP  - 2020 Dec
TI  - The emergence of a novel recombinant porcine reproductive and respiratory 
      syndrome virus with an amino acid insertion in GP5 protein.
PG  - 104573
LID - S0882-4010(20)30939-6 [pii]
LID - 10.1016/j.micpath.2020.104573 [doi]
AB  - As an economic devastating virus, porcine reproductive and respiratory syndrome 
      virus (PRRSV) has spread globally, and seriously hinders the healthy development 
      of the swine industry worldwide. In recent years, however, recombinant PRRSV 
      strains are continuously emerging, resulting in the death of a large number of 
      pigs in China. In this study, we reported a NADC30-like PRRSV strain GD1909, a 
      recombinant virus, which may originate from NADC30-like and HUN4-like strains. 
      The GP5 protein of GD1909 strain has an asparagine insertion at position 60 and 
      has more complex glycosylation pattern. This should be helpful for a better 
      understanding of PRRSV molecular epidemiology and the prevention of PRRSV 
      infection in the future.
CI  - Copyright (c) 2020. Published by Elsevier Ltd.
FAU - Song, Zhongbao
AU  - Song Z
AD  - Key Laboratory of Fujian-Taiwan Animal Pathogen Biology, College of Animal 
      Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, 
      China. Electronic address: virus_szb@163.com.
FAU - Zhang, Qiaoya
AU  - Zhang Q
AD  - College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, 266109, 
      Shandong, China.
FAU - Chen, Ye
AU  - Chen Y
AD  - Key Laboratory of Fujian-Taiwan Animal Pathogen Biology, College of Animal 
      Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, 
      China.
FAU - Shen, Haiyang
AU  - Shen H
AD  - College of Animal Sciences and Technology, Zhongkai University of Agriculture and 
      Engineering, Guangzhou, Guangdong, 510225, China.
FAU - Yang, Guang
AU  - Yang G
AD  - College of Animal Sciences and Technology, Zhongkai University of Agriculture and 
      Engineering, Guangzhou, Guangdong, 510225, China.
FAU - Jiang, Ping
AU  - Jiang P
AD  - Key Laboratory of Animal Diseases Diagnostic and Immunology, Ministry of 
      Agriculture, MOE International Joint Collaborative Research Laboratory for Animal 
      Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural 
      University, Nanjing, Jiangsu, 210095, China.
FAU - Chen, Ji-Long
AU  - Chen JL
AD  - Key Laboratory of Fujian-Taiwan Animal Pathogen Biology, College of Animal 
      Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, 
      China.
FAU - Lin, Li
AU  - Lin L
AD  - College of Animal Sciences and Technology, Zhongkai University of Agriculture and 
      Engineering, Guangzhou, Guangdong, 510225, China. Electronic address: 
      linli@zhku.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20201019
PL  - England
TA  - Microb Pathog
JT  - Microbial pathogenesis
JID - 8606191
RN  - 0 (Amino Acids)
SB  - IM
MH  - Amino Acids
MH  - Animals
MH  - China
MH  - Genome, Viral
MH  - Phylogeny
MH  - *Porcine Reproductive and Respiratory Syndrome
MH  - *Porcine respiratory and reproductive syndrome virus/genetics
MH  - Swine
OTO - NOTNLM
OT  - GP5
OT  - Insertion
OT  - NADC30-Like
OT  - PRRSV
OT  - Recombination
EDAT- 2020/10/23 06:00
MHDA- 2021/06/22 06:00
CRDT- 2020/10/22 20:12
PHST- 2020/06/29 00:00 [received]
PHST- 2020/09/25 00:00 [revised]
PHST- 2020/10/09 00:00 [accepted]
PHST- 2020/10/23 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2020/10/22 20:12 [entrez]
AID - S0882-4010(20)30939-6 [pii]
AID - 10.1016/j.micpath.2020.104573 [doi]
PST - ppublish
SO  - Microb Pathog. 2020 Dec;149:104573. doi: 10.1016/j.micpath.2020.104573. Epub 2020 
      Oct 19.