PMID- 33169346 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210319 IS - 1869-6953 (Print) IS - 1869-6961 (Electronic) IS - 1869-6961 (Linking) VI - 12 IP - 1 DP - 2021 Jan TI - African Cuisine-Centered Insulin Therapy: Expert Opinion on the Management of Hyperglycaemia in Adult Patients with Type 2 Diabetes Mellitus. PG - 37-54 LID - 10.1007/s13300-020-00958-z [doi] AB - The prevalence of diabetes in sub-Saharan Africa (SSA) is growing rapidly, and a steadily increasing number of adults are estimated to be living with type 2 diabetes mellitus (T2DM). Insulin therapy is the treatment of choice in patients who present with severe hyperglycaemia and in most of those who do not achieve target goals on oral hypoglycaemic agents. Initiating treatment with the appropriate type of insulin based on the meal patterns and lifestyle of the individual patient is a strategy that is more likely than others to improve glycaemic control and adherence. African cuisine typically has a high carbohydrate load. Given these predominantly carbohydrate-rich food habits, it is essential to modify this dietary pattern whilst at the same time ensuring that insulin therapy is initiated, titrated and maintained in a timely manner, as needed to suit the patient's habits. To date, there are no published clinical guidelines to guide practitioners and patients on tailoring insulin to match the high carbohydrate content in African cuisine. To address this gap, we have reviewed current insulin therapy practices and propose a patient-centric guide to insulin therapy based on African cuisine. A literature search was conducted for studies published in English up to November 2019 that focused on the choice of insulin and its dosing in relation to African foods. All articles extracted were reviewed by an expert group. The recommendation of the expert group was that basal-bolus and premix insulin regimens are best suited to manage post-meal glycaemia in African cuisine. The timing and constituents of the meal, portion sizes, glycaemic load and glycaemic index of meals should be considered when choosing the type of insulin and insulin regimen. Assessment of individual preferences and comorbidities should be prioritised and form an integral part of diabetes management. FAU - Mbanya, Jean Claude AU - Mbanya JC AUID- ORCID: 0000-0001-9651-8653 AD - Laboratory of Molecular Medicine and Metabolism, Biotechnology Center, University of Yaounde, Yaounde, Cameroon. jcmbanya@yahoo.co.uk. AD - Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde, Yaounde, Cameroon. jcmbanya@yahoo.co.uk. FAU - Lamptey, Roberta AU - Lamptey R AUID- ORCID: 0000-0002-4260-9442 AD - Department of Family Medicine, Korle Bu Teaching Hospital-University of Ghana, Accra, Ghana. AD - Department of Community Health, University of Ghana Medical School, Accra, Ghana. FAU - Uloko, Andrew E AU - Uloko AE AUID- ORCID: 0000-0002-3747-0300 AD - Department of Medicine, Bayero University Kano / Aminu Kano Teaching Hospital, Kano, Nigeria. FAU - Ankotche, Amos AU - Ankotche A AD - Department of Internal Medicine, Enocrinology and Geriatrics, Unit of Training and Research, Medical Science of Abidjan, University of Cote D'Ivoire, Abidjan, Ivory Coast. FAU - Moleele, Gontle AU - Moleele G AD - Department of Endocrinology, Bokamoso Private Hospital, Mmopane, Botswana. FAU - Mohamed, Gaman Ali AU - Mohamed GA AD - Comprehensive Diabetes Centre, Nairobi, Kenya. FAU - Ramracheya, Iswaraj AU - Ramracheya I AD - Heart and Wellness Centre, Wellkin Hospital, Moka, Mauritius. FAU - Ramaiya, Kaushik AU - Ramaiya K AD - Shree Hindu Mandal Hospital, Chusi Street, Dar es Salaam, Tanzania. FAU - Ndiweni, Malusi AU - Ndiweni M AD - Diabetes and Endocrine Centre, Harare, Zimbabwe. FAU - Mbaye, Maimouna Ndour AU - Mbaye MN AD - Centre du Diabete Marc Sankale, Dakar, Senegal. FAU - Bahendeka, Silver AU - Bahendeka S AD - Department of Internal Medicine, Mother Kevin Postgraduate Medical School, Uganda Martyrs University, Kampala, Uganda. FAU - Kalra, Sanjay AU - Kalra S AD - Department of Endocrinology, Bharti Hospital, Karnal, India. LA - eng PT - Journal Article PT - Review DEP - 20201109 PL - United States TA - Diabetes Ther JT - Diabetes therapy : research, treatment and education of diabetes and related disorders JID - 101539025 PMC - PMC7843662 OTO - NOTNLM OT - African cuisine OT - Carbohydrate OT - Insulin therapy OT - Meal pattern OT - Type 2 diabetes EDAT- 2020/11/11 06:00 MHDA- 2020/11/11 06:01 PMCR- 2020/11/09 CRDT- 2020/11/10 05:47 PHST- 2020/08/27 00:00 [received] PHST- 2020/10/23 00:00 [accepted] PHST- 2020/11/11 06:00 [pubmed] PHST- 2020/11/11 06:01 [medline] PHST- 2020/11/10 05:47 [entrez] PHST- 2020/11/09 00:00 [pmc-release] AID - 10.1007/s13300-020-00958-z [pii] AID - 958 [pii] AID - 10.1007/s13300-020-00958-z [doi] PST - ppublish SO - Diabetes Ther. 2021 Jan;12(1):37-54. doi: 10.1007/s13300-020-00958-z. Epub 2020 Nov 9.