PMID- 33163867 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220418 IS - 2529-198X (Electronic) IS - 2529-198X (Linking) VI - 31 IP - 3 DP - 2020 Sep TI - MicroRNA155 Expression in Different Phenotypes and Genotypes of Behcet's Disease in a Sample of Egyptian Patients. PG - 337-340 LID - 10.31138/mjr.31.3.337 [doi] AB - AIM: To display microRNA155 (miRNA155) expression in different entities of Behcet's disease (BD), and to find out if expression is affected in more than one of disease status than another, either phenotypically, according to HLA B51 expression, presence of family history, or patients' age. METHODS: Thirty BD patients (13 of which were HLAB51 positive) and 15 healthy subjects' samples were obtained. White blood cell miRNA155 expression in both types of samples was estimated. RESULTS: Results showed that there is a degree of relation between decrease of miRNA155 expression and different disease aspects, and also, that miRNA155 has an inverse relation with the patients' ages. CONCLUSION: MiRNA155 might be used as a measure of disease of different phenotypes, and that any manifestation of the disease can happen when the expression level decreases. CI - (c) 2020 The Mediterranean Journal of Rheumatology (MJR). FAU - Hassouna, Sally S AU - Hassouna SS AD - Internal Medicine Department, Rheumatology and Immunology Unit, Faculty of Medicine, Alexandria University, Alexandria, Egypt. FAU - Tayel, Manal Y AU - Tayel MY AD - Internal Medicine Department, Rheumatology and Immunology Unit, Faculty of Medicine, Alexandria University, Alexandria, Egypt. FAU - Alzawawy, Ashraf I AU - Alzawawy AI AD - Clinical and Chemical Pathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt. FAU - Elkaffash, Dalal M AU - Elkaffash DM AD - Opthalmology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt. FAU - Abdel Hadi, Ahmed M AU - Abdel Hadi AM AD - Internal Medicine Department, Rheumatology and Immunology Unit, Faculty of Medicine, Alexandria University, Alexandria, Egypt. FAU - Elsayed, Eman H AU - Elsayed EH AD - Opthalmology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt. FAU - Amin, Rowayda M AU - Amin RM AD - Clinical and Chemical Pathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt. FAU - Tayae, Eman AU - Tayae E AD - Clinical and Chemical Pathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt. FAU - Elkayal, Alya AU - Elkayal A AD - Clinical and Chemical Pathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt. FAU - Nasr, Asmaa AU - Nasr A AD - Clinical and Chemical Pathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt. LA - eng PT - Journal Article DEP - 20200930 PL - Greece TA - Mediterr J Rheumatol JT - Mediterranean journal of rheumatology JID - 101730166 PMC - PMC7641019 OTO - NOTNLM OT - Behcet's OT - microRNA155 OT - phenotypes EDAT- 2020/11/10 06:00 MHDA- 2020/11/10 06:01 PMCR- 2020/09/30 CRDT- 2020/11/09 05:35 PHST- 2020/02/24 00:00 [received] PHST- 2020/06/03 00:00 [revised] PHST- 2020/06/21 00:00 [accepted] PHST- 2020/11/09 05:35 [entrez] PHST- 2020/11/10 06:00 [pubmed] PHST- 2020/11/10 06:01 [medline] PHST- 2020/09/30 00:00 [pmc-release] AID - MJR-31-3-337 [pii] AID - 10.31138/mjr.31.3.337 [doi] PST - epublish SO - Mediterr J Rheumatol. 2020 Sep 30;31(3):337-340. doi: 10.31138/mjr.31.3.337. eCollection 2020 Sep.