PMID- 33144164
OWN - NLM
STAT- MEDLINE
DCOM- 20210208
LR  - 20210208
IS  - 1879-1913 (Electronic)
IS  - 0002-9149 (Linking)
VI  - 140
DP  - 2021 Feb 1
TI  - Effect of Diabetes Mellitus and Left Ventricular Perfusion on Frequency of 
      Development of Heart Failure and/or All-cause Mortality Late After Acute 
      Myocardial Infarction.
PG  - 25-32
LID - S0002-9149(20)31184-X [pii]
LID - 10.1016/j.amjcard.2020.10.051 [doi]
AB  - Type 2 diabetes mellitus (DM) has a detrimental impact on cardiovascular 
      outcomes, with implications for prognosis following ST elevation myocardial 
      infarction (STEMI).The aim was to evaluate the impact of DM and myocardial 
      perfusion on the long-term risk of heart failure (HF) and/or all-cause mortality 
      following primary percutaneous coronary intervention (pPCI) for STEMI. A total of 
      406 STEMI patients (104 with DM) treated with pPCI were enrolled in this 
      observational study. Myocardial perfusion was reassessed with the Quantitative 
      Myocardial Blush Evaluator. Follow-up data on HF (ICD10 [International 
      Statistical Classification of Diseases] codes I50.0 - I50.9) and all-cause 
      mortality were obtained from the National Health Fund. During a 6-year follow-up, 
      36 (35%) patients with DM died compared with 45 (15%) patients without DM (p 
      <0.001). Also, 24 (23%) patients with DM developed HF compared with 51 (17%) 
      patients without DM (p = 0.20). Patients with DM and HF had the highest mortality 
      rate (75%), and those with DM and a QuBE score below the median value (9.0 arb. 
      units) had significantly higher risk of HF (hazard ratio [HR] =1.96, 95% CI 1.18 
      to 3.27, p = 0.0099) and the composite of HF and/or all-cause mortality 
      (HR = 1.89, 95% CI 1.33 to 2.69, p = 0.0004). In conclusion DM (type 2) and 
      diminished myocardial perfusion increase the risk of HF and/or all-cause 
      mortality during a 6-year follow-up after pPCI for STEMI.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Tomasik, Andrzej
AU  - Tomasik A
AD  - 2nd Department of Cardiology in Zabrze, Faculty of Medical Sciences in Zabrze, 
      Medical University of Silesia, Katowice, Poland.
FAU - Nabrdalik, Katarzyna
AU  - Nabrdalik K
AD  - Department of Internal Medicine, Diabetology and Nephrology, Faculty of Medical 
      Sciences in Zabrze, Medical University of Silesia, Katowice, Poland. Electronic 
      address: knabrdalik@sum.edu.pl.
FAU - Kwiendacz, Hanna
AU  - Kwiendacz H
AD  - Department of Internal Medicine, Diabetology and Nephrology, Faculty of Medical 
      Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
FAU - Radzik, Edyta
AU  - Radzik E
AD  - 2nd Department of Cardiology in Zabrze, Faculty of Medical Sciences in Zabrze, 
      Medical University of Silesia, Katowice, Poland.
FAU - Pigon, Katarzyna
AU  - Pigon K
AD  - 2nd Department of Cardiology in Zabrze, Faculty of Medical Sciences in Zabrze, 
      Medical University of Silesia, Katowice, Poland.
FAU - Mlynczak, Tomasz
AU  - Mlynczak T
AD  - 2nd Department of Cardiology in Zabrze, Faculty of Medical Sciences in Zabrze, 
      Medical University of Silesia, Katowice, Poland.
FAU - Sawczyn, Tomasz
AU  - Sawczyn T
AD  - Department of Physiology in Zabrze, Faculty of Medical Sciences in Zabrze, 
      Medical University of Silesia, Katowice, Poland.
FAU - Gumprecht, Janusz
AU  - Gumprecht J
AD  - Department of Internal Medicine, Diabetology and Nephrology, Faculty of Medical 
      Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
FAU - Nowalany-Kozielska, Ewa
AU  - Nowalany-Kozielska E
AD  - 2nd Department of Cardiology in Zabrze, Faculty of Medical Sciences in Zabrze, 
      Medical University of Silesia, Katowice, Poland.
FAU - Lip, Gregory Y H
AU  - Lip GYH
AD  - Liverpool Centre for Cardiovascular Science, University of Liverpool and 
      Liverpool Chest Hospital, Liverpool, United Kingdom.
LA  - eng
PT  - Journal Article
DEP - 20201102
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
SB  - IM
MH  - Aged
MH  - Cause of Death/trends
MH  - Diabetes Mellitus, Type 2/*complications/mortality
MH  - Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Ventricles/diagnostic imaging/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Poland/epidemiology
MH  - Prognosis
MH  - Retrospective Studies
MH  - Risk Assessment/*methods
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/etiology/*mortality/physiopathology
MH  - Survival Rate/trends
MH  - Time Factors
MH  - Ventricular Function, Left/*physiology
COIS- Declaration of Interests The authors declare that they have no known competing 
      financial interests or personal relations that could have appeared to influence 
      the work reported in this study.
EDAT- 2020/11/05 06:00
MHDA- 2021/02/09 06:00
CRDT- 2020/11/04 05:35
PHST- 2020/08/23 00:00 [received]
PHST- 2020/10/24 00:00 [revised]
PHST- 2020/10/27 00:00 [accepted]
PHST- 2020/11/05 06:00 [pubmed]
PHST- 2021/02/09 06:00 [medline]
PHST- 2020/11/04 05:35 [entrez]
AID - S0002-9149(20)31184-X [pii]
AID - 10.1016/j.amjcard.2020.10.051 [doi]
PST - ppublish
SO  - Am J Cardiol. 2021 Feb 1;140:25-32. doi: 10.1016/j.amjcard.2020.10.051. Epub 2020 
      Nov 2.