PMID- 3314359
OWN - NLM
STAT- MEDLINE
DCOM- 19871215
LR  - 20191022
IS  - 0065-1591 (Print)
IS  - 0065-1591 (Linking)
VI  - 335
DP  - 1987
TI  - Antidepressant drugs in anxiety disorders.
PG  - 57-74
AB  - The efficacy of tricyclic antidepressants and monoamine oxidase inhibitors (MAOI) 
      in the treatment of panic syndromes (panic disorder and agoraphobia with panic 
      attacks) and obsessive-compulsive disorders is reviewed. Imipramine has been 
      reported as significantly more effective against panic attacks than placebo or 
      other psychoactive drugs in 12 of 16 studies. Clomipramine has been found 
      superior to placebo or other psychoactive drugs in 5 controlled studies. The 
      effectiveness of these drugs is also reflected in a large number of open trials. 
      The MAOI phenelzine has been reported to be effective in 5 controlled studies. 
      Clomipramine is the best documented drug in the treatment of obsessive-compulsive 
      disorders. Its effectiveness has been documented in 7 controlled studies. Most 
      investigators consider the effects in panic syndromes as well as in 
      obsessive-compulsive disorders to be unrelated to the antidepressant effect.
FAU - Modigh, K
AU  - Modigh K
AD  - Department II, S:t Jorgen Hospital, Goteborg, Sweden.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Denmark
TA  - Acta Psychiatr Scand Suppl
JT  - Acta psychiatrica Scandinavica. Supplementum
JID - 0370365
RN  - 0 (Antidepressive Agents)
RN  - 0 (Monoamine Oxidase Inhibitors)
RN  - NUV44L116D (Clomipramine)
RN  - OGG85SX4E4 (Imipramine)
SB  - IM
MH  - Antidepressive Agents/*therapeutic use
MH  - Anxiety Disorders/*drug therapy
MH  - Clomipramine/therapeutic use
MH  - Humans
MH  - Imipramine/therapeutic use
MH  - Monoamine Oxidase Inhibitors/therapeutic use
MH  - Obsessive-Compulsive Disorder/drug therapy
MH  - Panic/drug effects
RF  - 77
EDAT- 1987/01/01 00:00
MHDA- 1987/01/01 00:01
CRDT- 1987/01/01 00:00
PHST- 1987/01/01 00:00 [pubmed]
PHST- 1987/01/01 00:01 [medline]
PHST- 1987/01/01 00:00 [entrez]
AID - 10.1111/j.1600-0447.1987.tb07749.x [doi]
PST - ppublish
SO  - Acta Psychiatr Scand Suppl. 1987;335:57-74. doi: 
      10.1111/j.1600-0447.1987.tb07749.x.