PMID- 33099041
OWN - NLM
STAT- MEDLINE
DCOM- 20210125
LR  - 20210125
IS  - 1873-0183 (Electronic)
IS  - 1568-9972 (Linking)
VI  - 19
IP  - 12
DP  - 2020 Dec
TI  - Minor salivary gland biopsy: Its role in the classification and prognosis of 
      Sjogren's syndrome.
PG  - 102690
LID - S1568-9972(20)30267-6 [pii]
LID - 10.1016/j.autrev.2020.102690 [doi]
AB  - Sjogren's syndrome (SS) is an autoimmune disorder characterized by mononuclear 
      cell infiltration in the exocrine glands, which leads to sicca syndrome 
      (xerostomia and xerophthalmia). The etiology of SS is unknown, but multiple 
      environmental factors (infectious, hormonal and stress-related), as well as 
      genetic factors, may play a role in its pathogenesis. The diagnosis of SS is 
      complex considering its clinical and paraclinical parameters may not be very 
      specific. The minor salivary gland biopsy (MSGB) has undoubtedly become crucial 
      for classifying and determining the prognosis of SS. The three main different 
      classification systems for its interpretation have been described by Chisholm and 
      Mason, Greenspan and Daniels, and Tarpley. However, this invasive procedure has 
      variable sensitivity and specificity as well as low reproducibility. The use of 
      additional methods, such as skin biopsy, imaging techniques, and serum/salivary 
      biomarkers, may be combined with current methods to develop a bioscore that could 
      increase diagnostic performance. In this review, we summarized the main 
      pathological findings in SS and the prognosis of patients with SS according to 
      the biopsy results.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Bautista-Vargas, Mario
AU  - Bautista-Vargas M
AD  - GIRAT: Grupo de Investigacion en Reumatologia, Autoinmunidad y Medicina 
      Traslacional, Fundacion Valle Del Lili and Universidad Icesi, Cali, Colombia.
FAU - Vivas, Alvaro J
AU  - Vivas AJ
AD  - GIRAT: Grupo de Investigacion en Reumatologia, Autoinmunidad y Medicina 
      Traslacional, Fundacion Valle Del Lili and Universidad Icesi, Cali, Colombia.
FAU - Tobon, Gabriel J
AU  - Tobon GJ
AD  - GIRAT: Grupo de Investigacion en Reumatologia, Autoinmunidad y Medicina 
      Traslacional, Fundacion Valle Del Lili and Universidad Icesi, Cali, Colombia. 
      Electronic address: gjtobon@icesi.edu.co.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20201022
PL  - Netherlands
TA  - Autoimmun Rev
JT  - Autoimmunity reviews
JID - 101128967
SB  - IM
MH  - Biopsy
MH  - Humans
MH  - Prognosis
MH  - Reproducibility of Results
MH  - *Salivary Glands, Minor/pathology
MH  - *Sjogren's Syndrome/diagnosis
OTO - NOTNLM
OT  - Chisholm and Mason
OT  - Focus score
OT  - Greenspan and Daniels
OT  - Minor salivary gland biopsy
OT  - Sjogren's syndrome
OT  - Tarpley
EDAT- 2020/10/26 06:00
MHDA- 2021/01/26 06:00
CRDT- 2020/10/25 00:02
PHST- 2020/05/19 00:00 [received]
PHST- 2020/05/25 00:00 [accepted]
PHST- 2020/10/26 06:00 [pubmed]
PHST- 2021/01/26 06:00 [medline]
PHST- 2020/10/25 00:02 [entrez]
AID - S1568-9972(20)30267-6 [pii]
AID - 10.1016/j.autrev.2020.102690 [doi]
PST - ppublish
SO  - Autoimmun Rev. 2020 Dec;19(12):102690. doi: 10.1016/j.autrev.2020.102690. Epub 
      2020 Oct 22.