PMID- 33108254
OWN - NLM
STAT- MEDLINE
DCOM- 20211124
LR  - 20220428
IS  - 0001-5458 (Print)
IS  - 0001-5458 (Linking)
VI  - 121
IP  - 6
DP  - 2021 Dec
TI  - LIFT: a feasible option for primary and recurrent fistulas.
PG  - 420-426
LID - 10.1080/00015458.2020.1841488 [doi]
AB  - BACKGROUND: The development of a surgical solution for anal fistulas with minimal 
      recurrence and morbidity remains a challenge. Ligation of the intersphincteric 
      fistula tract (LIFT), however, is a sphincter sparing technique that provides 
      complete resolution of the transsphincteric fistula as well as minimizing 
      recurrence and fecal incontinence. Our goal is to evaluate the efficacy of 
      fistula tract ligation for primary and recurrent fistulas. METHODS: A 
      retrospective single-center case study was conducted from data between 2015 and 
      2019 in a large district hospital in Antwerp, Belgium. Patients who underwent 
      LIFT were included. Demographic patient data as well as primary outcome during 
      the follow-up period were collected. A systematic literature review and analysis 
      was conducted with terms [ANAL FISTULA] [TREATMENT] [LIFT] [LIGATION OF 
      INTERSPHINCTERIC FISTULA]. Primary healing and recurrence associated with 
      surgical modifications were investigated. RESULTS: 4 out of 25 patients presented 
      with early failure (84% primary success rate) after a median follow-up period of 
      7 months. The median time until recurrence was 105 days. The success rate after a 
      redo ligation was 100%. Twenty-eight studies were included for review and divided 
      into three groups depending on the technical variation of the used technique. The 
      success rate was 74.2% for the LIFT group, 72.9% in the LIFT + group, and 77.5% 
      in the mLIFT group p = .92. CONCLUSION: LIFT is a feasible treatment option for 
      primary and recurrent fistulas, with excellent success rates where fistula 
      characteristics rather than chosen technique dictate the surgical outcome.
FAU - Van Hoof, Sander
AU  - Van Hoof S
AUID- ORCID: 0000-0001-8258-2822
AD  - GZA Sint Augustinus, Antwerpen, Belgium.
FAU - Van Dessel, Els
AU  - Van Dessel E
AUID- ORCID: 0000-0003-0958-0868
AD  - GZA Sint Augustinus, Antwerpen, Belgium.
FAU - Cools, Peter
AU  - Cools P
AUID- ORCID: 0000-0001-7108-4190
AD  - GZA Sint Augustinus, Antwerpen, Belgium.
LA  - eng
PT  - Journal Article
PT  - Systematic Review
DEP - 20201106
PL  - England
TA  - Acta Chir Belg
JT  - Acta chirurgica Belgica
JID - 0370571
SB  - IM
MH  - *Anal Canal
MH  - Humans
MH  - Organ Sparing Treatments
MH  - *Rectal Fistula/surgery
MH  - Recurrence
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Anal fistula
OT  - anorectal disease surgical treatment
OT  - ligation of intersphincteric fistula tract
EDAT- 2020/10/28 06:00
MHDA- 2021/11/25 06:00
CRDT- 2020/10/27 17:19
PHST- 2020/10/28 06:00 [pubmed]
PHST- 2021/11/25 06:00 [medline]
PHST- 2020/10/27 17:19 [entrez]
AID - 10.1080/00015458.2020.1841488 [pii]
AID - 10.1080/00015458.2020.1841488 [doi]
PST - ppublish
SO  - Acta Chir Belg. 2021 Dec;121(6):420-426. doi: 10.1080/00015458.2020.1841488. Epub 
      2020 Nov 6.