PMID- 33107450
OWN - NLM
STAT- MEDLINE
DCOM- 20201028
LR  - 20221207
IS  - 1998-3603 (Electronic)
IS  - 0970-9290 (Linking)
VI  - 31
IP  - 4
DP  - 2020 Jul-Aug
TI  - GCF and serum levels of omentin in periodontal health and disease of diabetic and 
      non-diabetic individuals: A comparative study.
PG  - 520-525
LID - 10.4103/ijdr.IJDR_796_18 [doi]
AB  - BACKGROUND: Omentin is an adipocytokine secreted by visceral adipose tissue cells 
      associated with the action of insulin-increasing, insulin-facilitated glucose 
      uptake. AIM: The aim of this study was to compare and evaluate the levels of 
      omentin in gingival crevicular fluid (GCF) and serum of periodontally healthy 
      individuals and chronic periodontitis (CP) patients with and without type 2 
      diabetes mellitus (T2DM). SETTINGS AND DESIGN: A hospital-based comparative study 
      was conducted amongst 40 subjects of age group 30-50 years. METHODS: Subjects 
      were divided into four groups, group I (10 healthy individuals), group II (10 
      T2DM), group III (10 CP only) and group IV (10 patients with CP and T2DM). 
      Clinical and systemic parameters assessed were gingival index (GI), plaque index 
      (PI), probing pocket depth (PPD), periodontal attachment level (PAL) and glycated 
      haemoglobin (HbA(1c)). Serum and GCF samples were collected and analysed for 
      omentin levels using the enzyme-linked immunosorbent assay (ELISA). RESULTS: 
      Although the mean GCF omentin levels were highest in group I and lowest in group 
      IV, it was not statistically significant. However, the serum omentin levels were 
      statistically significant, showing the highest mean level in group I and lowest 
      in group IV and serum levels were statistically significant. Also, the serum 
      omentin levels had a negative correlation with HbA(1c). CONCLUSION: The levels of 
      omentin reflect the diabetic status of an individual, which suggests that omentin 
      can be a potential anti-inflammatory marker and a therapeutic agent for 
      conditions like CP and T2DM.
FAU - Bagwe, Shreya
AU  - Bagwe S
AD  - Department of Periodontology, Dr. D.Y. Patil Dental College and Hospital, Dr. 
      D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.
FAU - Gopalakrishnan, D
AU  - Gopalakrishnan D
AD  - Department of Periodontology, Dr. D.Y. Patil Dental College and Hospital, Dr. 
      D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.
FAU - Mehta, Vini
AU  - Mehta V
AD  - Public Health Dentistry, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. 
      Patil Vidyapeeth, Pune, Maharashtra, India.
FAU - Mathur, Ankita
AU  - Mathur A
AD  - Department of Periodontology, Dr. D.Y. Patil Dental College and Hospital, Dr. 
      D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.
FAU - Kapare, Krutika
AU  - Kapare K
AD  - Department of Periodontology, Dr. D.Y. Patil Dental College and Hospital, Dr. 
      D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.
FAU - Deshpande, Apeksha
AU  - Deshpande A
AD  - Department of Periodontology, Dr. D.Y. Patil Dental College and Hospital, Dr. 
      D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.
LA  - eng
PT  - Journal Article
PL  - India
TA  - Indian J Dent Res
JT  - Indian journal of dental research : official publication of Indian Society for 
      Dental Research
JID - 9202990
RN  - 0 (Glycated Hemoglobin A)
MH  - *Chronic Periodontitis
MH  - *Diabetes Mellitus, Type 2
MH  - Gingival Crevicular Fluid/chemistry
MH  - Glycated Hemoglobin/analysis
MH  - Humans
MH  - Periodontal Index
OTO - NOTNLM
OT  - Diabetes
OT  - GCF
OT  - periodontitis
OT  - serum
COIS- None
EDAT- 2020/10/28 06:00
MHDA- 2020/10/29 06:00
CRDT- 2020/10/27 08:41
PHST- 2020/10/27 08:41 [entrez]
PHST- 2020/10/28 06:00 [pubmed]
PHST- 2020/10/29 06:00 [medline]
AID - IndianJDentRes_2020_31_4_520_298420 [pii]
AID - 10.4103/ijdr.IJDR_796_18 [doi]
PST - ppublish
SO  - Indian J Dent Res. 2020 Jul-Aug;31(4):520-525. doi: 10.4103/ijdr.IJDR_796_18.