PMID- 33154317 OWN - NLM STAT- MEDLINE DCOM- 20210720 LR - 20210720 IS - 0974-5130 (Electronic) IS - 0377-4929 (Linking) VI - 63 IP - 4 DP - 2020 Oct-Dec TI - Anaplastic Lymphoma Kinase positive large B cell lymphoma of ileocaecal mesentery: A case report. PG - 615-617 LID - 10.4103/IJPM.IJPM_296_19 [doi] AB - ALK+ large B cell lymphoma (LBCL) is a very rare aggressive neoplasm. It accounts for less than 1% of diffuse large B cell lymphoma (DLBCL). This is a case report of ALK+ DLBCL in a 34-year-old woman with an ileocaecal mesenteric mass. Microscopically, the neoplastic cells were of high grade along with a spindle cell component. Immunohistochemistry revealed ALK+, MUM-1+, LCA+, Vimentin+, EMA+ and negative for CK 20, CK 7, neuroendocrine, melanocytic, muscle specific, and GIST panel markers. This case report, hence, presents the rarity of this tumor. FAU - Subramaniam, Aravinth AU - Subramaniam A AD - Department of Pathology, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu, India. FAU - Gnanasekaran, Divya AU - Gnanasekaran D AD - Department of Pathology, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu, India. FAU - Suruliraj, Saravanakumar AU - Suruliraj S AD - Department of Pathology, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu, India. FAU - Chinnusamy, Palanivelu AU - Chinnusamy P AD - Department of Pathology, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu, India. LA - eng PT - Case Reports PT - Journal Article PL - India TA - Indian J Pathol Microbiol JT - Indian journal of pathology & microbiology JID - 7605904 RN - 0 (Antineoplastic Agents) RN - 0 (Biomarkers, Tumor) RN - EC 2.7.10.1 (Anaplastic Lymphoma Kinase) SB - IM MH - Adult MH - Anaplastic Lymphoma Kinase/*genetics MH - Antineoplastic Agents/therapeutic use MH - Biomarkers, Tumor/genetics MH - Fatal Outcome MH - Female MH - Humans MH - Immunohistochemistry MH - In Situ Hybridization, Fluorescence MH - Lymphoma, Large B-Cell, Diffuse/*diagnosis/drug therapy/*genetics MH - Mesentery/pathology OTO - NOTNLM OT - Anaplastic lymphoma kinase positive large B cell lymphoma OT - CLTC-ALK gene OT - DLBCL OT - mesentery EDAT- 2020/11/07 06:00 MHDA- 2021/07/21 06:00 CRDT- 2020/11/06 05:52 PHST- 2020/11/06 05:52 [entrez] PHST- 2020/11/07 06:00 [pubmed] PHST- 2021/07/21 06:00 [medline] AID - IndianJPatholMicrobiol_2020_63_4_615_299304 [pii] AID - 10.4103/IJPM.IJPM_296_19 [doi] PST - ppublish SO - Indian J Pathol Microbiol. 2020 Oct-Dec;63(4):615-617. doi: 10.4103/IJPM.IJPM_296_19.