PMID- 33104397
OWN - NLM
STAT- MEDLINE
DCOM- 20210114
LR  - 20210114
IS  - 1552-3365 (Electronic)
IS  - 0363-5465 (Linking)
VI  - 48
IP  - 14
DP  - 2020 Dec
TI  - Establishing the Minimal Clinically Important Difference, Patient Acceptable 
      Symptomatic State, and Substantial Clinical Benefit of the PROMIS Upper Extremity 
      Questionnaire After Rotator Cuff Repair.
PG  - 3439-3446
LID - 10.1177/0363546520964957 [doi]
AB  - BACKGROUND: The Patient-Reported Outcome Measurement Information System Upper 
      Extremity (PROMIS UE) questionnaire has been validated as an effective and 
      efficient outcome measure after rotator cuff repair (RCR). However, definitions 
      of clinically significant outcomes used in interpreting this outcome measure have 
      yet to be defined. PURPOSE: To define clinically significant outcomes of the 
      PROMIS UE questionnaire in patients undergoing arthroscopic RCR. STUDY DESIGN: 
      Cohort study (diagnosis); Level of evidence, 3. METHODS: We reviewed charts of 
      consecutive patients undergoing RCR in our institution between 2017 and 2018 and 
      included patients who were administered the PROMIS UE before surgery and 12 
      months after surgery. At 12 months postoperatively, patients were asked 
      domain-specific anchor questions regarding their function and satisfaction after 
      surgery, which were then used to determine the minimal clinically important 
      difference (MCID), Patient Acceptable Symptomatic State (PASS), and substantial 
      clinical benefit (SCB) using receiver operating characteristic and area under the 
      curve (AUC) analysis. Univariate and multivariate logistic regression analysis 
      was utilized to identify patient factors associated with clinically significant 
      outcomes. RESULTS: A total of 105 patients with RCR and minimum 12-month 
      postoperative PROMIS UE were included in the analysis. The defined clinically 
      significant outcomes were 4.87 for the MCID using a distribution-based method, 
      7.95 for the SCB (sensitivity, 0.708; specificity, 0.833; AUC, 0.760), and 39.00 
      for the PASS (sensitivity, 0.789; specificity, 0.720; AUC, 0.815). Among 
      respondents, 79.0%, 62.9%, and 64.8% achieved the MCID, SCB, and PASS score 
      thresholds, respectively. Workers' compensation was negatively associated with 
      achievement of the PASS. Lower preoperative PROMIS UE scores were associated with 
      obtaining the MCID (odds ratio [OR], 0.871; P = .001) and the SCB (OR, 0.900; P = 
      .040), whereas higher preoperative scores were predictive of achieving the PASS 
      (OR, 1.111; P = .020). CONCLUSION: This study defines the clinically significant 
      outcomes for the PROMIS UE after RCR, of which the majority of patients achieved 
      the MCID, PASS, and SCB at 12 months after surgery. These thresholds should be 
      considered in future study design and interpretation of PROMIS UE in patients 
      with RCR.
FAU - Haunschild, Eric D
AU  - Haunschild ED
AD  - Midwest Orthopaedics at Rush, Department of Orthopaedic Surgery, Rush University 
      Medical Center, Chicago, Illinois, USA.
FAU - Gilat, Ron
AU  - Gilat R
AD  - Midwest Orthopaedics at Rush, Department of Orthopaedic Surgery, Rush University 
      Medical Center, Chicago, Illinois, USA.
FAU - Fu, Michael C
AU  - Fu MC
AD  - Midwest Orthopaedics at Rush, Department of Orthopaedic Surgery, Rush University 
      Medical Center, Chicago, Illinois, USA.
FAU - Tauro, Tracy
AU  - Tauro T
AD  - Midwest Orthopaedics at Rush, Department of Orthopaedic Surgery, Rush University 
      Medical Center, Chicago, Illinois, USA.
FAU - Huddleston, Hailey P
AU  - Huddleston HP
AD  - Midwest Orthopaedics at Rush, Department of Orthopaedic Surgery, Rush University 
      Medical Center, Chicago, Illinois, USA.
FAU - Yanke, Adam B
AU  - Yanke AB
AD  - Midwest Orthopaedics at Rush, Department of Orthopaedic Surgery, Rush University 
      Medical Center, Chicago, Illinois, USA.
FAU - Forsythe, Brian
AU  - Forsythe B
AD  - Midwest Orthopaedics at Rush, Department of Orthopaedic Surgery, Rush University 
      Medical Center, Chicago, Illinois, USA.
FAU - Verma, Nikhil N
AU  - Verma NN
AD  - Midwest Orthopaedics at Rush, Department of Orthopaedic Surgery, Rush University 
      Medical Center, Chicago, Illinois, USA.
FAU - Cole, Brian J
AU  - Cole BJ
AD  - Midwest Orthopaedics at Rush, Department of Orthopaedic Surgery, Rush University 
      Medical Center, Chicago, Illinois, USA.
LA  - eng
PT  - Journal Article
DEP - 20201026
PL  - United States
TA  - Am J Sports Med
JT  - The American journal of sports medicine
JID - 7609541
SB  - IM
MH  - Arthroscopy
MH  - Cohort Studies
MH  - Humans
MH  - *Minimal Clinically Important Difference
MH  - *Patient Reported Outcome Measures
MH  - *Rotator Cuff/surgery
MH  - Rotator Cuff Injuries/*surgery
MH  - Treatment Outcome
MH  - Upper Extremity/surgery
OTO - NOTNLM
OT  - MCID, PASS
OT  - PROMIS
OT  - SCB
OT  - rotator cuff repair
EDAT- 2020/10/27 06:00
MHDA- 2021/01/15 06:00
CRDT- 2020/10/26 17:11
PHST- 2020/10/27 06:00 [pubmed]
PHST- 2021/01/15 06:00 [medline]
PHST- 2020/10/26 17:11 [entrez]
AID - 10.1177/0363546520964957 [doi]
PST - ppublish
SO  - Am J Sports Med. 2020 Dec;48(14):3439-3446. doi: 10.1177/0363546520964957. Epub 
      2020 Oct 26.