PMID- 33094929
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221110
IS  - 2055-5822 (Electronic)
IS  - 2055-5822 (Linking)
VI  - 7
IP  - 6
DP  - 2020 Dec
TI  - Reduction in heart failure hospitalization rate during coronavirus disease 19 
      pandemic outbreak.
PG  - 4182-4188
LID - 10.1002/ehf2.13043 [doi]
AB  - AIMS: The recent coronavirus disease 19 (COVID-19) pandemic outbreak forced the 
      adoption of restraint measures, which modified the hospital admission patterns 
      for several diseases. The aim of the study is to investigate the rate of hospital 
      admissions for heart failure (HF) during the early days of the COVID-19 outbreak 
      in Italy, compared with a corresponding period during the previous year and an 
      earlier period during the same year. METHODS AND RESULTS: We performed a 
      retrospective analysis on HF admissions number at eight hospitals in Italy 
      throughout the study period (21 February to 31 March 2020), compared with an 
      inter-year period (21 February to 31 March 2019) and an intra-year period (1 
      January to 20 February 2020). The primary outcome was the overall rate of 
      hospital admissions for HF. A total of 505 HF patients were included in this 
      survey: 112 during the case period, 201 during intra-year period, and 192 during 
      inter-year period. The mean admission rate during the case period was 2.80 
      admissions per day, significantly lower compared with intra-year period (3.94 
      admissions per day; incidence rate ratio, 0.71; 95% confidence interval [CI], 
      0.56-0.89; P = 0.0037), or with inter-year (4.92 admissions per day; incidence 
      rate ratio, 0.57; 95% confidence interval, 0.45-0.72; P < 0.001). Patients 
      admitted during study period were less frequently admitted in New York Heart 
      Association (NYHA) Class II compared with inter-year period (P = 0.019). At 
      covariance analysis NYHA class was significantly lower in patients admitted 
      during inter-year control period, compared with patients admitted during case 
      period (P = 0.014). CONCLUSIONS: Admissions for HF were significantly reduced 
      during the lockdown due to the COVID-19 pandemic in Italy.
CI  - (c) 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on 
      behalf of the European Society of Cardiology.
FAU - Severino, Paolo
AU  - Severino P
AD  - Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, 
      Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
FAU - D'Amato, Andrea
AU  - D'Amato A
AD  - Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, 
      Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
FAU - Saglietto, Andrea
AU  - Saglietto A
AD  - Division of Cardiology, AOU Citta della Salute e della Scienza di Torino, Section 
      of Cardiology, Department of Medical Sciences, University of Turin, Turin, Italy.
FAU - D'Ascenzo, Fabrizio
AU  - D'Ascenzo F
AD  - Division of Cardiology, AOU Citta della Salute e della Scienza di Torino, Section 
      of Cardiology, Department of Medical Sciences, University of Turin, Turin, Italy.
FAU - Marini, Claudia
AU  - Marini C
AD  - Intensive Cardiac Care Unit and De Gasperis Cardio Center, ASST Grande Ospedale 
      Metropolitano Niguarda, Milan, Italy.
FAU - Schiavone, Marco
AU  - Schiavone M
AD  - Department of Cardiology, Luigi Sacco Hospital, Polo Universitario, Milan, Italy.
FAU - Ghionzoli, Nicolo
AU  - Ghionzoli N
AD  - Cardiovascular Diseases Unit, Le Scotte Hospital, University of Siena, Siena, 
      Italy.
FAU - Pirrotta, Filippo
AU  - Pirrotta F
AD  - Cardiovascular Diseases Unit, Le Scotte Hospital, University of Siena, Siena, 
      Italy.
FAU - Troiano, Francesca
AU  - Troiano F
AD  - Ivrea Hospital, Ivrea, Italy.
FAU - Cannillo, Margherita
AU  - Cannillo M
AD  - Ivrea Hospital, Ivrea, Italy.
FAU - Mennuni, Marco
AU  - Mennuni M
AD  - AOU Maggiore della Carita, Novara, Italy.
