PMID- 33133245
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240330
IS  - 1759-720X (Print)
IS  - 1759-7218 (Electronic)
IS  - 1759-720X (Linking)
VI  - 12
DP  - 2020
TI  - Choosing the right treatment for patients with psoriatic arthritis.
PG  - 1759720X20962623
LID - 10.1177/1759720X20962623 [doi]
LID - 1759720X20962623
AB  - Psoriatic arthritis (PsA) is a chronic inflammatory condition with articular and 
      extra-articular manifestations: peripheral arthritis, axial disease, enthesitis, 
      dactylitis, psoriasis, inflammatory bowel disease and uveitis. Anti-tumour 
      necrosis factors (anti-TNFs) have demonstrated clinical efficacies exceeding 
      those of conventional disease-modifying antirheumatic drugs (DMARDs). New 
      understanding in pathogenic pathways have led to novel therapeutic targets. The 
      current treatment paradigms emphasize early diagnosis and treatment, and treating 
      towards remission and low disease activity status, particularly in long-standing 
      disease. This review addresses the evidence of current treatment options for each 
      of the domains of PsA. We present a simple guide that weighs on clinical 
      efficacies for each PsA domain to aid clinicians in choosing the most appropriate 
      treatment for patients. We highlight the unmet need for biomarkers of treatment 
      response, and future perspectives with precision medicine in PsA.
CI  - (c) The Author(s), 2020.
FAU - Noviani, Maria
AU  - Noviani M
AD  - Department of Rheumatology and Immunology, Singapore General Hospital, Singapore.
FAU - Feletar, Marie
AU  - Feletar M
AD  - Rheumatologist, Melbourne, Victoria, Australia.
FAU - Nash, Peter
AU  - Nash P
AD  - School of Medicine, Griffith University, Brisbane, Queensland, Australia.
FAU - Leung, Ying Ying
AU  - Leung YY
AUID- ORCID: 0000-0001-8492-6342
AD  - Department of Rheumatology and Immunology, Singapore General Hospital, level 4, 
      Academia, 20 College Road, Outram Road, Singapore 169608, Singapore Duke-NUS 
      Medical School, Singapore.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20201013
PL  - England
TA  - Ther Adv Musculoskelet Dis
JT  - Therapeutic advances in musculoskeletal disease
JID - 101517322
PMC - PMC7576918
OTO - NOTNLM
OT  - manifestations
OT  - psoriatic arthritis
OT  - review
OT  - therapies
COIS- Conflict of interest statement: The authors declare that there is no conflict of 
      interest.
EDAT- 2020/11/03 06:00
MHDA- 2020/11/03 06:01
PMCR- 2020/10/13
CRDT- 2020/11/02 06:16
PHST- 2020/07/06 00:00 [received]
PHST- 2020/09/02 00:00 [accepted]
PHST- 2020/11/02 06:16 [entrez]
PHST- 2020/11/03 06:00 [pubmed]
PHST- 2020/11/03 06:01 [medline]
PHST- 2020/10/13 00:00 [pmc-release]
AID - 10.1177_1759720X20962623 [pii]
AID - 10.1177/1759720X20962623 [doi]
PST - epublish
SO  - Ther Adv Musculoskelet Dis. 2020 Oct 13;12:1759720X20962623. doi: 
      10.1177/1759720X20962623. eCollection 2020.