PMID- 33139637
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201226
IS  - 2227-9032 (Print)
IS  - 2227-9032 (Electronic)
IS  - 2227-9032 (Linking)
VI  - 8
IP  - 4
DP  - 2020 Nov 1
TI  - Similar Quality of Life and Safety in Patients Receiving Inpatient or Outpatient 
      Chemotherapy: A Focus on Esophageal Squamous Cell Carcinoma.
LID - 10.3390/healthcare8040447 [doi]
LID - 447
AB  - Quality of life (QoL) is a particularly important issue for cancer patients. This 
      study was designed to investigate the differences in QoL in esophageal squamous 
      cell carcinoma (ESCC) patients who underwent inpatient chemotherapy (IPCT) or 
      outpatient chemotherapy (OPCT). A total of 107 ESCC patients were enrolled, 
      including 53 patients in the IPCT group and 54 patients in the OPCT group. The 
      widely used and well-validated instruments European Organization for Research and 
      Treatment of Cancer Quality of Life Questionnaire Core 30 Items (EORTC QLQ-C30) 
      and Oesophageal Cancer Module (EORTC QLQ-OES18) were used to examine the QoL of 
      the two groups. In addition, the differences in adverse events (AEs) were 
      evaluated. The results of QLQ C-30 analysis showed that mean global quality of 
      life scores were similar between IPCT and OPCT groups, as were functional and 
      symptom scales. There were no significant differences in the functional and 
      symptom scales in the analysis of QLQ OES18 either. Most AEs of chemotherapy were 
      grades 1-2, and the majority of patients tolerated the side effects; no 
      statistically significant difference in AEs between these two groups was 
      mentioned. Our study suggests that the health-related QoL and adverse events in 
      ESCC patients who received IPCT or OPCT are similar. OPCT is reasonable and safe 
      in clinical practice.
FAU - Chen, Yen-Hao
AU  - Chen YH
AUID- ORCID: 0000-0002-5622-5490
AD  - Department of Hematology-Oncology, Kaohsiung Chang Gung Memorial Hospital and 
      Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.
AD  - School of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
AD  - Department of Nursing, Meiho University, Pingtung 912, Taiwan.
FAU - Chen, Su-Wei
AU  - Chen SW
AD  - Department of Nursing, Chang Jung Christian University, Tainan 711, Taiwan.
AD  - Department of Anesthesia, Tainan Municipal An-Nan Hospital, Tainan 709, Taiwan.
FAU - Lu, Hung-I
AU  - Lu HI
AD  - Department of Thoracic & Cardiovascular Surgery, Kaohsiung Chang Gung Memorial 
      Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.
FAU - Lo, Chien-Ming
AU  - Lo CM
AD  - Department of Thoracic & Cardiovascular Surgery, Kaohsiung Chang Gung Memorial 
      Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.
FAU - Li, Shau-Hsuan
AU  - Li SH
AD  - Department of Hematology-Oncology, Kaohsiung Chang Gung Memorial Hospital and 
      Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.
LA  - eng
GR  - MOST 107-2314-B-182A-156-MY3/National Science Council/
GR  - CMRPG8E0592/Kaohsiung Chang Gung Memorial Hospital/
GR  - CMRPG8J1061/Kaohsiung Chang Gung Memorial Hospital/
PT  - Journal Article
DEP - 20201101
PL  - Switzerland
TA  - Healthcare (Basel)
JT  - Healthcare (Basel, Switzerland)
JID - 101666525
PMC - PMC7711819
OTO - NOTNLM
OT  - esophageal cancer
OT  - inpatient chemotherapy
OT  - outpatient chemotherapy
OT  - quality of life
COIS- The authors declare no conflict of interest.
EDAT- 2020/11/04 06:00
MHDA- 2020/11/04 06:01
PMCR- 2020/11/01
CRDT- 2020/11/03 05:40
PHST- 2020/09/29 00:00 [received]
PHST- 2020/10/26 00:00 [revised]
PHST- 2020/10/30 00:00 [accepted]
PHST- 2020/11/03 05:40 [entrez]
PHST- 2020/11/04 06:00 [pubmed]
PHST- 2020/11/04 06:01 [medline]
PHST- 2020/11/01 00:00 [pmc-release]
AID - healthcare8040447 [pii]
AID - healthcare-08-00447 [pii]
AID - 10.3390/healthcare8040447 [doi]
PST - epublish
SO  - Healthcare (Basel). 2020 Nov 1;8(4):447. doi: 10.3390/healthcare8040447.