FAU - Rognoni, Andrea
AU  - Rognoni A
AD  - AOU Maggiore della Carita, Novara, Italy.
FAU - Rametta, Francesco
AU  - Rametta F
AD  - Sant'Andrea di Vercelli Hospital, Vercelli, Italy.
FAU - Galluzzo, Alessandro
AU  - Galluzzo A
AD  - Sant'Andrea di Vercelli Hospital, Vercelli, Italy.
FAU - Agnes, Gianluca
AU  - Agnes G
AD  - Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, 
      Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
FAU - Infusino, Fabio
AU  - Infusino F
AD  - Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, 
      Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
FAU - Pucci, Mariateresa
AU  - Pucci M
AD  - Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, 
      Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
AD  - Madre Giuseppina Vannini Hospital, Rome, Italy.
FAU - Lavalle, Carlo
AU  - Lavalle C
AD  - Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, 
      Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
FAU - Cacciotti, Luca
AU  - Cacciotti L
AD  - Madre Giuseppina Vannini Hospital, Rome, Italy.
FAU - Mather, Paul J
AU  - Mather PJ
AD  - Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, 
      PA, USA.
FAU - Grosso Marra, Walter
AU  - Grosso Marra W
AD  - Ivrea Hospital, Ivrea, Italy.
FAU - Ugo, Fabrizio
AU  - Ugo F
AD  - Sant'Andrea di Vercelli Hospital, Vercelli, Italy.
FAU - Forleo, Giovanni
AU  - Forleo G
AD  - Department of Cardiology, Luigi Sacco Hospital, Polo Universitario, Milan, Italy.
FAU - Viecca, Maurizio
AU  - Viecca M
AD  - Department of Cardiology, Luigi Sacco Hospital, Polo Universitario, Milan, Italy.
FAU - Morici, Nuccia
AU  - Morici N
AD  - Intensive Cardiac Care Unit and De Gasperis Cardio Center, ASST Grande Ospedale 
      Metropolitano Niguarda, Milan, Italy.
AD  - Department of Clinical Sciences and Community Health, University of Milan, Milan, 
      Italy.
FAU - Patti, Giuseppe
AU  - Patti G
AD  - AOU Maggiore della Carita, Novara, Italy.
AD  - Department of Translational Medicine, University of Eastern Piedmont, Novara, 
      Italy.
FAU - De Ferrari, Gaetano M
AU  - De Ferrari GM
AD  - Division of Cardiology, AOU Citta della Salute e della Scienza di Torino, Section 
      of Cardiology, Department of Medical Sciences, University of Turin, Turin, Italy.
FAU - Palazzuoli, Alberto
AU  - Palazzuoli A
AD  - Cardiovascular Diseases Unit, Le Scotte Hospital, University of Siena, Siena, 
      Italy.
FAU - Mancone, Massimo
AU  - Mancone M
AD  - Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, 
      Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
FAU - Fedele, Francesco
AU  - Fedele F
AD  - Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, 
      Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
LA  - eng
PT  - Journal Article
DEP - 20201023
PL  - England
TA  - ESC Heart Fail
JT  - ESC heart failure
JID - 101669191
SB  - IM
PMC - PMC7754919
OTO - NOTNLM
OT  - COVID-19
OT  - Heart failure
OT  - Hospitalization
OT  - Pandemic
COIS- None declared.
EDAT- 2020/10/24 06:00
MHDA- 2020/10/24 06:01
PMCR- 2020/10/23
CRDT- 2020/10/23 08:41
PHST- 2020/09/09 00:00 [revised]
PHST- 2020/05/29 00:00 [received]
PHST- 2020/09/16 00:00 [accepted]
PHST- 2020/10/24 06:00 [pubmed]
PHST- 2020/10/24 06:01 [medline]
PHST- 2020/10/23 08:41 [entrez]
PHST- 2020/10/23 00:00 [pmc-release]
AID - EHF213043 [pii]
AID - 10.1002/ehf2.13043 [doi]
PST - ppublish
SO  - ESC Heart Fail. 2020 Dec;7(6):4182-4188. doi: 10.1002/ehf2.13043. Epub 2020 Oct 
      23.