PMID- 33132938 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240329 IS - 1664-0640 (Print) IS - 1664-0640 (Electronic) IS - 1664-0640 (Linking) VI - 11 DP - 2020 TI - Adverse Events in Italian Nursing Homes During the COVID-19 Epidemic: A National Survey. PG - 578465 LID - 10.3389/fpsyt.2020.578465 [doi] LID - 578465 AB - Older people living in nursing homes (NHs) are particularly vulnerable in the ongoing COVID-19 pandemic, due to the high prevalence of chronic diseases and disabilities (e.g., dementia). The phenomenon of adverse events (AEs), intended as any harm or injury resulting from medical care or to the failure to provide care, has not yet been investigated in NHs during the pandemic. We performed a national survey on 3,292 NHs, either public or providing services both privately and within the national health system, out of the 3,417 NHs covering the whole Italian territory. An online questionnaire was addressed to the directors of each facility between March 24 and April 27, 2020. The list of NHs was provided by the Dementia Observatory, an online map of Italian services for people with dementia, which was one of the objectives of the implementation of the Italian National Dementia Plan. About 26% of residents in the Italian NHs for older people listed within the Dementia Observatory site had dementia. The objective of our study was to report the frequency of AEs that occurred during the months when SARS-CoV-2 spreading rate was at its highest in the Italian NHs and to identify which conditions and attributes were most associated with the occurrence of AEs by means of multivariate regression logistic analysis. Data are referred to 1,356 NHs that participated in the survey. The overall response rate was 41.2% over a time-period of six weeks (from March 24 to May 5). About one third of the facilities (444 out of 1,334) (33.3%) reported at least 1 adverse event, with a total of 2,000 events. Among the included NHs, having a bed capacity higher than the median of 60 beds (OR=1.57, CI95% 1.17-2.09; p=0.002), an observed increased in the use of psychiatric drugs (OR=1.80, CI95% 1.05-3.07; p=0.032), adopting physical restraint measures (OR=1.97, CI95% 1.47-2.64; p<0.001), residents hospitalized due to flu-like symptoms (OR =1.73, CI95% 1.28-2.32; p<0.001), and being located in specific geographic areas (OR=3.59, CI95% 1.81-7.08; OR = 2.90, CI95% 1.45-5.81 and OR = 4.02, CI05% 2.01-8.04 for, respectively, North-West, North-East and Centre vs South, p<0.001) were all factors positively associated to the occurrence of adverse events in the facility. Future recommendations for the management and care of residents in NHs during the COVID-19 pandemic should include specific statements for the most vulnerable populations, such as people with dementia. CI - Copyright (c) 2020 Lombardo, Salvi, Lacorte, Piscopo, Mayer, Ancidoni, Remoli, Bellomo, Losito, D'Ancona, Canevelli, Onder, Vanacore and The Italian National Institute of Health Nursing Home Study Group. FAU - Lombardo, Flavia L AU - Lombardo FL AD - National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy. FAU - Salvi, Emanuela AU - Salvi E AD - National Center for Drug Research and Evaluation, Italian National Institute of Health, Rome, Italy. FAU - Lacorte, Eleonora AU - Lacorte E AD - National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy. FAU - Piscopo, Paola AU - Piscopo P AD - Department of Neuroscience, Italian National Institute of Health, Rome, Italy. FAU - Mayer, Flavia