PMID- 33135583
OWN - NLM
STAT- MEDLINE
DCOM- 20210607
LR  - 20210607
IS  - 1466-447X (Electronic)
IS  - 0264-0414 (Linking)
VI  - 39
IP  - 5
DP  - 2021 Mar
TI  - Serum sclerostin and cytokine responses to prolonged sculling exercise in 
      highly-trained male rowers.
PG  - 591-597
LID - 10.1080/02640414.2020.1837428 [doi]
AB  - This study examined sclerostin and cytokine responses to an endurance training 
      session in male single sculling rowers. Sixteen highly trained rowers performed a 
      2-h rowing exercise (distance: 23.8 +/- 0.9 km; heart rate: 138 +/- 8  beats.min(-1); 
      intensity: 79.8 +/- 2.1% of the anaerobic threshold). Rowing resulted significant 
      increment (p < 0.05) in sclerostin (36%), interleukin (IL)-6 (345%), IL-10 (129%) 
      and monocyte chemoattractant protein-1 (MCP-1) (132%), while increases in irisin 
      (6%) and tumour necrosis factor-alpha (3%) were not significant (p > 0.05). There was 
      a correlation between the pre-to-post-exercise increase in sclerostin and the 
      distance covered (r = 0.67; p = 0.005) as a marker of energy expenditure, and 
      weekly training volume (r = 0.66; p = 0.005) as a marker of training stress. 
      Post-exercise gain in MCP-1 was the most important predictor of post-exercise 
      gain in sclerostin (beta = 0.543; p = 0.040). In conclusion, acute non-impact rowing 
      training session with a total body mode induced increases in sclerostin and also 
      in IL-6, IL-10 and MCP-1 concentrations, while post-exercise gain in MCP-1 was 
      the main determinant of post-exercise gain in sclerostin. Exercise-induced 
      increase in sclerostin could be regarded as a signal for metabolic reaction to 
      the energy cost of acute exercise in rowers.
FAU - Jurimae, Jaak
AU  - Jurimae J
AD  - Institute of Sport Sciences and Physiotherapy, Faculty of Medicine, University of 
      Tartu, Tartu, Estonia.
FAU - Purge, Priit
AU  - Purge P
AD  - Institute of Sport Sciences and Physiotherapy, Faculty of Medicine, University of 
      Tartu, Tartu, Estonia.
FAU - Tillmann, Vallo
AU  - Tillmann V
AD  - Institute of Clinical Medicine, Faculty of Medicine, University of Tartu, Tartu, 
      Estonia.
LA  - eng
PT  - Journal Article
DEP - 20201101
PL  - England
TA  - J Sports Sci
JT  - Journal of sports sciences
JID - 8405364
RN  - 0 (Adaptor Proteins, Signal Transducing)
RN  - 0 (Biomarkers)
RN  - 0 (Cytokines)
RN  - 0 (SOST protein, human)
SB  - IM
MH  - Adaptor Proteins, Signal Transducing/*blood
MH  - Adolescent
MH  - Adult
MH  - Biomarkers/blood
MH  - Cytokines/*blood
MH  - Exercise/*physiology
MH  - Humans
MH  - Male
MH  - Physical Endurance/*physiology
MH  - Water Sports/*physiology
MH  - Young Adult
OTO - NOTNLM
OT  - Blood biomarkers
OT  - athletes
OT  - endurance exercise
OT  - energy cost
OT  - non-impact
OT  - osteocyte
EDAT- 2020/11/03 06:00
MHDA- 2021/06/08 06:00
CRDT- 2020/11/02 08:41
PHST- 2020/11/03 06:00 [pubmed]
PHST- 2021/06/08 06:00 [medline]
PHST- 2020/11/02 08:41 [entrez]
AID - 10.1080/02640414.2020.1837428 [doi]
PST - ppublish
SO  - J Sports Sci. 2021 Mar;39(5):591-597. doi: 10.1080/02640414.2020.1837428. Epub 
      2020 Nov 1.