PMID- 33102788
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231112
IS  - 2398-6352 (Electronic)
IS  - 2398-6352 (Linking)
VI  - 3
DP  - 2020
TI  - Neuromuscular block monitoring by smartphone application (i-TOF((c)) system): an 
      observational pilot study.
PG  - 137
LID - 10.1038/s41746-020-00344-w [doi]
LID - 137
AB  - Neuromuscular block monitoring is recommended by international guidelines to 
      improve myorelaxation during surgery and reduce the risk of postoperative 
      residual curarization. We conducted a pilot study to verify the efficacy of 
      i-TOF, a wireless neuromuscular monitoring device connectable to a smartphone, 
      comparing it with TOF WATCH SX. We enrolled 53 patients who underwent general 
      anesthesia. For each patient, we recorded by both devices, in different time 
      intervals, train-of-four (TOF) count/ratio after induction to general anesthesia 
      (TI0-TI3) and during recovery (TR0-TR3). Moreover, post-tetanic count (PTC) was 
      evaluated during deep neuromuscular block (TP0-TP2). We noticed no significant 
      differences between the devices in recorded mean values of TOF ratio, TOF count, 
      and PTC analyzed at time intervals for every phase of general anesthesia, 
      although the i-TOF tends to an underestimation compared to TOF WATCH SX. For each 
      patient, data sessions were successfully recorded by a smartphone. This aspect 
      could be relevant for clinicians in order to have a stored proof of good clinical 
      practice to be added on anesthesiologist records. By our results, i-TOF 
      demonstrates a comparable efficacy to TOF WATCH SX, suggesting that it could be a 
      proven alternative to standard devices for neuromuscular block monitoring. 
      Further studies are needed to confirm our findings.
CI  - (c) The Author(s) 2020.
FAU - Schiavoni, Lorenzo
AU  - Schiavoni L
AD  - Unit of Anaesthesia, Intensive Care and Pain Management, Department of Medicine, 
      Universita Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, 
      Italy. GRID: grid.9657.d. ISNI: 0000 0004 1757 5329
FAU - Pascarella, Giuseppe
AU  - Pascarella G
AD  - Unit of Anaesthesia, Intensive Care and Pain Management, Department of Medicine, 
      Universita Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, 
      Italy. GRID: grid.9657.d. ISNI: 0000 0004 1757 5329
FAU - Grande, Stefania
AU  - Grande S
AD  - Unit of Anaesthesia, Intensive Care and Pain Management, Department of Medicine, 
      Universita Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, 
      Italy. GRID: grid.9657.d. ISNI: 0000 0004 1757 5329
FAU - Agro, Felice Eugenio
AU  - Agro FE
AUID- ORCID: 0000-0001-8208-1120
AD  - Unit of Anaesthesia, Intensive Care and Pain Management, Department of Medicine, 
      Universita Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, 
      Italy. GRID: grid.9657.d. ISNI: 0000 0004 1757 5329
LA  - eng
PT  - Journal Article
DEP - 20201020
PL  - England
TA  - NPJ Digit Med
JT  - NPJ digital medicine
JID - 101731738
PMC - PMC7576770
OTO - NOTNLM
OT  - Information technology
OT  - Nerve conduction studies
COIS- Competing interestsThe authors declare no competing interests.
EDAT- 2020/10/27 06:00
MHDA- 2020/10/27 06:01
PMCR- 2020/10/20
CRDT- 2020/10/26 05:28
PHST- 2020/01/08 00:00 [received]
PHST- 2020/08/31 00:00 [accepted]
PHST- 2020/10/26 05:28 [entrez]
PHST- 2020/10/27 06:00 [pubmed]
PHST- 2020/10/27 06:01 [medline]
PHST- 2020/10/20 00:00 [pmc-release]
AID - 344 [pii]
AID - 10.1038/s41746-020-00344-w [doi]
PST - epublish
SO  - NPJ Digit Med. 2020 Oct 20;3:137. doi: 10.1038/s41746-020-00344-w. eCollection 
      2020.