AU - Mayer F AD - National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy. FAU - Ancidoni, Antonio AU - Ancidoni A AD - National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy. FAU - Remoli, Giulia AU - Remoli G AD - Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy. FAU - Bellomo, Guido AU - Bellomo G AD - National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy. FAU - Losito, Gilda AU - Losito G AD - Unit of Health Care and Deprivation of Liberty, Rome, Italy. FAU - D'Ancona, Fortunato AU - D'Ancona F AD - Department of Infectious Diseases, Italian National Institute of Health, Rome, Italy. FAU - Canevelli, Marco AU - Canevelli M AD - National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy. AD - Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy. FAU - Onder, Graziano AU - Onder G AD - Department of Cardiovascular, Endocrine-metabolic Diseases and Aging, Italian National Institute of Health, Rome, Italy. FAU - Vanacore, Nicola AU - Vanacore N AD - National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy. CN - Italian National Institute of Health Nursing Home Study Group LA - eng PT - Journal Article DEP - 20200930 PL - Switzerland TA - Front Psychiatry JT - Frontiers in psychiatry JID - 101545006 PMC - PMC7561357 OTO - NOTNLM OT - COVID-19 OT - Long-Term Care Facilities OT - adverse events OT - dementia OT - nursing homes OT - public health FIR - Ancidoni, Antonio IR - Ancidoni A FIR - Bacigalupo, Ilaria IR - Bacigalupo I FIR - Bellomo, Guido IR - Bellomo G FIR - Bertinato, Luigi IR - Bertinato L FIR - Canevelli, Marco IR - Canevelli M FIR - Carbonari, Patrizia IR - Carbonari P FIR - Carella, Maria Grazia IR - Carella MG FIR - Confaloni, Annamaria IR - Confaloni A FIR - Crestini, Alessio IR - Crestini A FIR - D'Ancona, Fortunato IR - D'Ancona F FIR - Faralli, Carla IR - Faralli C FIR - Fiaccavento, Simone IR - Fiaccavento S FIR - Francisci, Silvia IR - Francisci S FIR - Lombardo, Flavia L IR - Lombardo FL FIR - Lacorte, Eleonora IR - Lacorte E FIR - Lo Noce, Cinzia IR - Lo Noce C FIR - Luzi, Paola IR - Luzi P FIR - Lopez, Tania IR - Lopez T FIR - Mayer, Flavia IR - Mayer F FIR - Masocco, Maria IR - Masocco M FIR - Mazzola, Monica IR - Mazzola M FIR - Onder, Graziano IR - Onder G FIR - Palazzesi, Ilaria IR - Palazzesi I FIR - Penna, Luana IR - Penna L FIR - Pierannunzio, Daniela IR - Pierannunzio D FIR - Piscopo, Paola IR - Piscopo P FIR - Porrello, Maria Cristina IR - Porrello MC FIR - Remoli, Giulia IR - Remoli G FIR - Salvi, Emanuela IR - Salvi E FIR - Scaravelli, Giulia IR - Scaravelli G FIR - Siddu, Andrea IR - Siddu A FIR - Sipone, Sabrina IR - Sipone S FIR - Speziale, Lucia IR - Speziale L FIR - Tavilla, Andrea IR - Tavilla A FIR - Vanacore, Nicola IR - Vanacore N FIR - Palma, Mauro IR - Palma M FIR - Losito, Gilda IR - Losito G FIR - Pucciarelli, Gianluca IR - Pucciarelli G FIR - Accorgi, Daniela IR - Accorgi D FIR - Bedosti, Catia IR - Bedosti C FIR - Carraro, Gabriella IR - Carraro G FIR - Mongardi, Maria IR - Mongardi M FIR - Ferrari, Gianluca IR - Ferrari G EDAT- 2020/11/03 06:00 MHDA- 2020/11/03 06:01 PMCR- 2020/09/30 CRDT- 2020/11/02 06:14 PHST- 2020/06/30 00:00 [received] PHST- 2020/08/25 00:00 [accepted] PHST- 2020/11/02 06:14 [entrez] PHST- 2020/11/03 06:00 [pubmed] PHST- 2020/11/03 06:01 [medline] PHST- 2020/09/30 00:00 [pmc-release] AID - 10.3389/fpsyt.2020.578465 [doi] PST - epublish SO - Front Psychiatry. 2020 Sep 30;11:578465. doi: 10.3389/fpsyt.2020.578465. eCollection 2020.